Insulin Resistance News and Research RSS Feed - Insulin Resistance News and Research

Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.
Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

In the first study to investigate blood lipid levels in association with consumption of sugar-sweetened beverages (SSBs) in a racially and ethnically diverse sample of Boston area schoolchildren, researchers found there was an inverse association between SSB intake changes and HDL-cholesterol increases (HDL-C is the "good cholesterol"). [More]
Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

Virginia Tech researchers have identified a biomarker in pre-diabetic individuals that could help prevent them from developing Type II diabetes. [More]
New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935. [More]
Discovery could influence future research on respiratory failure associated with diabetes

Discovery could influence future research on respiratory failure associated with diabetes

Previous studies have shown that diabetes adversely affects breathing and respiratory function. However, in the past, researchers have not differentiated diaphragm muscle cells and the muscle cells of limb skeletal muscle in their studies. Now, researchers from the University of Missouri have found that diaphragm muscle cells and other skeletal muscle cells behave differently--a finding that could influence future research on respiratory ailments associated with diabetes. [More]
FSU study reveals new method for treating diabetes

FSU study reveals new method for treating diabetes

A new Florida State University study is changing how researchers look at diabetes research and the drugs used to treat the disease. [More]
Muscle mass appears to ward off bad cardiovascular effects of obesity

Muscle mass appears to ward off bad cardiovascular effects of obesity

Even without losing fat, more muscle appears to go a long way in fighting off the bad cardiovascular effects of obesity. That emerging evidence has scientists looking hard for new targets to uncouple the unhealthy relationship between fat and cardiovascular disease. [More]
Inflammation from diets deficient in nutrients contribute to weight despite intake of macronutrients

Inflammation from diets deficient in nutrients contribute to weight despite intake of macronutrients

If you are watching what you eat, working out, and still not seeing improvements in your cholesterol, blood pressure, blood sugar, etc., here's some hope. A new report appearing in the August 2015 issue of The FASEB Journal suggests that inflammation induced by deficiencies in vitamins and minerals might be the culprit. [More]
Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015. [More]
NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

Isis Pharmaceuticals, Inc., the leader in RNA-targeted therapeutics, and Akcea Therapeutics, its wholly owned subsidiary, announced today that The New England Journal of Medicine (NEJM) has published positive clinical results from a Phase 2 clinical study evaluating volanesorsen (formerly ISIS-APOCIII Rx) in patients with very high to severely high triglycerides. [More]
New Iowa State study finds strong link between insulin resistance and increased Alzheimer's disease risk

New Iowa State study finds strong link between insulin resistance and increased Alzheimer's disease risk

The fact that obesity increases the risk of cardiovascular disease and some cancers is well known. But a new Iowa State University study adds to the growing evidence that memory loss should also be a top concern. [More]
Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards. [More]
Study shows glitazone antidiabetic drug may reduce risk of Parkinson’s disease

Study shows glitazone antidiabetic drug may reduce risk of Parkinson’s disease

A type of drug used to treat diabetes may reduce the risk of developing Parkinson’s disease, according to a new study published in PLOS Medicine. [More]
UT Southwestern researchers find potential therapy to treat diabetes, nonalcoholic fatty liver disease

UT Southwestern researchers find potential therapy to treat diabetes, nonalcoholic fatty liver disease

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, UT Southwestern Medical Center diabetes researchers have found. [More]
Genetic mutation associated with severe loss of body fat, appearance of premature aging in children identified

Genetic mutation associated with severe loss of body fat, appearance of premature aging in children identified

Researchers at the Translational Genomics Research Institute have identified a genetic mutation associated with the appearance of premature aging and severe loss of body fat in children. [More]
Middle classes from developing countries more vulnerable to develop diabetes due ancestral diets

Middle classes from developing countries more vulnerable to develop diabetes due ancestral diets

The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today's changing environment. New research published today in Cell Metabolism from the University of Sydney in Australia, the National Centre for Cell Science and the DYP Medical College in Pune, India reveals this may be a result of the nutrition endured by their ancestors. [More]
Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

According to a new series of studies out of NYU Langone Medical Center, two chemicals increasingly used during manufacturing to strengthen plastic wrap, soap, cosmetics, and processed food containers have been linked to a rise in risk of high blood pressure and diabetes in children and adolescents. [More]
Researchers pinpoint two biomarkers elevated in severe form of coronary disease

Researchers pinpoint two biomarkers elevated in severe form of coronary disease

Insulin resistance affects tens of millions of Americans and is a big risk factor for heart disease. Yet, some people with the condition never develop heart disease, while some experience moderate coronary blockages. Others, though, get severe atherosclerosis - multiple blockages and deterioration of coronary arteries characterized by thick, hard, plaque-ridden arterial walls. [More]
Akcea Therapeutics obtains FDA Orphan Drug Designation for volanesorsen

Akcea Therapeutics obtains FDA Orphan Drug Designation for volanesorsen

Akcea Therapeutics, a wholly-owned subsidiary of Isis Pharmaceuticals, Inc., announced today that the U.S. Food and Drug Administration has granted Orphan Drug Designation to volanesorsen (ISIS-APOCIIIRx) for the treatment of patients with Familial Chylomicronemia Syndrome (FCS). [More]
Researchers analyze cardiometabolic benefits of exercise

Researchers analyze cardiometabolic benefits of exercise

Everyone knows that exercise generally helps the cardiovascular system, but much remains unknown about how the benefits arise, and what to expect in different people who exercise to improve their health. To gain a more precise understanding of how exercise improves health and whom it helps most, researchers analyzed the results of 160 randomized clinical trials with nearly 7,500 participants. [More]
Tree nut consumption associated with lower body weight and lower risk of obesity

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022). [More]
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