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B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

​An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. [More]
Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and metastasize. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage. [More]
Proteins that regulate energy metabolism are essential for stem cell formation

Proteins that regulate energy metabolism are essential for stem cell formation

Proteins that regulate energy metabolism are essential for stem cell formation, University of Washington researchers find. [More]
Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

In a new study that could help doctors extend the lives of patients awaiting liver transplants, a Rice University-led team of researchers examined the metabolic breakdown that takes place in liver cells during late-stage cirrhosis and found clues that suggest new treatments to delay liver failure. [More]

UH scientists working to develop next generation of prostate cancer therapies

A University of Houston scientist and his team are working to develop the next generation of prostate cancer therapies, which are targeted at metabolism. [More]

Novel SCLC tumour suppressor gene discovered

Inactivation of the MYC-associated factor X gene, MAX, may play a significant role in the development of small-cell lung cancer, scientists believe. [More]
Researchers present new drug candidate that selectively kills cancer cells through starvation

Researchers present new drug candidate that selectively kills cancer cells through starvation

In a study published in Nature Communications, researchers at Karolinska Institutet and Uppsala University in Sweden present a new drug candidate, which selectively kills dormant cells within a cancer tumour through starvation. [More]

Scientists reveal important degradation pathway of sulpho-glucose

By discovering sulpho-glycolysis, researchers of the University of Konstanz reveal an important degradation pathway. [More]

Scientists believe that new links between brain cells help encode new memories and skills

In adults, some brain regions retain a "childlike" ability to establish new connections, potentially contributing to our ability to learn new skills and form new memories as we age, according to new research from Washington University School of Medicine in St. Louis and the Allen Institute for Brain Science in Seattle. [More]
Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Although brain growth slows as individuals age, some regions of the brain continue to develop for longer than others, creating new connections and remodeling existing circuitry. [More]
Researchers discover new way to make chemotherapy treatment effective for pancreatic cancer patients

Researchers discover new way to make chemotherapy treatment effective for pancreatic cancer patients

Scientists from The University of Manchester - part of Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients. [More]
Aerobic glycolysis is a cause of malignancy, show Berkeley Lab researchers

Aerobic glycolysis is a cause of malignancy, show Berkeley Lab researchers

Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, Mina Bissell, Distinguished Scientist with Berkeley Lab's Life Sciences Division and a leading authority on breast cancer, has shown that aerobic glycolysis - glucose metabolism in the presence of oxygen - is not the consequence of the cancerous activity of malignant cells but is itself a cancerous event. [More]
New approach for combating seasonal flu

New approach for combating seasonal flu

Reducing glucose metabolism dials down influenza viral infection in laboratory cell cultures, providing an entirely new approach for combating seasonal flu, according to research that will be presented on Sunday, Dec. 15, at the American Society for Cell Biology annual meeting in New Orleans. [More]
Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

​A protector for PTEN, a tumor-thwarting protein often missing in cancer cells, has emerged from research led by scientists at The University of Texas MD Anderson Cancer Center published online at Nature Cell Biology this week. [More]

Copper intake via food and water can accelerate growth of tumors

Copper imbalances have been associated with a number of pathological conditions, including cancer. Publishing in PNAS scientists at EPFL have found that copper in drinking water - given at the maximum levels permitted in public water supplies - accelerated the growth of tumors in mice. On the other hand, reducing copper levels reduced tumor growth. [More]
Novel approach confirms dysfunctional energy production in schizophrenia

Novel approach confirms dysfunctional energy production in schizophrenia

A method of directly assessing creatine kinase in the brain provides “direct and compelling” evidence for abnormal bioenergetics in the brains of patients with schizophrenia, say the study authors. [More]
Video demonstrates high throughput screening of cellular bioenergetics of multiple cell lines

Video demonstrates high throughput screening of cellular bioenergetics of multiple cell lines

INTEGRA has published a video demonstrating how its VIAFLO 96 handheld electronic pipette, used in conjunction with the Seahorse Bioscience XF96 Extracellular Flux Analyzer, provides high throughput screening of the cellular bioenergetics of multiple cell lines. [More]

Novel metabolic imaging method enhances prostate cancer diagnosis

Metabolic imaging with hyperpolarized pyruvate is a noninvasive and well-tolerated method for visualizing prostate tumors, US scientists have shown. [More]
Research opens potential new avenue for cancer treatment

Research opens potential new avenue for cancer treatment

Scientists at The University of Texas MD Anderson who identified a protein's dual role in cancer promotion have discovered a way to shut it down, opening a potential new avenue for cancer treatment. [More]

New type of chemical modification affects proteins, could provide insights into causes of cancer

Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose. [More]