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Also in global health news: HIV/AIDS in Bangladesh; river blindness in Tanzania; potential immune system booster; compounds might fight TB

BDNews24.com reports on a new $13 million U.S.-government initiative aimed at "providing HIV-prevention services to two million at-risk people in Bangladesh including injecting drug users, male, female and transgender sex workers and their clients, and HIV-positive people through a network of 50 health centres." USAID will partner with Family Health International (FHI) to implement the program (9/17).

18 Sep 2009

President Obama's commitment to global AIDS and health is in doubt: GAA

Later today, Ambassador Eric Goosby will be sworn in as the U.S. Global AIDS Coordinator. "While we welcome Ambassador Goosby to his new post, and look forward to working with him on a broad range of issues that affect the health and well-being of the world's vulnerable populations, there are a number of as-yet unanswered questions about the true commitment of the Obama Administration to global AIDS and health, including PEPFAR [President's Emergency Plan for AIDS Relief]," said Dr. Paul Zeitz, GAA executive director.

18 Sep 2009

Discovery of key molecule may yield new therapies for AIDS and cancer

Discovery by Hebrew University of Jerusalem researchers of an additional role for a key molecule in our bodies provides a further step in world-wide efforts to develop genetic regulation aimed at controlling many diseases, including AIDS and various types of cancers.

17 Sep 2009

Biomagnetics and U.S. Government laboratory continue contract negotiations

Biomagnetics Diagnostics Corp., (PINK SHEETS:BMGP) a developer of revolutionary diagnostic systems and technology for HIV, hepatitis, tuberculosis, and malaria detection, today announced the Company is in continuing contract negotiations to acquire the rights to Integrated Optical Biosensor System (IBOS) technology developed by one of the U.S. Government’s top national security research institutions.

17 Sep 2009

Funding, health professional shortage could prevent South Africa from reaching 2011 ARV target, Health Minister says

South Africa's shortage of health professionals combined with a budget shortfall of over $130 million for the government's HIV programs could keep the country from reaching its goal of providing 80 percent of the people living with HIV/AIDS in need of treatment with antiretroviral drugs (ARVs) by 2011.

17 Sep 2009

Leading doctors call for climate change action to prevent 'global health catastrophe'

On Wednesday, the British Medical Journal (BMJ) and the Lancet simultaneously published an editorial (available here and here) and an accompanying letter (here and here) from 18 doctor association leaders to highlight the need for action at a December U.N. conference on climate change in Copenhagen, Reuters reports (Doyle, 9/16).

17 Sep 2009

Study: Antiretroviral drugs may prevent HIV infection in women

Hopeful that some of the same antiretroviral (ARV) drugs used to treat HIV infection can also prevent it, researchers from the Microbicide Trials Network have enrolled the first participants into a new, large-scale clinical trial testing two approaches of the strategy in women.

17 Sep 2009

Researchers discover HIV Nef protein's role in cell mobility inhibition

In order to be able to ward off disease pathogens, immune cells must be mobile and be able to establish contact with each other. The working group around Professor Dr. Oliver Fackler in the Virology Department of the Hygiene Institute of the Heidelberg University Hospital has discovered a mechanism in an animal model revealing how HIV, the AIDS pathogen, cripples immune cells: Cell mobility is inhibited by the HIV Nef protein.

17 Sep 2009

VOICE clinical study for testing the efficacy of two HIV prevention strategies

A new, large-scale clinical trial is examining whether antiretroviral medications normally used to treat HIV infection can also prevent HIV infection in women when applied as a vaginal gel or taken as oral tablets once daily.

16 Sep 2009

Matrix Laboratories receives tentative FDA approval for its NDA

Mylan Inc. today announced that its privately held Indian subsidiary, Matrix Laboratories Limited, has received tentative approval from the U.S. Food and Drug Administration (FDA) under the President's Emergency Plan for AIDS Relief (PEPFAR) for its New Drug Application (NDA) for Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate Tablets, 600 mg/300 mg/300 mg.

16 Sep 2009

Inovio’s novel platform for developing DNA based vaccines to be discussed at EmTech

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that Dr. J. Joseph Kim, CEO, has been invited to present at EmTech, the Emerging Technologies Conference hosted by MIT and produced by MIT’s Technology Review magazine. The conference will take place September 22nd - 24th on the MIT campus in Cambridge, MA.

