Immunoglobulin News and Research

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Children exposed to maltreatment present a response-to-stress pattern like that of adolescents

The acute psychosocial stress states stimulate the secretion of an antibody type protein which is decisive in the first immune defence against infection, but only after puberty. However, children with a history of maltreatment present a similar response to that of adolescents, which suggests there is an early maturation of the immune system in these cases.

11 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

Evasion of COVID-19 vaccine-medicated mucosal immunity by SARS-CoV-2 Omicron

Researchers depicted the evasion of the SARS-CoV-2 Omicron variant to mucosal immunity in SARS-CoV-2 vaccine recipients.

10 May 2022

Heightened antibody responses in COVID-19 booster vaccinated individuals following SARS-CoV-2 Omicron

Investigators illustrated that a SARS-CoV-2 Omicron infection post-booster vaccination imparts robust, long-lasting immunity against future re-infections.

10 May 2022

Elevated and sustained autoantibodies following COVID-19

A new study demonstrated that autoantibody levels rise following acute SARS-CoV-2 infection and remain to be elevated for about six months.

10 May 2022

Exploring low serum volume assays for SARS-CoV-2 antibodies

Researchers developed several non-commercial/in-house low serum volume assays for detecting and characterizing SARS-CoV-2 antibodies.

9 May 2022

Third BNT162b2 dose elicits more durable immune response than second dose

Researchers evaluated the durability of immune responses post-third dose of the BNT162b2 vaccine against SARS-CoV-2.

9 May 2022

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Researchers explored the underlying mechanism resulting in thymic atrophy and subsequent lymphopenia in COVID-19 patients.

9 May 2022

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

A recent article published in Science Translational Medicine demonstrated that mucosally delivered adenovirus type 5 (Ad5)-based COVID-19 vaccination minimized COVID-19 transmission and severity.

9 May 2022

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

In a recent study posted to the Research Square* preprint server, researchers tested the safety and immunogenicity of a third dose of coronavirus disease 2019 (COVID-19) prototype messenger ribonucleic acid (mRNA)-1273 versus a variant vaccine and a bivalent vaccine formulation.

5 May 2022

The war against COVID-19: reinfection, vaccines, and herd immunity

A communication published in the journal Epidemiologia aimed to answer several questions concerning neutralizing antibodies against SARS-CoV-2, herd immunity, and COVID-19 vaccines.

4 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

Pets living in households with COVID-19 are high likely to seroconvert and become ill

In a recent study published in the journal Emerging Infectious Diseases, researchers investigated whether pet dogs and cats in the households of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected humans were at risk of infection.

3 May 2022

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

A new study analyzed multivalent messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine constructs against certain β-coronaviruses (β-CoVs).

3 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Nearly 60% of Americans infected by Omicron

A recent study published in the Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report (MMWR) assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-induced viral antibodies (Abs) seroprevalence in the United States (US).

28 Apr 2022

Immunoglobulin News and Research

Children exposed to maltreatment present a response-to-stress pattern like that of adolescents

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

Evasion of COVID-19 vaccine-medicated mucosal immunity by SARS-CoV-2 Omicron

Heightened antibody responses in COVID-19 booster vaccinated individuals following SARS-CoV-2 Omicron

Elevated and sustained autoantibodies following COVID-19

Exploring low serum volume assays for SARS-CoV-2 antibodies

Third BNT162b2 dose elicits more durable immune response than second dose

Study investigates the cause of lymphopenia as seen in COVID-19 patients

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

The war against COVID-19: reinfection, vaccines, and herd immunity

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

Pets living in households with COVID-19 are high likely to seroconvert and become ill

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Nearly 60% of Americans infected by Omicron

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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