Hemochromatosis News and Research

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Hemochromatosis is the most common form of iron overload disease. Primary hemochromatosis, also called hereditary hemochromatosis, is an inherited disease. Secondary hemochromatosis is caused by anemia, alcoholism, and other disorders.

Human lymphocytes produce hepcidin that regulate iron levels in the body: Study

For some years now a small group of scientists have been pioneering a revolutionary idea - that the vertebrate immune system could have a role in the regulation of iron in the body. And now, a work soon to be published in the journal Immunology, shows that human lymphocytes (white blood cells) actually produce hepcidin, the most important protein in the regulation of iron levels in the body.

22 Apr 2010

EHSI incorporates outpatient treatment options into MedAnywhere HHC Module

Emerging Healthcare Solutions, Inc. revealed today that they are working to incorporate outpatient treatment options into the new MedAnywhere medical iPhone app and that the first module to be added to development will be for cost saving Hemochromatosis management.

20 Apr 2010

Pathway Genomics' personal Genetic Health Report now available

Pathway Genomics Inc., a U.S. based genetic testing company, announced the immediate availability of its personal Genetic Health Report. This customized and innovative personal genetic health report contains information on more than 70 health conditions, including pharmacogenetics (prescription medication response), propensity for complex disease, and carrier status (pre-pregnancy health).

17 Mar 2010

Researchers discover new target for drugs to prevent common iron deficiency

The discovery of a major player in the body's regulation of iron levels should provide a new target for drugs that prevent common iron deficiency as well as rare, potentially deadly iron overload, researchers said.

29 Jan 2010

Comparison study finds no significant differences in post-transplant survival rates of NASH and ETOH groups

Researchers at the University of Miami School of Medicine compared the outcomes of cirrhotic patients who underwent liver transplants for nonalcoholic steatohepatitis (NASH) versus alcoholic liver disease (ETOH) and found no statistically significant differences in post-transplant survival rates between the NASH and ETOH groups

25 Nov 2009

Research to develop small-molecule drug that blocks excess iron absorption

Excess iron in the body, if left unchecked, can form toxic deposits in major organs leading to serious conditions including heart failure, diabetes, liver cirrhosis, arthritis, and even infertility. Iron overload can be a consequence of a genetically mutated gene known as hereditary hemochromatosis, or a consequence of red blood cell transfusions, required as life saving treatments, for patients with diseases such as thalassemia.

25 Sep 2009

Researchers map iron transport protein - may help people suffering from blood iron disorders

Montana State University scientists in the Department of Chemistry and Bio-chemistry published new research this week that could one day affect the lives of millions around the world who suffer from blood iron disorders.

21 May 2008

Europe's most common genetic disease is a liver disorder

Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems.

7 Feb 2008

Untreated blood disorder leads to liver cancer and arthritis

Australian researchers have discovered that more than one quarter of men with hemochromatosis develop liver cancer, arthritis and other complications.

20 Jan 2008

Life savers in the gut

Researchers from the European Molecular Biology Laboratory (EMBL) have discovered that proteins that regulate the body's iron household play a vital role in making sure enough nutrients and water are absorbed in the intestine.

10 Jan 2008

H63D genetic defect linked to increased risk of stroke

One of the most common genetic defects passed on through families significantly increases a person's chance of having a stroke, according to a study published in the March 27, 2007, issue of Neurology?, the scientific journal of the American Academy of Neurology.

2 Apr 2007

Researchers discover how to fight iron disorders with a drug against hypertension

We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred.

12 Feb 2007

Faster method for detecting disease-causing mutations developed by Pitt researchers

University of Pittsburgh researcher Alexander Star and colleagues at a California-based company, Nanomix, Inc., have developed devices made of carbon nanotubes that can find mutations in genes causing hereditary diseases, they report in the Jan. 16 issue of the journal Proceedings of the National Academy of Science.

24 Jan 2006

Liver plays crucial role in iron metabolism

A new study in the December Cell Metabolism reveals an unexpected connection between a tumor suppressor gene in the liver and the normally careful control over the amount of iron absorbed from the diet.

7 Dec 2005

Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

St. Jude Children’s Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients.

1 Sep 2005