Hippocampus News and Research RSS Feed - Hippocampus News and Research

The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.
Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression in the weeks after giving birth, and an opportunity to intervene before symptoms become debilitating. [More]
Research shows new neural circuits arise when hippocampus is disabled

Research shows new neural circuits arise when hippocampus is disabled

When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways - often far from the damaged site. [More]
Findings could help develop new approaches to treat depression and memory loss in the elderly

Findings could help develop new approaches to treat depression and memory loss in the elderly

Scientists have known for some time that exercise induces neurogenesis in a specific brain region, the hippocampus. However, until this study, the underlying mechanism was not fully understood. [More]

Complex network of molecules controls formation and activity of neuronal connections

Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed extracellular matrix. [More]
New form of electroconvulsive therapy could prevent adverse cognitive side effects

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Electroconvulsive therapy (ECT) is the most effective acute treatment for severe major depression. However, even with newer forms of ECT, there remains a significant risk of adverse cognitive effects, particularly memory problems. [More]
Discovery raises hope for severe forms of human epilepsy

Discovery raises hope for severe forms of human epilepsy

Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UC San Francisco researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy. [More]
Virtual reality reveals new clues on how cells determine place

Virtual reality reveals new clues on how cells determine place

Leaving the house in the morning may seem simple, but with every move we make, our brains are working feverishly to create maps of the outside world that allow us to navigate and to remember where we are. [More]
Neuralstem gets approval from FDA for dosing cohort patients in NSI-189 Phase Ib in MDD treatment

Neuralstem gets approval from FDA for dosing cohort patients in NSI-189 Phase Ib in MDD treatment

Neuralstem, Inc. announced that it has received approval from the Food and Drug Administration (FDA) to begin dosing the third and final cohort of patients in its ongoing Phase Ib to test the safety of NSI-189 in the treatment of major depressive disorder (MDD). [More]

Schizophrenia patients misinterpret anger

A study shows that patients with schizophrenia struggle to recognize angry facial expressions, often mistaking them for fear. [More]
CI therapy appears to benefit children with cerebral palsy

CI therapy appears to benefit children with cerebral palsy

Researchers at the University of Alabama at Birmingham (UAB) report that children with cerebral palsy who underwent Constraint Induced Movement therapy (CI therapy) saw a significant increase in grey matter volume in areas of the brain associated with movement. [More]

Study: Stem cell transplant heals neurological deficits in mice

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember. [More]

Research reveals how three-dimensional, volumetric, space is perceived in mammalian brains

Animals navigate and orient themselves to survive - to find food and shelter or avoid predators, for example. Research conducted by Dr. Nachum Ulanovsky and research student Michael Yartsev of the Weizmann Institute's Neurobiology Department, published today in Science, reveals for the first time how three-dimensional, volumetric, space is perceived in mammalian brains. [More]

Excess glutamate drives schizophrenia in high-risk individuals

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center published in the current issue of Neuron. [More]

Tel Aviv University researcher reveals the missing link between brain patterns and Alzheimer's

Evidence indicates that the accumulation of amyloid-beta proteins, which form the plaques found in the brains of Alzheimer's patients, is critical for the development of Alzheimer's disease, which impacts 5.4 million Americans. [More]
New research reveals how acute stress primes brain for improved performance

New research reveals how acute stress primes brain for improved performance

Overworked and stressed out? Look on the bright side. Some stress is good for you. "You always think about stress as a really bad thing, but it's not," said Daniela Kaufer, associate professor of integrative biology at the University of California, Berkeley. [More]
People who practice sport have better cognitive performance, researchers say

People who practice sport have better cognitive performance, researchers say

New scientific evidence seems to confirm the famous Roman saying "Mens sana in corpore sano". Researchers from the University of Granada have demonstrated that people who normally practice sport have a better cognitive performance than those with bad physical health. [More]
Researchers employ new techniques to identify neuron communication in rat brain

Researchers employ new techniques to identify neuron communication in rat brain

There are cells in your brain that recognize very specific places, and have that as one of their main jobs. These cells, called place cells, are found in an area behind your temple called the hippocampus. While these cells must be sent information from nearby cells to do their job, so far no one has been able to determine exactly what kind of nerve cells, or neurons, work with place cells to craft the code they create for each location. [More]

Epileptic seizures can propagate via anatomically connected networks in brain

The seizures that affect people with temporal-lobe epilepsy usually start in a region of the brain called the hippocampus. [More]
New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

There are two regions in the brain that continue to produce new neurons well into adulthood. One of these regions is the hippocampus and as we converse this region is actively involved in memory formation, mood regulation and cognition. [More]
Scientists identify key molecule responsible for triggering chemical processes in brain

Scientists identify key molecule responsible for triggering chemical processes in brain

Scientists have identified a key molecule responsible for triggering the chemical processes in our brain linked to our formation of memories. The findings, published in the journal Frontiers in Neural Circuits, reveal a new target for therapeutic interventions to reverse the devastating effects of memory loss. [More]