Insulin Resistance News and Research RSS Feed - Insulin Resistance News and Research

Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.
Vascular and Alzheimer's-related brain abnormalities cause dementia in older people

Vascular and Alzheimer's-related brain abnormalities cause dementia in older people

A growing body of research suggests that the most common cause of dementia in older people is a mix of vascular and Alzheimer's-related brain abnormalities, and that approximately half of people who die with Alzheimer's also have evidence of strokes in their brains. Furthermore, when strokes and hallmark Alzheimer's plaques and tangles are combined, it increases a person's likelihood of experiencing dementia. [More]
U-M researchers identify how amlexanox drug improves metabolism of sugar

U-M researchers identify how amlexanox drug improves metabolism of sugar

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver. [More]
Pellino3 protein may prevent obesity-driven diabetes, find Maynooth University scientists

Pellino3 protein may prevent obesity-driven diabetes, find Maynooth University scientists

Maynooth University scientists have identified a protein in the body that may have the potential to prevent the development of obesity-driven diabetes. [More]
Stress can trigger diabetes, depression and other autoimmune diseases

Stress can trigger diabetes, depression and other autoimmune diseases

Stress is an ability of humans to fight or flee when faced with problems affecting the individual. By changes in the organism, adaptation to various physical conditions is achieved: burns, bruises, bleeding or psychosocial traumas. [More]
Fat cells below skin help protect from bacteria, say researchers

Fat cells below skin help protect from bacteria, say researchers

When it comes to skin infections, a healthy and robust immune response may depend greatly upon what lies beneath. In a new paper published in the January 2, 2015 issue of Science, researchers at the University of California, San Diego School of Medicine report the surprising discovery that fat cells below the skin help protect us from bacteria. [More]
Study: Low glycemic diet does not improve insulin sensitivity or cardiovascular risk factors

Study: Low glycemic diet does not improve insulin sensitivity or cardiovascular risk factors

Nutrition experts are continually debating the nutritional value of carbohydrate-containing foods and whether some are healthier than others. High carbohydrate foods are classified by how much they increase blood sugar; known as glycemic index. In new findings led by researchers at Brigham and Women's Hospital in Boston and Johns Hopkins University in Baltimore, researchers looked at glycemic index' effect on cardiovascular disease (CVD) and diabetes and found that low glycemic diets did not improve insulin sensitivity or cardiovascular risk factors. [More]
New study finds that immune cells in the brain may contribute to obesity

New study finds that immune cells in the brain may contribute to obesity

Immune cells perform a previously unsuspected role in the brain that may contribute to obesity, according to a new study by UC San Francisco researchers. [More]
UR researchers on track to solve mystery of weight gain

UR researchers on track to solve mystery of weight gain

University of Rochester researchers believe they're on track to solve the mystery of weight gain - and it has nothing to do with indulging in holiday eggnog. [More]
Weight-loss surgery may reduce lower urinary tract symptoms

Weight-loss surgery may reduce lower urinary tract symptoms

Metabolic syndrome is linked with an increased frequency and severity of lower urinary tract symptoms, but weight loss surgery may lessen these symptoms. The findings, which come from two studies published in BJU International, indicate that urinary problems may be added to the list of issues that can improve with efforts that address altered metabolism. [More]
Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Type 1 diabetes is a complex condition to manage. It requires continuous, around the clock monitoring of blood glucose levels, which change repeatedly throughout the day and night. [More]
New research suggests potential role for MEK inhibitors in type 2 diabetes

New research suggests potential role for MEK inhibitors in type 2 diabetes

A research team led by Brigham and Women's Hospital and Dana-Farber Cancer Institute has uncovered surprising new findings that underscore the role of an important signaling pathway, already known to be critical in cancer, in the development of type 2 diabetes. [More]
Chemical compound in coffee may help prevent damaging effects of obesity

Chemical compound in coffee may help prevent damaging effects of obesity

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. [More]
IU School of Medicine researchers identify new protein that can control diabetes

IU School of Medicine researchers identify new protein that can control diabetes

Indiana University School of Medicine researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity. [More]
Light-activated diabetes drug: an interview with Dr David Hodson

Light-activated diabetes drug: an interview with Dr David Hodson

We've known about chemicals that can be light-activated for about five to ten years now. They’ve mainly all been applied to neurons and, more specifically, the retina. Nobody has ever really looked at any tissues outside of the nervous system. [More]
UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease. [More]
Insulin resistance linked to treatment-refractory bipolar disorder

Insulin resistance linked to treatment-refractory bipolar disorder

Patients with bipolar disorder who are insulin resistant are likely to also be refractory to mood-stabilising treatment, report researchers. [More]
Research: MHCI protein moonlights in nervous system to regulate synapses

Research: MHCI protein moonlights in nervous system to regulate synapses

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function. [More]
Researchers propose new milestones to augment National Alzheimer's Plan

Researchers propose new milestones to augment National Alzheimer's Plan

The U.S. Government has initiated a major effort to prevent and effectively treat Alzheimer's disease by 2025. However, a workgroup of nearly 40 Alzheimer's researchers and scientists says the research milestones in the U.S. Government's National Plan to Address Alzheimer's Disease must be broadened in scope, increased in scale, and adequately funded in order to successfully achieve this goal. [More]
Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

A University of Utah-led study using X-rays and neutron beams has revealed the inner workings of a master switch that regulates basic cellular functions, but that also, when mutated, contributes to cancer, cardiovascular disease and other deadly disorders. [More]
Obesity greatly accelerates aging of the liver

Obesity greatly accelerates aging of the liver

Using a recently developed biomarker of aging known as an epigenetic clock, UCLA researchers working closely with a German team of investigators have found for the first time that obesity greatly accelerates aging of the liver. This finding could explain the early onset of many age-related diseases, including liver cancer, in obese subjects [More]