Infectious Diseases News and Research

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Immunomic Therapeutics initiates JRC-LAMP-vax vaccine Phase I trial in Sugi allergy

Immunomic Therapeutics, Inc., a leader in developing novel allergy immunotherapies, announced today that it has dosed the first patient in a Phase I clinical trial of its lead candidate, JRC-LAMP-vax vaccine, at its clinical site in Honolulu, Hawaii. Initial subjects include Japanese ex-patriates previously exposed to Japanese red cedar, or "Sugi," as it is known in Japan.

9 Nov 2012

Elevated ST2 biomarker levels strongly indicate heart failure and mortality in HIV patients

Critical Diagnostics, makers of the Presage ST2 Assay, announced today that during a presentation at the American Heart Association Scientific Sessions in Los Angeles, the results of a study demonstrated that elevated levels of the biomarker ST2 in HIV patients was strongly indicative of the development of heart failure and mortality.

9 Nov 2012

Soligenix receives FDA Fast Track designation for SGX203 to treat pediatric Crohn's disease

Soligenix, Inc., a development stage biopharmaceutical company, announced today that its program for development of SGX203 (oral beclomethasone 17,21-dipropionate or oral BDP) for the induction treatment of mild-to-moderate pediatric Crohn's disease has received "Fast Track" designation from the U.S. Food and Drug Administration (FDA).

8 Nov 2012

Antibiotic choices critical for elderly with bloodstream infections

Failure to treat patients with bacteremia with an appropriate antibiotic is particularly harmful in elderly patients, report researchers.

8 Nov 2012

Key areas of disease neglected by UK funding for infectious diseases

UK funding for infectious diseases research is neglecting some of the diseases that result in the highest rates of death and disability, according to an Article published Online First in The Lancet Infectious Diseases.

8 Nov 2012

Trauma transfusion ratios linked to survival

Transfusion practices significantly predict early inhospital mortality among adult trauma patients, suggests a report published in the Archives of Surgery.

8 Nov 2012

Study reveals increased risk of leukemia among Chernobyl cleanup workers

A 20-year study following 110,645 workers who helped clean up after the 1986 Chernobyl nuclear power plant accident in the former Soviet territory of Ukraine shows that the workers share a significant increased risk of developing leukemia. The results may help scientists better define cancer risk associated with low doses of radiation from medical diagnostic radiation procedures such as computed tomography scans and other sources.

8 Nov 2012

Two new EU Member States now represented within TRANSVAC services platform

In addition to the initial panel of nine services, the TRANSVAC transnational access platform has integrated in July 2012 five additional groups which provide their services to users on a free and paid basis. Two new European Union (EU) Member States are now represented within the platform of services: France and Portugal.

8 Nov 2012

London School of Hygiene & Tropical Medicine creates International Diagnostics Centre

Today sees the launch of the International Diagnostics Centre (IDC), a global research collaboration hub, created at the London School of Hygiene & Tropical Medicine to undertake innovative research on the development and deployment of new diagnostic tests that enable patients to be diagnosed faster, more accurately and cost effectively.

8 Nov 2012

HPV testing and cervical screening: an interview with Dr Rosa Legood

Human papillomavirus is a virus that is transmitted through sexual contact. In most cases the virus is transient and causes no harm, however in some cases it can go on to cause pre-cancer lesions and cervical cancer.

7 Nov 2012

Texas Biomed develops rapid, less expensive route to screen suitable tests for bioterror threats

Texas Biomedical Research Institute scientists in San Antonio have developed a faster, less expensive route to screen suitable tests for bioterror threats and accelerate the application of countermeasures.

7 Nov 2012

EPO provides notice of intent to issue European Patent Application for Aethlon Hemopurifier

Aethlon Medical, Inc., the pioneer in developing selective therapeutic filtration devices to address infectious disease, cancer and other life-threatening conditions, announced today that the European Patent Office (EPO) has provided the Company a notice of intent to issue European Patent Application No. 04 703 672.8 entitled "Method For Removal of Viruses From Blood By Lectin Affinity Hemodialysis."

7 Nov 2012

Loyola announces 2012 Junior and Senior Scientist of the Year during St. Albert's Day

Katherine L. Knight, PhD, one of the nation's leading immune system researchers, has been named 2012 Senior Scientist of the Year at Loyola University Chicago Stritch School of Medicine. Sakthivel Sadayappan, PhD, FAHA, who is doing groundbreaking research on a protein that is critical for the normal functioning of the heart, has been named 2012 Junior Scientist of the Year.

7 Nov 2012

Celldex to present results from CDX-301 Phase 1 study in healthy volunteers

Celldex Therapeutics, Inc. today announced an upcoming data presentation at the American Society of Hematology 54th Annual Meeting and Exposition to be held in Atlanta, GA from December 8 through December 11, 2012.

6 Nov 2012

Adenovirus detection not uncommon among children with Kawasaki disease

Clinicians should take caution when diagnosing a child who has a high fever and whose tests show evidence of adenovirus, and not assume the virus is responsible for Kawasaki-like symptoms. According to a new study from Nationwide Children's Hospital appearing in Clinical Infectious Diseases, adenovirus detection is not uncommon among children with Kawasaki disease.

5 Nov 2012

Round-the-clock ICU intensivists could reduce mortality rates, length of stay

Implementing 24-hour intensivists at medical intensive care units could reduce patient mortality rates, and significantly reduce patients' length of stay, indicate study results.

5 Nov 2012

Smoke-free laws lead to fewer heart attacks

A recent decline in the incidence of myocardial infarction in Olmsted County, Minnesota, USA, could be due to the implementation of smoke-free laws, researchers suggest.

5 Nov 2012

Imaging-based therapy benefits ‘wake-up stroke’ patients

Undertaking thrombolysis on the basis of magnetic resonance imaging findings in patients with stroke of unknown onset time may double their chances for a good outcome, say researchers.

5 Nov 2012

'Details of implementation' critical to reaching goal of AIDS-free generation

Noting the progress made since the beginning of the HIV/AIDS epidemic and the upcoming recognition of World AIDS Day on December 1, Ronald Valdiserri, deputy assistant secretary for health, infectious diseases at the Department of Health and Human Services, writes in a Public Health Reports opinion piece, "We would do well to keep in mind the following caution. No matter the elegance of the controlled trial, the statistical significance of the results, or the superiority of the science, we must confront this inevitable reality: We will never be able to take full advantage of our progress in HIV clinical and prevention science until we develop and sustain the human, organizational, and structural capacities necessary to implement these new scientific breakthroughs."

3 Nov 2012

Weill Cornell researchers awarded Grand Challenges Explorations grants

Weill Cornell Medical College announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

3 Nov 2012