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Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Antibiotic-resistant bacteria have been emerging at an alarming rate. In some of the scariest of these pathogens, the mechanism responsible for the bacteria's ability to defeat antibiotics is a complex protein molecule embedded in the bacterial cell wall -- the enzyme β-lactamase.

20 Jul 2013

Researchers visualize live cell-to-cell communication pathways in bacteria

Most bacteria are able to communicate with each other by secreting signaling molecules. Once the concentration of signals has reached a critical density (-the Quorum), the bacteria are able to coordinate their behavior

20 Jul 2013

Investigators report complete catalog of genes expressed in retina

Investigators at Massachusetts Eye and Ear and Harvard Medical School have published the most thorough description of gene expression in the human retina reported to date. In a study published today in the journal BMC Genomics, Drs. Michael Farkas, Eric Pierce and colleagues in the Ocular Genomics Institute at Mass. Eye and Ear reported a complete catalog of the genes expressed in the retina.

20 Jul 2013

NKX2-8 mutation in dogs may be a risk factor for human neural tube defects, say researchers

A gene related to neural tube defects in dogs has for the first time been identified by researchers at the University of California, Davis, and University of Iowa.

20 Jul 2013

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

Researchers at the University of Minnesota have identified infection-fighting and inflammation-suppressing functions for a gene associated with human autoimmune disease.

20 Jul 2013

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect some people from contracting the deadly disease.

20 Jul 2013

State highlights: D.C. health care providers continue wait for payments; Ga. plans Medicaid managed care for kids; Hospital chain seeks insurer license in Calif.

A selection of health policy stories from Virginia, the District of Columbia, California, Wisconsin, Georgia, South Carolina, Pennsylvania and Washington.

19 Jul 2013

New research uncovers biological ties between obesity and asthma

Genes linked to chronic inflammation in asthma may be more active in people who are obese, according to new research that uncovers several biological ties between obesity and asthma.

19 Jul 2013

Researchers receive $10M March of Dimes grant to study causes of premature birth

Researchers from Dartmouth's Institute for Quantitative Biomedical Sciences (iQBS), the Center for Integrative Biomedical Sciences, and the Center for Genomic Medicine at the Geisel School of Medicine are studying the unknown causes of premature birth, as part of a $10 million March of Dimes grant awarded to a research collaborative of seven U.S. universities and medical centers.

19 Jul 2013

Researchers identify cellular channels critical for hearing

Ending a 30-year search by scientists, researchers at Boston Children's Hospital have identified two proteins in the inner ear that are critical for hearing, which, when damaged by genetic mutations, cause a form of delayed, progressive hearing loss. Findings were published online July 18 by the journal Neuron.

19 Jul 2013

New data identifies specific cellular pathways by which RNS60 impacts Alzheimer's Disease

On Wednesday Revalesio Corporation presented new data at the Alzheimer's Association International Conference that identifies the specific cellular pathways by which Revalesio's lead investigational product, RNS60, impacts Alzheimer's Disease. This research, conducted in partnership with Rush University Medical Center, investigates a new category of therapeutics using Revalesio's novel nanotechnology platform.

19 Jul 2013

Scientists discover molecular switch that determines death or survival of cell

The study is the result of a collaboration of scientists at Karolinska Institutet in Sweden, University of Michigan, and University of California San Diego, USA, who were interested in finding out whether autophagy can be affected by events in the cell nucleus. Surprisingly, they discovered that a signal chain in the nucleus serves as a kind of molecular switch that determines whether the cell dies or survives.

19 Jul 2013

Kansas researchers defeat persistent bacteria known for causing infections in hospitals

Kansas State University researchers are defeating persistent bacteria known for causing infections in hospitals.

19 Jul 2013

Researchers identify genetic cause of severe obesity

Researchers at Boston Children's Hospital have identified a genetic cause of severe obesity that, though rare, raises new questions about weight gain and energy use in the general obese population. The research, published in the journal Science on July 19, involved genetic surveys of several groups of obese humans and experiments in mice.

19 Jul 2013

First Edition: July 18, 2013

Today's headlines include reports about the House vote to delay the health law's mandates as well as advance coverage of President Barack Obama's Thursday speech in which he touts the overhaul's benefits.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Researchers discover new protein that encourages ‘bad’ blood vessel growth

The discovery of a protein that encourages blood vessel growth, and especially 'bad' blood vessels - the kind that characterise diseases as diverse as cancer, age-related macular degeneration and rheumatoid arthritis - has been reported in the journal Nature.

18 Jul 2013

Researchers seek virus genes that allow animal hepatitis E strains infect humans

X.J. Meng, a University Distinguished Professor at Virginia Tech and a virologist at the Virginia-Maryland Regional College of Veterinary Medicine, has received a four-year, nearly $1.6 million grant from the National Institutes of Health to better understand the genetic elements that allow hepatitis E virus to transfer from animals to people.

17 Jul 2013

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

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17 Jul 2013

Genes News and Research

Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Researchers visualize live cell-to-cell communication pathways in bacteria

Investigators report complete catalog of genes expressed in retina

NKX2-8 mutation in dogs may be a risk factor for human neural tube defects, say researchers

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

State highlights: D.C. health care providers continue wait for payments; Ga. plans Medicaid managed care for kids; Hospital chain seeks insurer license in Calif.

New research uncovers biological ties between obesity and asthma

Researchers receive $10M March of Dimes grant to study causes of premature birth

Researchers identify cellular channels critical for hearing

New data identifies specific cellular pathways by which RNS60 impacts Alzheimer's Disease

Scientists discover molecular switch that determines death or survival of cell

Kansas researchers defeat persistent bacteria known for causing infections in hospitals

Researchers identify genetic cause of severe obesity

First Edition: July 18, 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Researchers discover new protein that encourages ‘bad’ blood vessel growth

Researchers seek virus genes that allow animal hepatitis E strains infect humans

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

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