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MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment. [More]
AAV-based gene therapy to treat liver disorders advances into human testing

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Special Issue on digestive cancers offers five articles from experts in Latin America

Special Issue on digestive cancers offers five articles from experts in Latin America

ecancermedicalscience has published a new Special Issue on digestive cancers in Latin America, bringing together five articles from experts in the region. [More]
Scientists unravel novel role of signalling protein in common type of liver cancer

Scientists unravel novel role of signalling protein in common type of liver cancer

The most common type of liver cancer, called Hepatocellular carcinoma, is one of the most prevalent tumours worldwide. [More]
Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells. [More]
HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

A new study presented this week at The Liver Meeting — held by the American Association for the Study of Liver Diseases — found patients with hepatitis C who take direct-acting antiviral medication are at no higher risk for developing liver cancer than those who do not take the medication. [More]
Researchers identify proteins in the blood that could improve detection of pancreatic cancer

Researchers identify proteins in the blood that could improve detection of pancreatic cancer

Pancreatic cancer is one of the most lethal forms of cancer because early stage symptoms are relatively light, often resulting in it being discovered only after spreading to other organs. In order to improve the prognosis of pancreatic cancer, the development of methods for early detection of pancreatic cancer with a blood test is important. [More]
AMSBIO announces new edition of its popular organoid culture handbook

AMSBIO announces new edition of its popular organoid culture handbook

AMSBIO announces an extended and updated edition of its popular Organoid Culture Handbook. Launched at the EMBO Symposium on Organoids: Modelling Organ Development and Disease in 3D Culture, the new 24-page handbook includes valuable information about the latest available products, protocols, example results and research paper citations. [More]
Selenium status linked to cancer risk

Selenium status linked to cancer risk

As a nutritional trace element, selenium forms an essential part of our diet. In collaboration with the International Agency for Research on Cancer, researchers from Charité - Universitätsmedizin Berlin have been able to show that high blood selenium levels are associated with a decreased risk of developing liver cancer. [More]
Can-Fite BioPharma reports financial results, provides update on drug development programs

Can-Fite BioPharma reports financial results, provides update on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the six months ended June 30, 2016 and updates on its drug development programs. [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults. [More]
New method helps characterize immune cells in tumor tissues

New method helps characterize immune cells in tumor tissues

Despite recent achievements in the development of cancer immunotherapies, only a small group of patients typically respond to them. Predictive markers of disease course and response to immunotherapy are urgently needed. [More]
Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades. [More]
Low levels of blood selenium may increase risk of liver cancer

Low levels of blood selenium may increase risk of liver cancer

A new study, published in current issue of The American Journal of Clinical Nutrition, shows that the highest levels of blood selenium or of selenoprotein P, the protein that distributes selenium from the liver around the body, are associated with a decreased risk of developing liver cancer (particularly hepatocellular carcinoma), even when all other major liver cancer risk factors are taken into account. [More]
CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

Non-alcoholic steatohepatitis (NASH) is a serious hepatic condition that precedes hepatocellular carcinoma (HCC) and is currently untreatable. [More]
FIB-4 index predicts HBV-related HCC

FIB-4 index predicts HBV-related HCC

Japanese researchers reveal an association between elevated FIB-4 index 24 weeks after the initiation of nucleos(t)ide analogue therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. [More]
Infant HBV vaccination prevents HCC in children, young adults

Infant HBV vaccination prevents HCC in children, young adults

Immunisation against hepatitis B virus in infants protects against the development of hepatocellular carcinoma in not only children but also young adults, a Taiwanese study finds. [More]
Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Oral multikinase inhibitor regorafenib achieves significantly improved survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase III RESORCE trial, presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain. [More]
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