Infectious Diseases News and Research

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Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

Sanofi presents overview of Phase II and III trials for quadrivalent influenza vaccine

Sanofi Pasteur, the vaccines division of Sanofi, presented today an overview of Phase II and Phase III clinical trials for its investigational quadrivalent influenza vaccine (QIV).

23 Oct 2012

'Fresher' blood transfusion does not mean better outcomes

Blood that has been stored for 2 weeks or more before being used in transfusions for critically ill patients does not appear to cause adverse effects, report US researchers.

22 Oct 2012

Mother–baby intensive care admission carries high mortality risk

Mothers and newborns who are both admitted to an intensive care unit are significantly more likely to die than mother–baby pairs who are not, a study suggests.

22 Oct 2012

PLoS ONE publishes review of AntiViral-HyperActivation Limiting Therapeutics clinical trial

ViroStatics, a private Italian/American biopharmaceutical company developing novel therapeutics for viral and other chronic diseases, announced that a review of the first human clinical trial to test a new class of anti-HIV medications known as AntiViral-HyperActivation Limiting Therapeutics (AV-HALTs) has been published in the peer-reviewed journal PLoS ONE.

22 Oct 2012

Researchers discover Hyalomma ticks in migratory birds

A type of haemorrhagic fever (Crimean-Congo) that is prevalent in Africa, Asia, and the Balkans has begun to spread to new areas in southern Europe. Now Swedish researchers have shown that migratory birds carrying ticks are the possible source of contagion.

22 Oct 2012

Microgravity and prolonged space flight could give unique advantages to germs

The cabin of a spacecraft halfway to Mars would be the least convenient place -- one cannot say "on earth" -- for a Salmonella or Pneumococcus outbreak, but a wide-ranging new paper suggests that microgravity and prolonged space flight could give unique advantages to germs.

22 Oct 2012

Mistakes are still commonly made in prescriptions of antiretroviral medications

Research presented at IDWeek 2012- concludes that despite advances in electronic medical records, mistakes are still commonly made in the prescription of antiretroviral medications for hospitalized HIV-positive patients. At the same time, a trio of studies suggests however, that electronic records in combination with increased clinical education can help to greatly decrease medical errors.

20 Oct 2012

MRSA-related pneumonia can be effectively treated in half the recommended time

The national practice guideline for treating MRSA-related pneumonia is seven to 21 days. A Henry Ford Hospital study found that effective treatment can be done in half the time.

20 Oct 2012

Henry Ford study evaluates length of treatment for MRSA-related pneumonia

The national practice guideline for treating MRSA-related pneumonia is seven to 21 days. A Henry Ford Hospital study found that effective treatment can be done in half the time.

20 Oct 2012

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers at the Salk Institute for Biological Studies have identified damage to neural stem cells as a powerful player in the disease.

20 Oct 2012

New data shows influenza-associated deaths among children, effectiveness of school vaccinations

New data being presented at IDWeek 2012TM shows the fatal risk that influenza poses even for children without underlying health conditions and the effectiveness of school-based vaccination programs in protecting student populations.

20 Oct 2012

Sanofi Pasteur files Fluzone sBLA with FDA for treatment of influenza

Sanofi Pasteur, the vaccines division of Sanofi, announced today that it has filed a Supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) for a quadrivalent formulation of its Fluzone (Influenza Virus Vaccine).

20 Oct 2012

Novel therapy that uses human stool is safe and highly effective in treating C.diff infection

A novel therapy that uses donated human stool to treat the deadly and contagious C.diff infection is safe and highly effective, according to a Henry Ford Hospital study.

20 Oct 2012

Link between norovirus outbreaks and excess hospitalization and mortality in nursing homes

In a study that included more than 300 Medicare-certified nursing homes, rates of hospitalization and death were substantially increased during outbreaks of norovirus gastroenteritis vs. non-outbreak periods, according to a study appearing in the October 24/31 issue of JAMA.

19 Oct 2012

Linezolid proves effective in treating drug-resistant TB

When tested in patients hospitalized with extensively drug-resistant tuberculosis (XDR-TB) unresponsive to previous treatment, linezolid, an antibiotic used to treat severe bacterial infections, proved largely effective when added to the patients' ongoing TB treatment regimen.

19 Oct 2012

Lupus investigators receive LRI's first $1 million research grants

The Lupus Research Institute (LRI) today announced the first $1 million research grants given to lupus investigators by a private research organization.

19 Oct 2012

Number of new TB infections fall, but drug resistance, lack of funding could slow progress, WHO reports

"New tuberculosis [TB] infections dropped 2.2 percent worldwide last year, but with nearly nine million new infections, the World Health Organization said TB remains a massive problem that could worsen if countries shortchange funding to fight it," Reuters reports.

19 Oct 2012

TB Alliance and FIND partner to promote development of TB drugs and diagnostics

A new partnership announced today will increase efforts to coordinate the development of complementary novel tools to fight TB, including drug-resistant TB, and identify emerging drug resistance trends around the globe.

19 Oct 2012

Chloride-restrictive intravenous fluids reduce risk for kidney injury

The restrictive use of chloride in intravenous fluids reduces the risk for acute kidney injury and renal replacement therapy, research shows.

18 Oct 2012

Infectious Diseases News and Research

Glioblastoma multiforme can originate from cortical neurons

Sanofi presents overview of Phase II and III trials for quadrivalent influenza vaccine

'Fresher' blood transfusion does not mean better outcomes

Mother–baby intensive care admission carries high mortality risk

PLoS ONE publishes review of AntiViral-HyperActivation Limiting Therapeutics clinical trial

Researchers discover Hyalomma ticks in migratory birds

Microgravity and prolonged space flight could give unique advantages to germs

Mistakes are still commonly made in prescriptions of antiretroviral medications

MRSA-related pneumonia can be effectively treated in half the recommended time

Henry Ford study evaluates length of treatment for MRSA-related pneumonia

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

New data shows influenza-associated deaths among children, effectiveness of school vaccinations

Sanofi Pasteur files Fluzone sBLA with FDA for treatment of influenza

Novel therapy that uses human stool is safe and highly effective in treating C.diff infection

Link between norovirus outbreaks and excess hospitalization and mortality in nursing homes

Linezolid proves effective in treating drug-resistant TB

Lupus investigators receive LRI's first $1 million research grants

Number of new TB infections fall, but drug resistance, lack of funding could slow progress, WHO reports

TB Alliance and FIND partner to promote development of TB drugs and diagnostics

Chloride-restrictive intravenous fluids reduce risk for kidney injury

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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