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Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

IU’s environmental expert addresses plan to fight Lyme disease, other tick-borne illnesses

On May 23, a bill to address increased incidence of Lyme disease and other tick-borne diseases in the United States was introduced in the US Senate.

31 May 2019

Novel chemical probe enables live imaging of brain immune cells

Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain.

3 May 2019

Finnish researchers discover gene mutation that reduces fear, anxiety and increases social interaction

Finnish researchers at the University of Eastern Finland and the University of Oulu have discovered of a new type of gene mutation that reduces fear and anxiety, and increases social interaction.

3 May 2019

Regular endurance exercise leads to high Nrf2 nuclear translocation, DNA binding activity

Skeletal muscle mass and function becomes progressively compromised with aging, chronic disease, and physical inactivity.

26 Apr 2019

Scientists discover trigger region for absence epileptic seizures

Scientists have discovered a neurological origin for absence seizures--a type of seizure characterized by very short periods of lost consciousness in which people appear to stare blankly at nothing.

25 Apr 2019

Two proteins act in concert to maintain a healthy heart in mice, shows study

Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators.

17 Apr 2019

Growth hormone acts directly on the brain to conserve energy when the body loses weight

Researchers at the University of São Paulo in Brazil have discovered that growth hormone (GH), which stimulates skeletal maturation and linear bone growth, as well as helping maintain tissue and organs throughout life, also acts directly on the brain to conserve energy when the body loses weight.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

Researchers find presence of Aire gene in lymph nodes

The thymus is the organ in which T cells differentiate. T cells express various T cell receptors for reacting with various pathogenic microbes and viruses.

11 Apr 2019

Research uncovers crucial receptor involved in response to fast-acting antidepressants

Effective treatment of clinical depression remains a major mental health issue, with roughly 30 percent of patients who do not respond to any of the available treatments.

29 Mar 2019

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability.

28 Mar 2019

Surprising discovery offers clues to limit graft-vs.-host disease

A protein that protects people with inflammatory bowel disease has quite a different effect in graft-vs.-host disease, a common and challenging side effect of bone marrow transplants.

22 Mar 2019

Roundworm study suggests alternatives for treatment of schizophrenia

A group of Brazilian scientists have long conducted experiments with roundworms to investigate the role of schizophrenia-linked genes in patients' response to antipsychotic drugs. The results obtained thus far point to new ways of understanding resistance to certain classes of medication.

20 Mar 2019

Study reveals how a regulatory molecule ensures appropriate supply of blood cells

The body needs to create a continuous supply of blood cells to enter circulation. Blood cells have a wide variety of functions ranging from supplying oxygen to tissues, fighting infections, and enabling the blood to clot upon injury.

13 Mar 2019

Absence of crucial protein may lead to rapid, severe bone loss

The absence of a protein critical to the control of inflammation may lead to rapid and severe bone loss, according to a new University at Buffalo study.

12 Mar 2019

Second man cured of HIV

A London is now free of HIV/AIDS after a stem cell transplant therapy. This is the second such case after the first case of cured HIV in Berlin.

5 Mar 2019

Study elucidates mechanism behind development of steroid diabetes

Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout the body, how these adverse effects are caused and by which organ are not well understood.

28 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019