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Australian, Singapore researchers join hands to combat disease-causing bugs

The fight against a number of significant infectious diseases in the Asia-Pacific region has been given a boost through a new research collaboration between the National Health and Medical Research Council in Australia and the Agency for Science, Technology and Research in Singapore.

12 Apr 2013

New research shows safety can be improved for people participating in medical experiments

In almost 90 per cent of cases, novel drugs tested on humans by pharmaceutical companies do not work as intended and must be scrapped. Often the drugs do not work, while at worst, test subjects die. New research from the University of Southern Denmark now shows that this number can be reduced.

12 Apr 2013

Newly characterized adenoviruses can cause severe human infections

The ongoing dance between a virus and its host distinctly shapes how the virus evolves. While human adenoviruses typically cause mild infections, recent reports have described newly characterized adenoviruses that can cause severe, sometime fatal, human infections.

12 Apr 2013

Researchers identify defective gene responsible for isolated congenital asplenia

The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections.

12 Apr 2013

Research on soy-based treatment for colorectal cancer presented at AACR annual meeting

Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting.

12 Apr 2013

Brains of different people respond in same way to music, Stanford study says

Do the brains of different people listening to the same piece of music actually respond in the same way? An imaging study by Stanford University School of Medicine scientists says the answer is yes, which may in part explain why music plays such a big role in our social existence.

12 Apr 2013

Illuminating deep mysteries of brain

Researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis developed ultrathin, flexible optoelectronic devices - including LEDs the size of individual neurons - that are lighting the way for neuroscientists in the field of optogenetics and beyond.

12 Apr 2013

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

One of the main obstacles that stands in the way of using human hematopoietic stem cells (hHSCs) to treat a variety of diseases is the difficulty growing them in culture—they quickly die or differentiate into other cell types. A series of experiments that demonstrate the successful use of fat cells as part of a feeder layer to support prolonged growth of hHSCs in culture is reported in an article in BioResearch Open Access, a bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Updated clinical data from phase I study of Ensituximab presented at AACR meeting

Precision Biologics announced today that in conjunction with researchers from Precsion Biologics , Johns Hopkins Medical Center and Duke University Medical Center presented updated clinical data from the phase I study of Ensituximab, a novel therapeutic antibody to treat pancreas and colorectal cancers

11 Apr 2013

Scientists demonstrate feasibility of using already-approved drugs against pathogens

In the most extensive screen of its kind, Texas Biomed scientists in San Antonio have demonstrated the feasibility of repurposing already-approved drugs for use against highly pathogenic bacteria and viruses.

11 Apr 2013

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.

11 Apr 2013

Most people can detect clues to mental illness while playing strategy game

Most people are so attuned to the nuances of social interaction that they can detect clues to mental illness while playing a strategy game with someone they have never met.

11 Apr 2013

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

A dozen Ludwig scientists from around the world presented the latest advancements in basic and clinical cancer research at this week’s American Association for Cancer Research (AACR) Annual Meeting 2013. Progress in immunotherapy and epigenetics led the program with important diagnostic and treatment implications for emerging cancer therapy.

10 Apr 2013

Phase I results show Rogosertib is well tolerated in patients with advanced solid tumors

Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors.

10 Apr 2013

New study shows combination therapy is effective in treating sarcoma tumors

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors.

10 Apr 2013

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli using metagenomics (the direct sequencing of DNA extracted from microbiologically complex samples), according to a study in the April 10 issue of JAMA, a Genomics theme issue.

10 Apr 2013

Tumors with excess copies of MYCN highly sensitive to BET bromodomain inhibitors, researchers find

An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor, a difficult-to-treat, early childhood cancer, is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors, Dana-Farber/Children's Hospital Cancer Center scientists will report at the annual meeting of the American Association for Cancer Research in Washington, April 6-10.

10 Apr 2013

Researchers develop new imaging system for mouse brain studies

Setting a mouse free to roam might alarm most people, but not so for nuclear imaging researchers from the U.S. Department of Energy's Thomas Jefferson National Accelerator Facility, Oak Ridge National Laboratory, Johns Hopkins Medical School and the University of Maryland who have developed a new imaging system for mouse brain studies.

10 Apr 2013

GGA Software Services, Pfizer to present Indigo ELN at 2013 Bio-IT World Conference and Expo

GGA Software Services LLC, a leading provider of outsourced scientific informatics and software services to the life sciences industry, announced today that GGA and Pfizer will present Indigo ELN, the industry's leading open-source chemistry electronic laboratory notebook, at the 2013 Bio-IT World Conference and Expo in Boston, Massachusetts, on Wednesday, April 10, at 12:00 PM.

From Pfizer, Inc. 10 Apr 2013

Laboratory News and Research

Australian, Singapore researchers join hands to combat disease-causing bugs

New research shows safety can be improved for people participating in medical experiments

Newly characterized adenoviruses can cause severe human infections

Researchers identify defective gene responsible for isolated congenital asplenia

Research on soy-based treatment for colorectal cancer presented at AACR annual meeting

Brains of different people respond in same way to music, Stanford study says

Illuminating deep mysteries of brain

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Updated clinical data from phase I study of Ensituximab presented at AACR meeting

Scientists demonstrate feasibility of using already-approved drugs against pathogens

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

Most people can detect clues to mental illness while playing strategy game

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

Phase I results show Rogosertib is well tolerated in patients with advanced solid tumors

New study shows combination therapy is effective in treating sarcoma tumors

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

Tumors with excess copies of MYCN highly sensitive to BET bromodomain inhibitors, researchers find

Researchers develop new imaging system for mouse brain studies

GGA Software Services, Pfizer to present Indigo ELN at 2013 Bio-IT World Conference and Expo

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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