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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.
Study links dopamine D2 receptor to long-term episodic memory

Study links dopamine D2 receptor to long-term episodic memory

A European study led by Umea University Professor Lars Nyberg, has shown that the dopamine D2 receptor is linked to the long-term episodic memory, which function often reduces with age and due to dementia. [More]
Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others. [More]
Positive environment can reverse trauma-related behavioral alterations in mice

Positive environment can reverse trauma-related behavioral alterations in mice

Traumatic experiences in childhood increase the risk of developing behavioral and psychiatric disorders later in life. It is also known that the consequences of a trauma can likewise be observed in the children of people affected even if those children have themselves not experienced any trauma. [More]
Study shows skill-related memory persists in amnesia patients

Study shows skill-related memory persists in amnesia patients

She no longer recognizes a Van Gogh, but can tell you how to prepare a watercolor palette. [More]
Study finds link between pontosubicular necrosis and placental pathology

Study finds link between pontosubicular necrosis and placental pathology

Pediatric and Developmental Pathology – A stillbirth occurs when a baby is born without any signs of life. Placental pathology is found to be related to the cause of death in a significant number of pregnancies that result in stillbirth [More]
Researchers aim to explore whether cell transplantation can treat temporal lobe epilepsy

Researchers aim to explore whether cell transplantation can treat temporal lobe epilepsy

Researchers at Cardiff University's School of Medicine are about to explore whether it's possible to treat human temporal lobe epilepsy (TLE) by transplanting immature neuron cells into the brain. [More]
Researchers find new method to replicate one of earliest changes in Alzheimer’s disease

Researchers find new method to replicate one of earliest changes in Alzheimer’s disease

Researchers at the Babraham Institute have found a way to replicate one of the earliest changes in Alzheimer's disease in a dish. This means that it should now be possible to find out a lot more about why it happens - and how to stop it. The new findings are published in the journal Molecular Neurodegeneration and supported by the charity Alzheimer's Research UK. [More]
New technique may help replace brain cells, restore memory

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function. [More]
NMNAT2 enzyme may help protect against debilitating effects of neurodegenerative disorders

NMNAT2 enzyme may help protect against debilitating effects of neurodegenerative disorders

A study led by biomedical researchers at Indiana University has found evidence that an enzyme known as NMNAT2 may help protect against the debilitating effects of certain degenerative brain diseases, including Alzheimer's. [More]
Researchers shed more light on how brain rhythms organize memories across time

Researchers shed more light on how brain rhythms organize memories across time

Just as members of an orchestra need a conductor to stay on tempo, neurons in the brain need well-timed waves of activity to organize memories across time. In the hippocampus--the brain's memory center--temporal ordering of the neural code is important for building a mental map of where you've been, where you are, and where you are going. [More]
Miniature microscope helps neuroscientists identify how the brain links different memories over time

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Using a miniature microscope that opens a window into the brain, UCLA neuroscientists have identified in mice how the brain links different memories over time. While aging weakens these connections, the team devised a way for the middle-aged brain to reconnect separate memories. [More]
Specific monocyte immune cells serve as link between gut bacteria and the brain

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports. [More]
Many biomarkers for PD fail to inform on progression

Many biomarkers for PD fail to inform on progression

Longitudinal monitoring of 30 tests for marker candidates in early Parkinson's disease has found that just 10 show significant changes commensurate with disease progression. [More]
Estrogen-inhibiting drug may suppress dangerous brain seizures

Estrogen-inhibiting drug may suppress dangerous brain seizures

A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study. [More]
Scientists find tau protein as better marker of Alzheimer's disease

Scientists find tau protein as better marker of Alzheimer's disease

A buildup of plaque and dysfunctional proteins in the brain are hallmarks of Alzheimer's disease. While much Alzheimer's research has focused on accumulation of the protein amyloid beta, researchers have begun to pay closer attention to another protein, tau, long associated with this disease but not studied as thoroughly, in part, because scientists only recently have developed effective ways to image tau. [More]
Mice study reveals signs of stress-related early maturation in vital brain region

Mice study reveals signs of stress-related early maturation in vital brain region

Intuition is all one needs to understand that stress in early childhood can create lifelong psychological troubles, but scientists have only begun to explain how those emerge in the brain. [More]
Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

Aging takes its toll on the brain, and the cells of the hippocampus--a brain region with circuitry crucial to learning and memory--are particularly vulnerable to changes that can lead to Alzheimer's disease or cognitive decline. With the hope of counteracting the changes that can lead to these two conditions, researchers at Rockefeller University and their colleagues have begun examining the effects of a drug known to affect this circuitry. [More]
Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism and schizophrenia. [More]
Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

The cannabinoid type 2 receptor - also called "CB2 receptor" - is a special membrane protein. Its function is to receive chemical signals that control cellular activity. "Until now, this receptor was considered part of the immune system without function in nerve cells. [More]
Researchers explore effects of adolescent obesity on cognitive performance in adulthood

Researchers explore effects of adolescent obesity on cognitive performance in adulthood

The Franco-Mexican research explores the cognitive performance in adulthood when the subjects have been exposed to an obesogenic environment during adolescence. [More]
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