Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the first half year of 2011.

25 Aug 2011

USPTO issues Notice of Allowance for Cortex AMPAKINE molecules to treat respiratory depression

Cortex Pharmaceuticals, Inc. announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a patent that protects the use of AMPAKINE molecules for the treatment or prevention of respiratory depression.

25 Aug 2011

Heart failure risk rises in people with diastolic dysfunction: Study

New research suggests that a common form of heart trouble called diastolic dysfunction appears to worsen over time and may lead to an increased risk of heart failure. In people with diastolic dysfunction, which often comes with advancing age, the heart's left ventricle fills with blood in an abnormal way and is accompanied by elevated filling pressures.

24 Aug 2011

Trophos awarded US patent covering use of novel cardioprotective compound

Trophos SA a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, announced today that the United States Patent and Trademark Office (USPTO) has granted a patent for the use of their novel mitochondrial pore modulator, TRO40303, for cytoprotection. The patent provides coverage for the use of Trophos’ TRO40303 to reduce the cardiac reperfusion injury that contributes significantly to the morbidity and mortality seen after a heart attack (myocardial infarction - MI).

23 Aug 2011

Research reveals significant increase in infections associated with cardiac electrophysiological devices

New research from the Jefferson Heart Institute shows that patients in the United States who receive cardiac electrophysiological devices (CIEDs), including permanent pacemakers and implantable cardioverter-defibrillators (ICDs) are now at greater risk of contracting an infection over the life span of the device.

23 Aug 2011

Stem cells of oral mucosa stay young, says Tel Aviv University researcher

While highly potent embryonic stem cells are often the subject of ethical and safety controversy, adult-derived stem cells have other problems. As we age, our stem cells are less pliant and less able to transform into the stem cells that science needs to find breakthrough treatments for disease.

23 Aug 2011

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

Obesity, diabetes, and cardiovascular diseases are daunting modern-day epidemics. In Western Europe more than 50% of the population is overweight and approximately 15 million people die from cardiovascular diseases such as heart attacks and stroke every year. These conditions are often caused by disorders of fat metabolism, resulting in a massive accumulation of fat in various tissues and of cholesterol in the walls of arteries.

22 Aug 2011

Cortex second quarter net loss decreases to $356,000

Cortex Pharmaceuticals, Inc. reported a net loss of approximately $356,000, or $0.00 per share, for the quarter ended June 30, 2011, compared with a net loss of approximately $2,454,000, or $0.04 per share, for the corresponding prior year period, with the difference reflecting revenues in the current year period from the Company's option agreement with Servier, France's largest privately held pharmaceutical company.

18 Aug 2011

National analysis identifies Columbus as one of the Hypertension Hot Spots in the U.S.

A national analysis conducted by Sperling's BestPlaces and sponsored by Takeda Pharmaceuticals North America, Inc., identified Columbus, Ohio, as one of the nation's Hypertension Hot Spots, or cities that have hypertension risk factors and complications.

18 Aug 2011

New tool can identify patients at high risk of venous thromboembolism

A new risk prediction tool can identify patients at high risk of serious blood clots (known as venous thromboembolism) who might need preventative treatment, says a study published on bmj.com today.

17 Aug 2011

UCSD Sulpizio Cardiovascular Center receives ACCF/AHA's GWTG Gold award

UC San Diego Health System is one of only 167 hospitals nationwide to receive the American College of Cardiology Foundation's (ACCF) NCDR ACTION Registry-GWTG (Get with the Guidelines) Gold Performance Achievement Award for 2011.

17 Aug 2011

Obesity directly causes electrical abnormalities of the heart

University of Adelaide research has shown for the first time that obesity directly causes electrical abnormalities of the heart.

17 Aug 2011

Scientists gain new insight on role of stem cells in embryonic heart development

Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important in some types of cancer.

16 Aug 2011

AHRQ's new Spanish-language guide on heart medications

A free, illustrated easy-to-read pamphlet that compares drugs for preventing heart attacks, heart failure or strokes in people with stable coronary heart disease is one of six new Spanish-language publications from HHS' Agency for Healthcare Research and Quality that help patients compare treatments for common illnesses.

16 Aug 2011

Toclizumab for juvenile rheumatoid arthritis

The arthritis drug Toclizumab could be a boon for hundreds of children suffering from severe arthritis. It has been re-launched in children after being already licensed for the treatment of adults. At least two thirds of children taking tocizilumab have been able to return to a normal life, after many were bedridden or forced into wheelchairs by the disease, the clinical studies reveal.

16 Aug 2011

Galectin second quarter net loss increases to $3.9 million

Galectin Therapeutics Inc., the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today reported its financial results for the second quarter and first six months, ended June 30, 2011.

12 Aug 2011

Medical College of Wisconsin to establish National Center for Systems Biology

The Medical College of Wisconsin has received a five-year, $13 million grant to establish a National Center for Systems Biology.

12 Aug 2011

PUFA intake linked to reduced risk of heart failure, kidney disease and preterm delivery

Omega-3 polyunsaturated fats (PUFAs) found in seafood may reduce arterial stiffness and improve heart function in chronic heart failure, according to new research. These fats, better known as EPA and DHA, may also help in the immediate aftermath of a stroke.

11 Aug 2011

FDA approves Abbott's RX Herculink Elite Renal Stent System for renal artery stenosis

Abbott today announced it has received U.S. Food and Drug Administration (FDA) approval for the RX Herculink Elite® Renal Stent System for the treatment of renal artery stenosis (narrowing of the main arteries supplying blood to the kidneys) in patients with uncontrolled hypertension (high blood pressure).

10 Aug 2011

Trastuzumab drug increases risk of heart problems in elderly breast cancer patients

The first study to investigate the effect of the breast cancer drug trastuzumab (Herceptin) on heart and vascular function in elderly patients has found that it increases the risk of heart problems, particularly in women with a history of heart disease, diabetes or both.

10 Aug 2011

Heart Failure News and Research

Further Reading

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

USPTO issues Notice of Allowance for Cortex AMPAKINE molecules to treat respiratory depression

Heart failure risk rises in people with diastolic dysfunction: Study

Trophos awarded US patent covering use of novel cardioprotective compound

Research reveals significant increase in infections associated with cardiac electrophysiological devices

Stem cells of oral mucosa stay young, says Tel Aviv University researcher

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

Cortex second quarter net loss decreases to $356,000

National analysis identifies Columbus as one of the Hypertension Hot Spots in the U.S.

New tool can identify patients at high risk of venous thromboembolism

UCSD Sulpizio Cardiovascular Center receives ACCF/AHA's GWTG Gold award

Obesity directly causes electrical abnormalities of the heart

Scientists gain new insight on role of stem cells in embryonic heart development

AHRQ's new Spanish-language guide on heart medications

Toclizumab for juvenile rheumatoid arthritis

Galectin second quarter net loss increases to $3.9 million

Medical College of Wisconsin to establish National Center for Systems Biology

PUFA intake linked to reduced risk of heart failure, kidney disease and preterm delivery

FDA approves Abbott's RX Herculink Elite Renal Stent System for renal artery stenosis

Trastuzumab drug increases risk of heart problems in elderly breast cancer patients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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