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Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Olfactory health - how well we are able to smell - is a reliable marker of the health of the brain, but the "smell identification tests" commonly used in studies of olfactory health do not offer a complete picture of what is happening. [More]
Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis. [More]
Public health experts support new federal rule to protect nonsmoking public housing residents

Public health experts support new federal rule to protect nonsmoking public housing residents

In response to a new federal rule mandating smoke-free policies in federally funded public housing authorities, three public health experts applaud the efforts of the U.S. Department of Housing and Urban Development to protect nonsmoking residents from the harmful effects of tobacco exposure. [More]
MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment. [More]
Scientists find altered blood-brain barrier and increased intestinal permeability in people with ASD

Scientists find altered blood-brain barrier and increased intestinal permeability in people with ASD

Autism spectrum disorder (ASD) has the dubious distinction of being the fastest-growing developmental disability in the U.S., according to the Centers for Disease Control and Prevention. [More]
MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy. [More]
Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection. [More]
MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems. [More]
Mylan announces U.S. launch of generic Concerta Tablets

Mylan announces U.S. launch of generic Concerta Tablets

Mylan N.V., today announced the U.S. launch of Methylphenidate Hydrochloride Extended-Release Tablets USP, 18 mg, 27 mg, 36 mg and 54 mg, a generic version of Janssen's Concerta Tablets. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Blocking protein that initiates immune response against viral infections may help combat HIV

Blocking protein that initiates immune response against viral infections may help combat HIV

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV. [More]
First large-scale clinical study of long-acting injectable HIV drug begins

First large-scale clinical study of long-acting injectable HIV drug begins

The first large-scale clinical trial of a long-acting injectable drug for HIV prevention began today. [More]
Study finds chances for recovery of women with anorexia or bulimia nervosa

Study finds chances for recovery of women with anorexia or bulimia nervosa

A study from Massachusetts General Hospital (MGH) investigators finds that, contrary to what is often believed, around two thirds of women with anorexia nervosa or bulimia nervosa will eventually recover from their eating disorders. [More]
Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

The bionic pancreas system developed by Boston University investigators proved better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, over 11 days. [More]
Combination therapy holds great promise to clear precancerous skin lesions

Combination therapy holds great promise to clear precancerous skin lesions

A combination of two FDA-approved drugs - a topical chemotherapy and an immune-system-activating compound - was able to rapidly clear actinic keratosis lesions from patients participating in a clinical trial. [More]
Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects. [More]
New review shows how automated telephone systems could play vital role in delivery of health care

New review shows how automated telephone systems could play vital role in delivery of health care

A new Cochrane Review, summarizing data from 132 trials of automated telephone systems in preventing and managing long-term health conditions, concludes that they probably have the potential to play an important role in the delivery of health care. [More]
Families are probably not financially burdened by their childrens' Down Syndrome medical care

Families are probably not financially burdened by their childrens' Down Syndrome medical care

The first study to analyze the out-of-pocket costs to families for the medical care of children and adolescents with Down syndrome finds that monthly costs - averaged over the first 18 years of life - are less than $100 a month more than the costs for care of a typically developing child. The report published in American Journal of Medical Genetics, Part A also finds that the additional costs are lower when the child is older. [More]
NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

National Institutes of Healthscientists have established in mice a way to study potentially life-threatening meningitis caused by Salmonella. [More]
MGH researchers develop magnetic coils for selective and reliable neural stimulation

MGH researchers develop magnetic coils for selective and reliable neural stimulation

Massachusetts General Hospital researchers have developed what appears to be a significant improvement in the technology behind brain implants used to activate neural circuits responsible for vision, hearing or movement. [More]
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