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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.
Study links low- and high-birthweight babies to increased cardiovascular disease risk

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University. [More]
Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life. [More]
Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. [More]
TAK1 deficit protects mice from obesity

TAK1 deficit protects mice from obesity

Obesity and subsequent complications are increasing in frequency worldwide. The accumulation of adipose tissue is associated with increased inflammation, and it has been proposed that modification of proinflammatory responses could alter adipose tissue composition. [More]
Exposure to bright light may influence metabolism

Exposure to bright light may influence metabolism

Exposure to bright light could affect your metabolism, reports a new Northwestern Medicine study. [More]
Combination of two compounds found in red grapes, oranges could treat diseases

Combination of two compounds found in red grapes, oranges could treat diseases

A combination of two compounds found in red grapes and oranges could be used to improve the health of people with diabetes, and reduce cases of obesity and heart disease. [More]
Oral regimens could offer simple solution for severe hyperglycaemia

Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes. [More]
Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found. [More]
Southern Society bestows 2016 Clinical Science Young Investigator Award to Stansfield

Southern Society bestows 2016 Clinical Science Young Investigator Award to Stansfield

Dr. Brian K. Stansfield, neonatologist at Children's Hospital of Georgia and a 2004 graduate of the Medical College of Georgia at Augusta University, has received the 2016 Clinical Science Young Investigator Award from the Southern Society for Pediatric Research. [More]
Daily chocolate consumption may improve cardio-metabolic health

Daily chocolate consumption may improve cardio-metabolic health

A new study published in the British Journal of Nutrition appears to back up the adage that a little of what you fancy does you good. [More]
Study reveals how visceral fat contributes to insulin resistance, inflammation

Study reveals how visceral fat contributes to insulin resistance, inflammation

Researchers have long-known that visceral fat - the kind that wraps around the internal organs - is more dangerous than subcutaneous fat that lies just under the skin around the belly, thighs and rear. But how visceral fat contributes to insulin resistance and inflammation has remained unknown. [More]
High fructose consumption during pregnancy may increase risk factors for heart disease in children

High fructose consumption during pregnancy may increase risk factors for heart disease in children

The negative health effects of consuming large amounts of fructose could impact several generations, according to researchers at The University of Texas Medical Branch at Galveston. [More]
Specific intake levels of xanthohumol reduces obesity, cholesterol and elevated glucose

Specific intake levels of xanthohumol reduces obesity, cholesterol and elevated glucose

A recent study at Oregon State University has identified specific intake levels of xanthohumol, a natural flavonoid found in hops, that significantly improved some of the underlying markers of metabolic syndrome in laboratory animals and also reduced weight gain. [More]
Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

A nationwide study of 2.3 million Israeli adolescents, examined from 1967 through 2010, finds an association between elevated body-mass index in late adolescence, and subsequent cardiovascular mortality in midlife. [More]
Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

In a new study, published in the online edition of the journal EBioMedicine, a multi-disciplinary team led by researchers at University of California, San Diego School of Medicine has identified key inflammatory mechanisms underlying type 1 diabetes and obesity-related kidney dysfunction. [More]
Infant daughters may show early signs of PCOS from mothers

Infant daughters may show early signs of PCOS from mothers

The infant daughters of women with polycystic ovary syndrome (PCOS) show a higher level of an enzyme that activates testosterone and may be an early sign of developing the complex genetic disease, according to a new Northwestern Medicine study. [More]
Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

In obesity, the body's immune system can treat tissues as if they are suffering from a low-grade chronic infection. This obesity-induced inflammation is an important contributor to insulin resistance, a condition that can progress into type 2 diabetes. [More]
Lund researchers discover new biomarker that can predict type 2 diabetes risk

Lund researchers discover new biomarker that can predict type 2 diabetes risk

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. The results are published today in Nature Communications. [More]
Gleevec could be novel therapeutic agent for type 2 diabetes

Gleevec could be novel therapeutic agent for type 2 diabetes

The cancer treatment drug Imatinib, otherwise known as Gleevec is approved to treat various forms of cancer, mostly notably chronic myeloid leukemia (CML). However, researchers have stumbled onto another possible use for it, curing type 2 diabetes. [More]
Hands-on workshop reviews literature on body weight, oral health

Hands-on workshop reviews literature on body weight, oral health

A hands-on workshop titled "Documenting Obesity and Underweight in Clinical Dental Settings" will take place today at the 45th Annual Meeting & Exhibition of the American Association for Dental Research. The AADR Annual Meeting is being held in conjunction with the 40th Annual Meeting of the Canadian Association for Dental Research. [More]
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