Immunoglobulin News and Research

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Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The current preliminary investigation study published in the journal Nutrients sought to investigate the longevity of anti-SARS-CoV-2 immunoglobulin (Ig)A and IgG in breast milk during the in vitro-simulated gastrointestinal digestion.

24 May 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

Study reveals the cross-protective role of Omicron infection in vaccinated individuals

A new study compares the cross-protective humoral responses to different SARS-CoV-2 variants induced by vaccination or infection.

23 May 2022

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Researchers evaluate the persistence of anti-SARS-CoV-2 IgA and IgG in breast milk before and after in vitro gastrointestinal digestion.

23 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Researchers assessed the impact of BNT162b2 coronavirus disease 2019 (COVID-19) vaccination on antibody acquisition.

23 May 2022

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Resarchers discuss the ability of shark-derived antibodies to protect against multiple variants of SARS-CoV-2.

23 May 2022

Women who are pregnant or nursing should receive a COVID booster vaccination

In a recent study posted to the medRxiv* preprint server, researchers evaluated the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccination in nursing and pregnant women.

23 May 2022

Anti-SARS-CoV-2 titers predict COVID severity

A recent study published in the journal Viruses reported that antibody titers against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could serve as a marker for the severity of coronavirus disease 2019 (COVID-19).

22 May 2022

Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

Serologic response to SARS-CoV-2 may predict COVID-19 severity

A new study reported that antibody titers against SARS-CoV-2 could serve as a marker for the severity of COVID-19.

20 May 2022

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Researchers performed a molecular analysis of cross-reactive antibodies targeted against the receptor-binding domain of SARS-CoV-2 strains among the general population.

20 May 2022

NIH team documents various types of neuropathy after COVID vaccination

In a recent study posted to the medRxiv* preprint server, researchers investigated if coronavirus disease 2019 (COVID-19) vaccination could result in neuropathic symptoms.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Researchers evaluated the humoral and T lymphocyte immune responses against SARS-CoV-2 variants of concern among mild COVID-19 convalescent patients in South Australia.

19 May 2022

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Researchers developed an enzyme-linked immunosorbent assay to detect antibodies against SARS-CoV-2 in urine samples.

19 May 2022

Immunoglobulin News and Research

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

Study reveals the cross-protective role of Omicron infection in vaccinated individuals

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Study shows a strong negative association between BNT162b2 vaccination-induced S1 IgG concentration and age

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Women who are pregnant or nursing should receive a COVID booster vaccination

Anti-SARS-CoV-2 titers predict COVID severity

Study outlines risk factors for autoimmune hepatitis after liver transplant

Serologic response to SARS-CoV-2 may predict COVID-19 severity

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

NIH team documents various types of neuropathy after COVID vaccination

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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