Glycoprotein News and Research

RSS

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

Breast milk microbiome changes after COVID-19 vaccination, linked to enhanced infant protection

Study explored the association between BNT162b2 vaccine-induced antibodies and the breast milk microbiome in 49 breastfeeding mothers, revealing that post-vaccination alterations in the microbiome were linked to humoral protection against SARS-CoV-2.

9 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Researchers use cryo-EM and molecular dynamics to reveal conformational changes in the spike proteins of human coronavirus HKU1 upon binding with a receptor. Findings unveil the complexity of beta coronavirus attachment, suggesting a more intricate mechanism of host cell invasion than previously understood.

8 Oct 2023

Green, matcha, and black tea: Effective weapons against Omicron subvariants, research reveals

The efficacy of tea and its catechins in deactivating the Omicron subvariant.

5 Oct 2023

New insights into how smoking influences certain metabolites to increase type 2 diabetes risk

New research being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct) finds that cigarette smoking increases the risk of developing type 2 diabetes in part by affecting a variety of metabolites-;small chemicals produced in the processes of metabolism-;that circulate in the bloodstream.

3 Oct 2023

New discovery could delay relapse in triple-negative breast cancer

A team of researchers at the Medical University of Vienna has discovered that dormant tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein called P-glycoprotein (P-gp).

3 Oct 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

The power of nanobodies: How they impact COVID-19 immune response

The structures of 340 antibodies (Abs) and 83 nanobodies.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Researchers discover that antiviral lectins like BOA can effectively inhibit SARS-CoV-2 and its variants by targeting spike glycans, opening doors for potential pan-coronavirus treatments. The study reveals that BOA's multivalent interactions make it a potent inhibitor against a range of viral variants, offering promise for future therapeutic strategies.

14 Sep 2023

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

New genetic factors that affect the plasma apolipoprotein E levels.

8 Sep 2023

Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Researchers identify a new SARS-CoV-2 variant, BA.2.86, with enhanced ability to evade immunity but lower infectivity compared to current variants. The study highlights the need for global monitoring due to its potential to become a predominant strain if it gains infectivity through mutations.

6 Sep 2023

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Glycoprotein News and Research

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Breast milk microbiome changes after COVID-19 vaccination, linked to enhanced infant protection

Research explains the reason behind delay in therapeutic action of antidepressants

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Green, matcha, and black tea: Effective weapons against Omicron subvariants, research reveals

New insights into how smoking influences certain metabolites to increase type 2 diabetes risk

New discovery could delay relapse in triple-negative breast cancer

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

The power of nanobodies: How they impact COVID-19 immune response

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News