Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

People living with HIV respond well to COVID-19 infection and vaccination

Researchers examine the antibody response to natural infection or COVID-19 vaccination in individuals living with HIV infection.

7 Aug 2023

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys.

3 Aug 2023

Genome-wide study finds link between CHD1L gene and HIV control

"We searched for human genetic variation that associates with spontaneous control of HIV and identified a novel region in the genome that is only variable in populations of African ancestries," says Professor Jacques Fellay at EPFL's School of Life Sciences.

2 Aug 2023

Child-friendly HIV drug could improve treatment outcomes

Researchers at the University of Colorado Anschutz Medical Campus have helped confirm the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).

2 Aug 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Study highlights advantages of syphilis self-testing: convenience, privacy, and rapid results

Researchers performed a meta-analysis on the utility of syphilis self-testing (SST).

26 Jul 2023

Donating a kidney can be safe for people living with HIV, study shows

Based on findings from a study published today in the journal The Lancet Regional Health - Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.

24 Jul 2023

Improving gut health may be key to slowing HIV progression to AIDS

Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.

24 Jul 2023

Salk researchers uncover molecular mechanisms of HIV drug resistance

Salk Institute researchers, in collaboration with the National Institutes of Health, have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV.

21 Jul 2023

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Researchers have identified a potential immune biomarker associated with pulmonary TB in active patients compared to controls.

19 Jul 2023

AI and infection control: preventing infectious disease outbreaks and pandemics

Researchers discussed the role of artificial intelligence (AI) in preventing outbreaks of infectious diseases and future pandemics.

19 Jul 2023

Immunodiagnosis: Unleashing the potential of personalized immunotherapy

Researchers discuss the concept of immunodiagnosis and explores the potential of artificial intelligence in ID systems for precise tumor immunotherapy.

18 Jul 2023

Gender, socioeconomic factors, and race/ethnicity linked to comorbidities among smokers with HIV

High rates of smoking among people with HIV are associated with high rates of comorbid health problems – which are associated with characteristics including gender, race/ethnicity, and socioeconomic status, according to a study in the July issue of The Journal of the Association of Nurses in AIDS Care.

14 Jul 2023

Novel approach: intranasal vaccination strategy targets Omicron COVID-19 variants

Researchers tested the efficacy of a two to three-dose intranasal (IN) regimen of the NDV-HXP-S vaccine.

14 Jul 2023

Scientists discover mechanism of cell death in people living with HIV

Professor Simona Stäger's team has made a breakthrough in the study of the human immunodeficiency virus (HIV).

13 Jul 2023

Towards Zika preparedness: immunogenicity insights from vaccine research

Study assesses the safety and immunogenicity of an inactivated Zika virus vaccine candidate.

30 Jun 2023

New digital assay can directly measure the presence of HIV in single drop of blood

A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies.

27 Jun 2023

Beyond expectations: study finds treatment success gap in drug-resistant Tuberculosis

Researchers performed a review of global treatment outcomes of drug-resistant Tuberculosis.

27 Jun 2023

Researchers take promising step forward in the battle against HIV

A multi-institutional research group led by researchers from Tokyo Medical and Dental University (TMDU) has made a significant and promising step forward in our ability to treat human immunodeficiency virus type 1 (HIV-1), the virus underlying acquired immunodeficiency syndrome (AIDS).

21 Jun 2023

Newborn screening for "bubble-baby" disease boosts survival of children

Screening newborns for severe combined immunodeficiency disease (SCID) significantly increases the survival of children after bone marrow transplantation, a new North American study finds.

21 Jun 2023