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Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with tAUCB (trans-4-(4-[3-adamantan-1-yl-ureid]-cyclohexyloxy)-benzoic acid) and activating peroxisome proliferator-activator receptorγ (PPARγ) with the thiazolidinedione rosiglitazone on the pathological progression of cardiometabolic syndrome.

25 Apr 2013

New antimicrobial agents do not rely on traditional antibiotics

In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not rely on traditional antibiotics.

25 Apr 2013

Scientists report loss of dental material may be linked to reduction of tooth wear

Scientists of the Max Planck Institute for Evolutionary Anthropology in Leipzig and the Senckenberg Research Institute in Frankfurt together with dental technicians have digitally analysed modern human teeth using an engineering approach, finite element method, to evaluate the biomechanical behaviour of teeth under realistic loading.

25 Apr 2013

Transvaginal sonography: Best diagnostic method for evaluating suspected ectopic pregnancy

For women with abdominal pain or vaginal bleeding during early pregnancy, patient history and clinical examination alone are insufficient to indicate or eliminate the possibility of ectopic pregnancy, while transvaginal sonography appears to be the single best diagnostic method for evaluating suspected ectopic pregnancy, according to an analysis of previous studies reported in the April 24 issue of JAMA.

25 Apr 2013

Mechanism of tumor suppressor p53 inactivation described

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond repair. Not surprisingly, p53’s critical function is disrupted in most cancers.

25 Apr 2013

Chinese bird flu continues to spread

The H7N9 avian influenza outbreak in China is continuing to spread, although authorities believe that the large majority of those affected did not become infected via human-to-human contact.

25 Apr 2013

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them.

25 Apr 2013

FDA announces public-private partnership to identify counterfeit anti-malarial medicines with CD-3

The U.S. Food and Drug Administration today announced a public-private partnership to help identify counterfeit or substandard anti-malarial medicines, including falsified products, with the deployment of the FDA-developed Counterfeit Detection Device, called CD-3.

25 Apr 2013

Dietary substitution of saturated fats enriched in MCT prevents liver disease

Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin Ronis have determined that dietary substitution of saturated fats enriched in medium chain triglycerides (MCT) for polyunsaturated fat prevents the development of nonalcoholic fatty liver disease (NAFLD).

25 Apr 2013

Astrocytes more effective in promoting recovery after brain injury

The production of a certain kind of brain cell that had been considered an impediment to healing may actually be needed to staunch bleeding and promote repair after a stroke or head trauma, researchers at Duke Medicine report.

25 Apr 2013

Symposium presentation highlights pioneer of gastrointestinal research

A fur trader who suffered an accidental gunshot wound in 1822 and the physician who saw this unfortunate incidence as an opportunity for research are key to much of our early knowledge about the workings of the digestive system, say speakers of an upcoming symposium.

25 Apr 2013

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

With the help of genetics, prostate specific antigen screenings may become more accurate and reduce the number of unnecessary prostate biopsies, according to a new study from Northwestern Medicine.

25 Apr 2013

Cultivation of legumes helps farmers add natural nitrogen to agricultural fields

The overuse of nitrogen fertilizers in agriculture can wreak havoc on waterways, health and the environment.

25 Apr 2013

Promising development for women with triple-negative breast cancer

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary activities so that it might work on more aggressive breast cancer.

24 Apr 2013

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Rheumatoid arthritis (RA) is an autoimmune disorder that can cause debilitating joint damage. In cases of RA, the immune system attacks the body’s own tissues, especially the membranes that line the joints. As a result, fluid builds up in the joints, causing pain and systemic inflammation, leading to joint destruction if untreated.

From Quest Diagnostics 23 Apr 2013

Drug delivery system discussions between mPhase Technologies, Inc. and major European Drug Company

mPhase Technologies, Inc. (OTCBB: XDSL) reported today that it has commenced the discussion of its drug delivery system with a major European Drug Company. The discussions were arranged through mPhase's continuing relationship with Invest In France, an agency of the French government.

23 Apr 2013

Animal models of Huntington's disease allow better insights into disease's genetics

Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology.

23 Apr 2013

Research: Skin's immune cell plays a role in fighting off parasitic invaders

Sydney researchers have discovered a new type of immune cell in skin that plays a role in fighting off parasitic invaders such as ticks, mites, and worms, and could be linked to eczema and allergic skin diseases.

23 Apr 2013

RUSM students to perform clinical training at Vanguard MacNeal Hospital

Ross University School of Medicine announced an agreement with Vanguard MacNeal Hospital in Berwyn, Ill. which enables RUSM students to perform clinical training in the Chicago-area teaching hospital.

23 Apr 2013

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

23 Apr 2013

Laboratory News and Research

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

New antimicrobial agents do not rely on traditional antibiotics

Scientists report loss of dental material may be linked to reduction of tooth wear

Transvaginal sonography: Best diagnostic method for evaluating suspected ectopic pregnancy

Mechanism of tumor suppressor p53 inactivation described

Chinese bird flu continues to spread

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

FDA announces public-private partnership to identify counterfeit anti-malarial medicines with CD-3

Dietary substitution of saturated fats enriched in MCT prevents liver disease

Astrocytes more effective in promoting recovery after brain injury

Symposium presentation highlights pioneer of gastrointestinal research

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

Cultivation of legumes helps farmers add natural nitrogen to agricultural fields

Promising development for women with triple-negative breast cancer

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Drug delivery system discussions between mPhase Technologies, Inc. and major European Drug Company

Animal models of Huntington's disease allow better insights into disease's genetics

Research: Skin's immune cell plays a role in fighting off parasitic invaders

RUSM students to perform clinical training at Vanguard MacNeal Hospital

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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