Insulin Resistance News and Research RSS Feed - Insulin Resistance News and Research

Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.
New research shows that serious life events in childhood can increase type 1 diabetes risk

New research shows that serious life events in childhood can increase type 1 diabetes risk

New research from Sweden published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that serious life events (SLEs) in childhood, such as death or illness in the family, divorce/separation, a new child or adult in the family, and conflicts in the family, can triple the risk of subsequently developing type 1 diabetes (T1D). [More]
Remogliflozin etabonate: A potential treatment option for management of NASH and NAFLD

Remogliflozin etabonate: A potential treatment option for management of NASH and NAFLD

Data presented today at The International Liver Congress 2015 demonstrates that remogliflozin etabonate, an investigational drug in type 2 diabetes, is a potential treatment option for the management of patients with non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD). [More]
New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins. [More]
High-fat diet can alter your muscle metabolism, new study finds

High-fat diet can alter your muscle metabolism, new study finds

You might think that you can get away with eating fatty foods for a few days without it making any significant changes to your body. Think again. After just five days of eating a high-fat diet, the way in which the body's muscle processes nutrients changes, which could lead to long-term problems such as weight gain, obesity, and other health issues, a new study has found. [More]
Study identifies gut immune system as new, effective target for diabetes

Study identifies gut immune system as new, effective target for diabetes

A commonly-used drug to treat inflammatory bowel disease, such as Crohn's disease, has been shown to lower blood sugar levels in obese mice, potentially identifying the gut immune system as a new and effective target in treating diabetes in humans. [More]
FGF21 protein can boost regenerative effects of human PPARα

FGF21 protein can boost regenerative effects of human PPARα

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα is far more active and efficient than the human form, allowing mice to quickly regenerate damaged livers. [More]
Anti-diabetic medication activates brain sensors, promotes weight gain

Anti-diabetic medication activates brain sensors, promotes weight gain

Medication used to treat patients with type II diabetes activates sensors on brain cells that increase hunger, causing people taking this drug to gain more body fat, according to researchers at Georgia State University, Oregon Health and Science University, Georgia Regents University and Charlie Norwood Veterans Administration Medical Center. [More]
GFT505 demonstrates dose-dependent efficacy on primary endpoint in phase 2 NASH trial

GFT505 demonstrates dose-dependent efficacy on primary endpoint in phase 2 NASH trial

GENFIT, today announces topline results of the phase 2 GOLDEN-505 trial in NASH. Due to the unexpected rate of resolution of NASH in patients randomized to placebo who had early NASH (NAS of 3, placebo response rate>57%), along with the high number of sites for a limited sample size, the study as initially designed did not enable the trial to meet directly the primary endpoint. [More]
Study finds clustered cardiometabolic risk factors in children

Study finds clustered cardiometabolic risk factors in children

Lifestyle-related cardiometabolic risk factors cluster already in children in the same way as in adults, according to research from the University of Eastern Finland. A cardiometabolic risk score was used to evaluate cardiometabolic risk in different age groups. [More]
Plexin D1 gene determines body fat distribution in humans

Plexin D1 gene determines body fat distribution in humans

Scientists have known for some time that people who carry a lot of weight around their bellies are more likely to develop diabetes and heart disease than those who have bigger hips and thighs. [More]
Vitamin D3 and metformin show promising results in preventing colorectal cancer

Vitamin D3 and metformin show promising results in preventing colorectal cancer

The concept was simple: If two compounds each individually show promise in preventing colon cancer, surely it's worth trying the two together to see if even greater impact is possible. [More]
Vitamin D plays major role in preventing diabetes and atherosclerosis

Vitamin D plays major role in preventing diabetes and atherosclerosis

In recent years, a deficiency of vitamin D has been linked to type 2 diabetes and heart disease, two illnesses that commonly occur together and are the most common cause of illness and death in Western countries. Both disorders are rooted in chronic inflammation, which leads to insulin resistance and the buildup of artery-clogging plaque. [More]
Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Scientists at Institut Cochin (CNRS/Inserm/Université Paris Descartes) and ICAN - Institute of Cardiometabolism And NutritionInserm/UPMC/AP-HP) have discovered that a class of inflammatory cells, MAIT lymphocytes1, is deregulated in patients suffering from type 2 diabetes and obesity. [More]
Mother's age at childbirth may affect metabolic health of male children

Mother's age at childbirth may affect metabolic health of male children

A mother's age at childbirth may affect her male baby's birth weight as well as his adult glucose metabolism, new research shows. [More]
Testosterone, estrogen raise men's risk of heart disease

Testosterone, estrogen raise men's risk of heart disease

Why men have more heart disease than premenopausal women has been unclear, but a new study shows that the sex hormones testosterone and estrogen alter cardiovascular risk factors in a way that raises a man's risk of heart disease. [More]
Obese females with eating/behavioral characteristic have impaired metabolism

Obese females with eating/behavioral characteristic have impaired metabolism

In obese females, a close relationship may exist between their disinhibition (detrimental eating and behavioral characteristics) that limits successful weight loss, and impaired metabolism, new research shows. [More]
People who quit smoking have improved metabolic effects, new study finds

People who quit smoking have improved metabolic effects, new study finds

People who quit smoking have improved metabolic effects, a new study finds. The results will be presented in a poster Thursday, March 5, at ENDO 2015, the annual meeting of the Endocrine Society in San Diego. [More]
Even 30 minutes of sleep debt per day can promote obesity and insulin resistance

Even 30 minutes of sleep debt per day can promote obesity and insulin resistance

Losing as little as 30 minutes of sleep per day on weekdays can have long-term consequences for body weight and metabolism, a new study finds. The results will be presented Thursday, March 5, at ENDO 2015, the annual meeting of the Endocrine Society in San Diego. [More]
MBSR reduces fasting glucose, improves quality of life in overweight and obese women

MBSR reduces fasting glucose, improves quality of life in overweight and obese women

A treatment known as mindfulness-based stress reduction (MBSR) may decrease fasting glucose and improve quality of life in overweight and obese women, new research suggests. [More]
Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

A new soybean oil genetically modified to be healthier than conventional soybean oil causes obesity, pre-diabetes and fatty liver in a nearly identical manner to that of regular soybean oil when part of a typical American high-fat diet, an animal study shows. [More]
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