16 Sep 2009

Precise T cell correlates of protection need to be identified for vaccine design

T cells are key players in the immune response to HIV, which are able to delete infected cells. This capacity is used for vaccine development against HIV. "To date however, success of this strategy remains elusive. Our understanding of T cell efficacy is still limited, and we need to identify precise T cell correlates of protection that could guide rationale vaccine design", says Victor Appay, Group leader HIV Pathogenesis and Immunosenescence, Hopital Pitie-Salpetriere, Paris, at the 2nd European Congress of Immunology ECI 2009 in Berlin.

16 Sep 2009

Pros and cons of HIV treatments in developing countries

Palumbo is co-leading a clinical study of anti-HIV medicines in Africa and India for the International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT). The randomized trial found that a cohort of 82 HIV-infected children ages 6 to 35 months responded better to treatment with the protease-inhibiting drug lopinavir (LPV/r) than did a cohort of 82 children in the same age group who received the anti-retroviral drug nevirapine (NVP).

16 Sep 2009

Urgent vaccine requirements for treating epidemic diseases voiced at ECI 2009

As a result of dominant media coverage of new epidemic threats such as swine influenza, other infection risks receive less public attention than they deserve. "We would like to bring to everybody's attention that the infectious diseases with the most severe consequences continue to be old acquaintances such as tuberculosis, HIV/AIDS, malaria and hepatitis C. About six million people worldwide die of these diseases every year," says Professor Dr. Dr. h. c. Stefan H. E. Kaufmann, Director of the Max Planck Institute for Infection Biology in Berlin, at the 2nd European Congress of Immunology ECI 2009.

16 Sep 2009

Opinion piece calls for enhanced U.S.-Russia health collaboration

While legislators in Moscow attempt to reform the Russian health system in a way that is "strikingly similar" to the reform process in the U.S. and "[g]iven the importance of the U.S.-Russia relationship ... our two countries have a historic opportunity to expand our health collaboration and, in so doing, improve our diplomatic ties," former U.S. Senate Majority Leader Bill Frist.

16 Sep 2009

Andersonville Arts Weekend art sales proceeds to support HIV-affected families

During the Arts weekend, over 25 of Olmetti's works and installations will be featured at SIR Spa. Proceeds from art sales will benefit the Chicago House, in support pf the mission of Chicago House and Social Service Agency to provide housing and supportive services to HIV-affected families and individuals who may also be impacted by poverty, homelessness, substance abuse, and mental illness.

15 Sep 2009

Cytheris' INSPIRE study data of HIV-infected patients with low CD4 T cell counts announced

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced presentation of data from an interim analysis of CLI-107-06 (INSPIRE), a Phase I/IIa study of HIV-infected patients with low CD4 T cell counts. The patients were treated with a three-injection cycle of the Company’s investigative immune-modulator, recombinant human Interleukin-7 (CYT107).

15 Sep 2009

FluCide more effective than Tamiflu

NanoViricides, Inc. (OTC BB: NNVC.OB) (the "Company"), announced today that Anil Diwan, PhD, President of the Company presented a talk at NanoBusiness 2009 - the 8th annual NanoBusiness Conference in Chicago, IL, on Wednesday, September 9th.

15 Sep 2009

MSD's ISENTRESS approved by the EU Commission for treating HIV-1 infection in adult patients

Merck Sharp & Dohme Limited (MSD) announced today that ISENTRESS® (raltegravir) has been granted an expanded licence from the European Union Commission (Commission) for use in combination with other antiretroviral (ARV) medicinal products for the treatment of HIV-1 infection in adult patients, including adult patients starting HIV-1 therapy for the first time (treatment-naïve), as well as treatment-experienced adult patients.

15 Sep 2009

Anti-fungal pill found to be effective for treating oral candidiasis

A once-daily medication option for treating the most common mouth infection in HIV/AIDS patients has shown to be just as effective and safe as taking an anti-fungal pill five times a day, according to a Henry Ford Hospital study.

15 Sep 2009