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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.
Rat study finds maternal intake of oxidised fish oil causes high newborn mortality

Rat study finds maternal intake of oxidised fish oil causes high newborn mortality

Nearly 30 percent of newborn pups born to pregnant rats fed highly oxidized ("off") fish oil died within two days after birth a new study by researchers at the Liggins Institute at the University of Auckland in New Zealand finds. [More]
Breastfeeding leads to long-term metabolic changes in mothers, study shows

Breastfeeding leads to long-term metabolic changes in mothers, study shows

An interdisciplinary team of scientists at the Helmholtz Zentrum München has studied the metabolism of women with gestational diabetes after giving birth. [More]
Eating more healthy fats may lower type 2 diabetes risk

Eating more healthy fats may lower type 2 diabetes risk

Eating more unsaturated fats, especially polyunsaturated fats, in place of either dietary carbohydrate or saturated fats lowers blood sugar levels and improves insulin resistance and secretion, according to a new meta-analysis of data from 102 randomised controlled feeding trials in adults. [More]
Obesity is linked with premature death, particularly in men

Obesity is linked with premature death, particularly in men

Being overweight or obese is associated with an increased risk of premature death, according to the largest ever study into obesity and death. [More]
Changes in cavefish metabolism could lead to new insights into diabetes

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems. [More]
CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

Non-alcoholic steatohepatitis (NASH) is a serious hepatic condition that precedes hepatocellular carcinoma (HCC) and is currently untreatable. [More]
New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss. [More]
Study links proteins involved in cell division to insulin signaling

Study links proteins involved in cell division to insulin signaling

Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, UT Southwestern Medical Center researchers have found. [More]
Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others. [More]
Blood mannose levels could help predict type 2 diabetes risk

Blood mannose levels could help predict type 2 diabetes risk

Even if you are not overweight, your mannose levels may indicate whether you're at risk for type 2 diabetes (T2D) or insulin resistance (IR), a Swedish study shows. [More]
Latest online version of German Diabetes Risk Score optimized for mobile devices

Latest online version of German Diabetes Risk Score optimized for mobile devices

The German Institute of Human Nutrition has updated the online version of its German Diabetes Risk Score and has optimized it for mobile devices. [More]
SORLA protein makes fat cells oversensitive to insulin

SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease. [More]
Mother's obesity can impair health of future generations

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets. [More]
Brain's reward system in obese people operates differently in response to food and dopamine

Brain's reward system in obese people operates differently in response to food and dopamine

As young people reach adulthood, their preferences for sweet foods typically decline. But for people with obesity, new research suggests that the drop-off may not be as steep and that the brain's reward system operates differently in obese people than in thinner people, which may play a role in this phenomenon. [More]
Nut consumption may lower risk of overall mortality in prostate cancer patients

Nut consumption may lower risk of overall mortality in prostate cancer patients

In a large prospective study published online in the British Journal of Cancer, researchers looked at the association between nut consumption and prostate cancer risk and mortality among 47,299 men in the Health Professionals Follow-up Study. [More]
MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

The so-called artificial pancreas — an automated insulin delivery system for people with type 1 diabetes mellitus — uses an advanced control algorithm to regulate how much insulin a pump should deliver and when. Regulating glucose is challenging because levels respond to a wide-array of variables, including food, physical activity, sleep, stress, hormones, metabolism and more. [More]
Epigenomic alterations play key role in triggering obesity-induced diabetes

Epigenomic alterations play key role in triggering obesity-induced diabetes

Obesity is a risk factor for developing type 2 diabetes, yet not all obese humans develop the disease. In a new study, researchers from the Karolinska Institutet in Sweden and from the Institute of Health and Medical Research in France have identified epigenomic alterations that are associated with inflammation and type 2 diabetes [More]
Study links low- and high-birthweight babies to increased cardiovascular disease risk

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University. [More]
Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life. [More]
Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. [More]
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