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NCI awards $1.5M grant to LSUHSC researcher to study role of chronic inflammation in cancer

Yan Cui, PhD, Associate Professor of Microbiology, Immunology, & Parasitology at LSU Health Sciences Center New Orleans and the LSUHSC Stanley S. Scott Cancer Center, has been awarded a $1.5 million grant over five years by the National Cancer Institute to study the role of chronic inflammation in the development and progression of cancer.

19 Jul 2013

Researchers identify cellular channels critical for hearing

Ending a 30-year search by scientists, researchers at Boston Children's Hospital have identified two proteins in the inner ear that are critical for hearing, which, when damaged by genetic mutations, cause a form of delayed, progressive hearing loss. Findings were published online July 18 by the journal Neuron.

19 Jul 2013

Researchers identify genetic cause of severe obesity

Researchers at Boston Children's Hospital have identified a genetic cause of severe obesity that, though rare, raises new questions about weight gain and energy use in the general obese population. The research, published in the journal Science on July 19, involved genetic surveys of several groups of obese humans and experiments in mice.

19 Jul 2013

FDA grants orphan drug designation to ARMAGEN's AGT-182 for treatment of Hunter syndrome

ARMAGEN announced today that the U.S. Food and Drug Administration has granted orphan drug designation to its lead product AGT-182 for the treatment of mucopolysaccharidosis type II (also known as Hunter syndrome or MPS II).

19 Jul 2013

First Edition: July 18, 2013

Today's headlines include reports about the House vote to delay the health law's mandates as well as advance coverage of President Barack Obama's Thursday speech in which he touts the overhaul's benefits.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Breast cancer pilot study: Patients benefit from treatments guided by molecular profiling

The Side-Out Foundation's breast cancer pilot study, led by the Translational Genomics Research Institute, Translational Drug Development and Scottsdale Healthcare, has shown that cancer patients do better when their treatment is guided by molecular profiling.

18 Jul 2013

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

The National Institutes of Health has awarded Virginia Commonwealth University a grant totaling $1.8 million to study the biology of allergic disease - work which may one day point researchers to the development of therapies to fight asthma, allergy and inflammatory conditions such as rheumatoid arthritis, multiple sclerosis and heart disease.

18 Jul 2013

Researchers discover new protein that encourages ‘bad’ blood vessel growth

The discovery of a protein that encourages blood vessel growth, and especially 'bad' blood vessels - the kind that characterise diseases as diverse as cancer, age-related macular degeneration and rheumatoid arthritis - has been reported in the journal Nature.

18 Jul 2013

Study shows CMEs can predict risk of cancer in type 2 diabetes patients

Certain chromosomal abnormalities of the preleukemic type appear to be over-represented in patients with type 2 diabetes (T2D) who are suffering from vascular complications. This finding may provide a partial explanation for the higher rates of cancer-related mortality observed among patients with this type of diabetes.

18 Jul 2013

Researchers seek virus genes that allow animal hepatitis E strains infect humans

X.J. Meng, a University Distinguished Professor at Virginia Tech and a virologist at the Virginia-Maryland Regional College of Veterinary Medicine, has received a four-year, nearly $1.6 million grant from the National Institutes of Health to better understand the genetic elements that allow hepatitis E virus to transfer from animals to people.

17 Jul 2013

Three scientists receive Young Investigator Award from Bert L. & N. Kuggie Vallee Foundation

The Bert L. and N. Kuggie Vallee Foundation announces, today, the first recipients of its Young Investigator Award.

17 Jul 2013

TAp73 protein frequently overexpressed in wide range of human tumors

They say you can pick your friends, but not your family. The same may hold true for related proteins. The protein TAp73 is a relative of the well-known, tumor-suppressor protein p53. It shares extensive common gene sequences with p53 and, as suggested by some previous studies, it may function similar to p53 to prevent tumor formation.

17 Jul 2013

Progress made in understanding Pulmonary Arterial Hypertension

The next step has been made into isolating the origin of cells linked to the progressive disorder Pulmonary Arterial Hypertension.

17 Jul 2013

People at risk for Alzheimer's disease take steps to prevent dementia

People who found out they carried an uncommon genetic risk for Alzheimer's disease did not experience more anxiety, depression or distress than non-carriers, and were more active in efforts to reduce their risk of Alzheimer's disease - by exercising, eating a healthy diet and taking recommended vitamins and medications - report researchers from the Perelman School of Medicine at the University of Pennsylvania today at the 2013 Alzheimer's Association International Conference (AAIC).

17 Jul 2013

Smokers who seem healthy have damaged airway cells similar to cells found in aggressive lung cancer

Smokers who've received a clean bill of health from their doctor may believe cigarettes haven't harmed their lungs. However, researchers at Weill Cornell Medical College have found that even smokers who seem healthy have damaged airway cells, with characteristics similar to cells found in aggressive lung cancer.

17 Jul 2013

Dartmouth's professor selected as Kavli Fellow of NAS 2013 for significant contributions to science

Professor Jason H. Moore of Dartmouth's Geisel School of Medicine has been selected as a Kavli Fellow of the National Academy of Sciences (NAS) for 2013. The Kavli program honors young scientists who are considered leaders in their fields and have made significant contributions to science.

17 Jul 2013

Diet low in fish, seafood can cause nutrition gap of omega-3 fatty acids in children and adults

Because of a diet low in fish and seafood, children and adults in North America and other parts of the world, have a "nutrition gap" of omega-3 fatty acids, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA),according to a presentation at the 2013 Institute of Food Technologists (IFT) Annual Meeting & Expo in Chicago-.

17 Jul 2013

Blood vessels grown from pluripotent stem cells able to function inside mice

Researchers at Johns Hopkins have coaxed stem cells into forming networks of new blood vessels in the laboratory, then successfully transplanted them into mice. The stem cells are made by reprogramming ordinary cells, so the new technique could potentially be used to make blood vessels genetically matched to individual patients and unlikely to be rejected by their immune systems, the investigators say.

17 Jul 2013

Genetic News and Research

NCI awards $1.5M grant to LSUHSC researcher to study role of chronic inflammation in cancer

Researchers identify cellular channels critical for hearing

Researchers identify genetic cause of severe obesity

FDA grants orphan drug designation to ARMAGEN's AGT-182 for treatment of Hunter syndrome

First Edition: July 18, 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Breast cancer pilot study: Patients benefit from treatments guided by molecular profiling

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

Researchers discover new protein that encourages ‘bad’ blood vessel growth

Study shows CMEs can predict risk of cancer in type 2 diabetes patients

Researchers seek virus genes that allow animal hepatitis E strains infect humans

Three scientists receive Young Investigator Award from Bert L. & N. Kuggie Vallee Foundation

TAp73 protein frequently overexpressed in wide range of human tumors

Progress made in understanding Pulmonary Arterial Hypertension

People at risk for Alzheimer's disease take steps to prevent dementia

Smokers who seem healthy have damaged airway cells similar to cells found in aggressive lung cancer

Dartmouth's professor selected as Kavli Fellow of NAS 2013 for significant contributions to science

Diet low in fish, seafood can cause nutrition gap of omega-3 fatty acids in children and adults

Blood vessels grown from pluripotent stem cells able to function inside mice

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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