Laboratory News and Research

RSS

High coronary artery calcium together with slow walking speed multiplies risk of mortality

High coronary artery calcium (CAC) together with slow walking speed multiplies the risk of mortality, reveals a new study published in the International Journal of Cardiology. Coronary artery disease is the leading cause of death worldwide and also a common cause of sudden death - heart attack often being the first sign of the disease.

20 Feb 2013

Study may help design better DAA drug cocktails to treat HCV

Hepatitis C virus (HCV) infection affects about 4 million in the United States and is the primary cause of liver cirrhosis and liver cancer. Current therapy against HCV is suboptimal. Daclatasvir, a direct acting antiviral (DAA) agent in development for the treatment of HCV, targets one of the HCV proteins (i.e., NS5A) and causes the fastest viral decline (within 12 hours of treatment) ever seen with anti-HCV drugs.

20 Feb 2013

TIR-199 shows promise in fighting renal cancer

Chemists at the University of California, Riverside have developed a compound that holds much promise in the laboratory in fighting renal (kidney) cancer.

20 Feb 2013

New study reveals how control of brain blood flow develops with age

A new study by Columbia Engineering researchers finds that the infant brain does not control its blood flow in the same way as the adult brain. The paper, which the scientists say could change the way researchers study brain development in infants and children, is published in the February 18 Early Online edition of Proceedings of the National Academy of Sciences (PNAS).

19 Feb 2013

Miniature, ultra-flexible electrodes could open new possibilities for more accurate and local DBS

Some 90,000 patients per year are treated for Parkinson's disease, a number that is expected to rise by 25 percent annually. Deep Brain Stimulation (DBS), which consists of electrically stimulating the central or peripheral nervous system, is currently standard practice for treating Parkinson's, but it can involve long, expensive surgeries with dramatic side effects. Miniature, ultra-flexible electrodes developed in Switzerland, however, could be the answer to more successful treatment for this and a host of other health issues.

19 Feb 2013

Real-time PCR reproducibility improved by handheld electronic pipette

INTEGRA has reported how a leading US clinical diagnostic laboratory has, using a VIAFLO 96 handheld electronic pipette, significantly improved the reproducibility and productivity with which it carries out Real-time PCR assays.

From INTEGRA Biosciences 19 Feb 2013

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin.

18 Feb 2013

New lab at Diamond to help scientists delve into inner workings of pathogens

The UK's national synchrotron facility, Diamond Light Source, is now the first and only place in Europe where pathogens requiring Containment Level 3 - including serious viruses such as those responsible for AIDS, Hepatitis and some types of flu - can be analysed at atomic and molecular level using synchrotron light.

18 Feb 2013

Article details mechanism by which long non-coding RNA-activators promote gene expression

Long segments of RNA- encoded in our DNA but not translated into protein-are key to physically manipulating DNA in order to activate certain genes, say researchers at The Wistar Institute. These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some cancers, in adults.

18 Feb 2013

Positive results from Neurim’s Piromelatine phase II study on insomnia

Neurim Pharmaceuticals announced today positive results from a phase II clinical study evaluating the efficacy and safety of Piromelatine (Neu-P11), a novel investigational multimodal sleep medicine developed for the treatment of patients with primary and co-morbid insomnia.

18 Feb 2013

'Innovations in Imaging' symposium at AAAS to explore leading edge of microscopy

When difficult biological questions are tackled by creative experts in physics, what can result? Images of great beauty, accessible for anyone to appreciate, that also offer rich information on fundamental life processes, and rewarding new paths for analysis and insight.

18 Feb 2013

Researchers discover genetic defect that can halt cell growth

A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.

18 Feb 2013

Researchers explore cellular signals produced by the body in response to traumatic injury

When it comes to healing the terrible wounds of war, success may hinge on the first blood clot - the one that begins forming on the battlefield right after an injury. Researchers exploring the complex stream of cellular signals produced by the body in response to a traumatic injury believe the initial response - formation of a blood clot - may control subsequent healing.

18 Feb 2013

Study paves way for new prosthetics that connect directly to the nervous system

For an amputee, replacing a missing limb with a functional prosthetic can alleviate physical or emotional distress and mean a return of vocational ability or cosmetics. Studies show, however, that up to 50 percent of hand amputees still do not use their prosthesis regularly due to less than ideal functionality, appearance, and controllability. But Silvestro Micera, of the -cole Polytechnique F-d-rale de Lausanne (EPFL) in Switzerland, is paving the way for new, smart prosthetics that connect directly to the nervous system.

18 Feb 2013

Researchers develop nano-machines that recreate principal activities of proteins

Physicists of the University of Vienna together with researchers from the University of Natural Resources and Life Sciences Vienna developed nano-machines which recreate principal activities of proteins.

16 Feb 2013

Parkinson's-related mutations may also affect vision

The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.

16 Feb 2013

Researchers identify mechanism through which mitochondria control breast tumor aggressiveness

Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode-an issue with profound implications for treatment. Now a group from The Scripps Research Institute (TSRI) has identified a mechanism through which mitochondria, the powerhouses of a cell, control tumor aggressiveness.

16 Feb 2013

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Biodiversity in large-scale ecosystems may also provide protection against diseases

The richer the assortment of amphibian species in a pond, the more protection that community of frogs, toads and salamanders has against a parasitic infection that can cause severe deformities, including the growth of extra legs.

16 Feb 2013

Emory receives NINDS grant for biomarker research on Parkinson's

The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a three-year, $900,000 grant to the Center for Biomedical Imaging Statistics at Emory's Rollins School of Public Health.

16 Feb 2013

Laboratory News and Research

High coronary artery calcium together with slow walking speed multiplies risk of mortality

Study may help design better DAA drug cocktails to treat HCV

TIR-199 shows promise in fighting renal cancer

New study reveals how control of brain blood flow develops with age

Miniature, ultra-flexible electrodes could open new possibilities for more accurate and local DBS

Real-time PCR reproducibility improved by handheld electronic pipette

Study describes pharmacological action of TZDs directly on pancreas

New lab at Diamond to help scientists delve into inner workings of pathogens

Article details mechanism by which long non-coding RNA-activators promote gene expression

Positive results from Neurim’s Piromelatine phase II study on insomnia

'Innovations in Imaging' symposium at AAAS to explore leading edge of microscopy

Researchers discover genetic defect that can halt cell growth

Researchers explore cellular signals produced by the body in response to traumatic injury

Study paves way for new prosthetics that connect directly to the nervous system

Researchers develop nano-machines that recreate principal activities of proteins

Parkinson's-related mutations may also affect vision

Researchers identify mechanism through which mitochondria control breast tumor aggressiveness

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Biodiversity in large-scale ecosystems may also provide protection against diseases

Emory receives NINDS grant for biomarker research on Parkinson's

Lab Diagnostics and Automation - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News