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New guidelines to help fast track radiation oncology drug development

Researchers from the translational research program of the National Cancer Institute and the Radiation Therapy Oncology Therapy Group have developed new guidelines to help fast track the clinical development of targeted cancer drugs in combination with radiation therapy.

11 Jan 2013

Johns Hopkins develops PapGene test to diagnose ovarian and endometrial cancers

Using cervical fluid obtained during routine Pap tests, scientists at the Johns Hopkins Kimmel Cancer Center have developed a test to detect ovarian and endometrial cancers. In a pilot study, the "PapGene" test, which relies on genomic sequencing of cancer-specific mutations, accurately detected all 24 (100 percent) endometrial cancers and nine of 22 (41 percent) ovarian cancers. Results of the experiments are published in the Jan. 9 issue of the journal Science Translational Medicine.

11 Jan 2013

TSRI chemists develop new cell-marking method

Chemists at The Scripps Research Institute (TSRI) have found an easier way to perform one of the most fundamental tasks in molecular biology. Their new method allows scientists to add a marker to certain cells, so that these cells may be easily located and/or selected out from a larger cell population.

10 Jan 2013

UCSF Helen Diller Family Comprehensive Cancer Center receives $36M NCI grant

The National Cancer Institute has awarded the UCSF Helen Diller Family Comprehensive Cancer Center a $36 million grant to fund cutting edge research programs and clinical trials over five years.

10 Jan 2013

Loyola uses FilmArray Respiratory Panel to screen infectious diseases

Cold, allergies, the flu or something else? Thanks to advanced technology, physicians at Loyola University Health System receive confirmation of their patient's respiratory illness within one hour. Loyola is one of only two hospitals in lllinois to use the FDA-approved FilmArray Respiratory Panel, which screens for 17 viral and 3 bacterial pathogens in about 60 minutes.

10 Jan 2013

Simple and inexpensive method to cut DNA could transform genetic medicine

A simple, precise and inexpensive method for cutting DNA to insert genes into human cells could transform genetic medicine, making routine what now are expensive, complicated and rare procedures for replacing defective genes in order to fix genetic disease or even cure AIDS.

10 Jan 2013

Competing anesthesiology demands cause missed signals

Competing visual demands and high background noise increase the risk for anesthesiologists missing pulse oximeter pitch changes, shows research.

9 Jan 2013

VolitionRx to commence large internal clinical study for Nucleosomics diagnostic products

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests, announces that it will commence a large internal clinical study for its Nucleosomics diagnostic products this month.

9 Jan 2013

Researchers use electrokinetic patterning to separate particles and microbes by size

Researchers have demonstrated a new technology that combines a laser and electric fields to create tiny centrifuge-like whirlpools to separate particles and microbes by size, a potential lab-on-a-chip system for medicine and research.

9 Jan 2013

Researchers deploy sensitive brain-testing methods on injured high school athletes

The ability to focus and switch tasks readily amid distractions was compromised for up to two months following brain concussions suffered by high school athletes, according to a study at the University of Oregon.

9 Jan 2013

ISCT selects Elsevier to publish Cytotherapy

Elsevier, a world-leading provider of scientific, technical and medical information products and services, is pleased to announce that the International Society for Cellular Therapy (ISCT) has selected Elsevier to publish Cytotherapy: The Journal of Cell Therapy effective January 2013.

8 Jan 2013

Genomic and cellular solutions to be featured by Beckman Coulter Life Sciences at SLAS2013

Bringing together genomic and cellular sample preparation with integrated solutions to highlight their Automation with a Human Touch theme.

From Beckman Coulter Life Sciences - Automation and Genomics 8 Jan 2013

Study highlights role of Protein S in maintenance of healthy retina

Researchers at the Hebrew University of Jerusalem, in collaboration with researchers at the Salk Institute in California, have found for the first time that a specific protein is essential not only for maintaining a healthy retina in the eye, but also may have implications for understanding and possibly treating other conditions in the immune, reproductive, vascular and nervous systems, as well as in various cancers.

7 Jan 2013

Link between Parkinson's and benomyl

For several years, neurologists at UCLA have been building a case that a link exists between pesticides and Parkinson's disease. To date, paraquat, maneb and ziram - common chemicals sprayed in California's Central Valley and elsewhere - have been tied to increases in the disease, not only among farmworkers but in individuals who simply lived or worked near fields and likely inhaled drifting particles.

6 Jan 2013

Scientists report advance toward preventing tooth sensitivity

Taking inspiration from Mother Nature, scientists are reporting an advance toward preventing the tooth sensitivity that affects millions of people around the world. Their report on development of the substance, similar to the adhesive that mussels use to attach to rocks and other surfaces in water, appears in the journal ACS Applied Materials & Interfaces.

4 Jan 2013

ParoChip can allow dentists to quickly detect and analyze periodontitis pathogens

Bleeding gums during tooth brushing or when biting into an apple could be an indication of periodontitis, an inflammatory disease of the tissues that surround and support the teeth. Bacterial plaque attacks the bone, meaning teeth can loosen over time and in the worst case even fall out, as they are left without a solid foundation to hold them in place.

4 Jan 2013

Stanford scientists identify molecular basis for hypertrophic cardiomyopathy

When a young athlete dies unexpectedly on the basketball court or the football field, it's both shocking and tragic. Now Stanford University School of Medicine researchers have, for the first time, identified the molecular basis for a condition called hypertrophic cardiomyopathy that is the most common cause for this type of sudden cardiac death.

4 Jan 2013

Scientists invent scalable method to make polyhydroxylated steroids

Scientists at The Scripps Research Institute (TSRI) have achieved a feat in synthetic chemistry by inventing a scalable method to make complex natural compounds known as "polyhydroxylated steroids." These compounds, used in heart-failure medications and other drugs, have been notoriously problematic to synthesize in the laboratory.

4 Jan 2013

Optofluidics allow for new understanding of resistance to antibiotics

It's often difficult to completely eliminate a bacterial infection with antibiotics; part of the population usually manages to survive. We've known about this phenomenon for quite some time, dating back nearly to the discovery of penicillin. For more than 50 years, scientists have believed that the resistant bacteria were individuals that had stopped growing and dividing.

4 Jan 2013

Scientists discover process by which mda-9/syntenin contributes to melanoma metastasis

After recently announcing success in eliminating melanoma metastasis in laboratory experiments, scientists at Virginia Commonwealth University Massey Cancer Center have made another important discovery in understanding the process by which the gene mda-9/syntenin contributes to metastasis in melanoma (the spread of skin cancer) and possibly a variety of other cancers.

4 Jan 2013