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Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.

23 Sep 2022

Study finds strong links between certain gut bacteria and small molecules in the blood

There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites.

23 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus -; the tube connecting the throat to the stomach.

22 Sep 2022

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Is SARS-CoV-2 hiding in your fat cells? A study by Stanford Medicine investigators shows that SARS-CoV-2 can infect human fat tissue.

22 Sep 2022

Researchers receive $3.4 million NIH grant to assess soccer's tradeoffs with respect to brain health

More than 25 million Americans play soccer, the world's most popular sport. Soccer significantly benefits brain health by boosting aerobic capacity and oxygen and blood flow to the brain, but it also has a downside: Recent studies show that highly repetitive heading of the ball is associated with structural brain changes and worse cognitive performance similar to brain damage caused by concussion.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1.

21 Sep 2022

UEA researchers make important discovery about how prostate cancer may begin

Researchers at the University of East Anglia have made an important discovery about how prostate cancer may start to develop.

21 Sep 2022

Global burden of type 1 diabetes likely to double by 2040, study predicts

An estimated 8.4 million people were living with Type 1 Diabetes (T1D) across the globe in 2021, according to the results of a new modeling study published in The Lancet Diabetes & Endocrinology.

21 Sep 2022

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

An aggressive type of pediatric brain tumor, medulloblastoma, exists in a pre-malignant form at birth after initially developing during the first or second trimester of pregnancy, according to a new international study.

21 Sep 2022

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Researchers evaluated the association between guild-level microbiome signature and the severity and prognosis of SARS-CoV-2 infections by a genome-level metagenomic analysis.

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Genetic News and Research

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Study finds strong links between certain gut bacteria and small molecules in the blood

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Researchers receive $3.4 million NIH grant to assess soccer's tradeoffs with respect to brain health

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

UEA researchers make important discovery about how prostate cancer may begin

Global burden of type 1 diabetes likely to double by 2040, study predicts

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Common genetic variants of APOE associated with COVID mortality

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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