Genetic News and Research

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Research findings bring scientists one step closer to preventing HIV infections

In a long-awaited finding, a team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells. The researchers also showed where maraviroc, an HIV drug, attaches to cells and blocks HIV’s entry.

13 Sep 2013

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

A new study has shown that, contrary to popular belief, local domestic animals are unlikely to be the major source of antibiotic resistant Salmonella in humans. The result comes from a detailed study of DNA from more than 370 Salmonella samples collected over a 22-year period.

13 Sep 2013

Genetic deficiency in autism linked to specific molecular and cellular consequences

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches that allow them to connect to brain circuits. The researchers also show in their study (online Sep. 12, 2013, in Neuron) that they could restore proper neuronal growth by compensating for the errant molecular mechanisms they identified.

13 Sep 2013

Researchers develop new ways of preventing septic shock

The body's immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights — that click on when there's an intruder rustling in the bushes, bacteria that seem suspect.

13 Sep 2013

Researchers show network of genes which enforce cooperative state within cells

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight with each other for domination.

13 Sep 2013

Study: 4% of head-trauma scans in children have unexpected results that may need follow up

The largest study of computed tomographic scans taken in emergency departments across the country for children with head injuries describes the prevalence of "incidental findings" - results that were not expected from the injury - and categorizes them by urgency.

13 Sep 2013

Pre-birth and early life nutrition affects children's cognitive, emotional and behavioural development

The statement "you are what you eat" is significant for the development of optimum mental performance in children as evidence is accumulating to show that nutrition pre-birth and in early life "programmes" long term health, well being, brain development and mental performance and that certain nutrients are important to this process.

13 Sep 2013

Data can help scientists, physicians match precision drugs to cancer's genetic traits

More than 5,000 genetic profiles of tumor DNA have been completed in a large research study by scientists at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital designed to speed the development of personalized cancer care with precision treatments.

13 Sep 2013

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Four new pre-clinical drug development projects at the National Institutes of Health will target a form of blindness and diseases characterized by cardiac problems. The projects were selected for their potential to treat specific rare diseases and to help scientists uncover new information that can be shared with other researchers.

13 Sep 2013

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Try as they might, House Republican leaders are having trouble stopping their colleagues from shooting themselves in the foot -- again. Having failed to approve any of the 12 annual appropriations bills that fund federal agencies, Congress has to pass a stopgap spending bill by Sept. 30 to keep much of the federal government from shutting down.

13 Sep 2013

Findings may help explain why some diabetic women prone to develop kidney failure

A genetic variant on chromosome 2 is strongly linked with kidney failure in diabetic women but not in men, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

13 Sep 2013

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 (NF1) and an associated condition called Costello syndrome.

12 Sep 2013

Harvard Stem Cell Institute, Evotec Team Up To Take On ALS

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12 Sep 2013

Columbia Labs Buys Molecular Profiles For $25M

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12 Sep 2013

Love Hormone May Play Role In Autism

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12 Sep 2013

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Since the sequence map of the human genome, the cost of sequencing the genome of an individual has fallen rapidly. This has resulted in a tremendous increase in the amount of human genomic data available to the international research community for the advancement of biomedical research. Yet, there is an absence of international mechanisms to support researchers in ensuring ethical and legal interoperability. In addition, the multiplicity and diversity of laws, standards and policies on sharing and accessing genetic and medical data represent major hurdles to international collaboration.

12 Sep 2013

New study to reduce unwanted side-effects of radiotherapy

Scientists from The University of Manchester are leading a new European study to come up with methods to reduce the unwanted side-effects of radiotherapy and improve cancer treatment.

From The University of Manchester 12 Sep 2013

Researcher characterises influenza A viruses in gulls and ducks

Ducks and gulls are the natural hosts of influenza A virus. Ragnhild Tønnessen's PhD research project has characterised influenza A viruses in gulls and ducks in Norway. Her discoveries may lead to a better understanding of the epidemiology and host adaptation of influenza A virus.

12 Sep 2013

NIH budget slashing may stall future pain research funding

Multi-faceted pain research discoveries within the last decade are bringing new hope for the estimated 100 million Americans with chronic pain. Unfortunately, translation of these scientific advances into clinical practice could be stalled without sufficient funding for both basic science and clinical pain research, according to the American Pain Society.

12 Sep 2013

Research holds promise for developing treatments for retinitis pigmentos

One of the leading causes of inherited blindness in humans, retinitis pigmentosa, is analogous to retinal dystrophies that lead to blindness in dogs. Because of their similarities, identifying gene mutations underlying several types of canine retinal dystrophies has suggested courses for research on RP in humans. These advances are significant for both humans and dogs.

12 Sep 2013

Genetic News and Research

Research findings bring scientists one step closer to preventing HIV infections

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

Genetic deficiency in autism linked to specific molecular and cellular consequences

Researchers develop new ways of preventing septic shock

Researchers show network of genes which enforce cooperative state within cells

Study: 4% of head-trauma scans in children have unexpected results that may need follow up

Pre-birth and early life nutrition affects children's cognitive, emotional and behavioural development

Data can help scientists, physicians match precision drugs to cancer's genetic traits

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Findings may help explain why some diabetic women prone to develop kidney failure

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

Harvard Stem Cell Institute, Evotec Team Up To Take On ALS

Columbia Labs Buys Molecular Profiles For $25M

Love Hormone May Play Role In Autism

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

New study to reduce unwanted side-effects of radiotherapy

Researcher characterises influenza A viruses in gulls and ducks

NIH budget slashing may stall future pain research funding

Research holds promise for developing treatments for retinitis pigmentos

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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