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Renewed classification of primary iron overload syndromes based on Hep25/FP system

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes (PIOSs).

29 Apr 2024

Newly developed organoid model can be used to study thymus function

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus.

29 Apr 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Quest Diagnostics Foundation expands collaboration with Green Bronx Machine to advance health equity

The Quest Diagnostics Foundation today announced an expanded collaboration with Green Bronx Machine (GBM), a transformational educational nonprofit helping students and teachers turn classrooms into agricultural learning experiences.

26 Apr 2024

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder and intellectual disability, as well as a wide range of other moderate-to-profound impairments in mobility, communication, eating and vision.

26 Apr 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Novel SYBR green-based RT-qPCRs developed for lone star virus detection

Announcing a new article publication for Zoonoses journal. Lone Star virus (LSV) is a newly characterized arbovirus with pathogenic potential.

26 Apr 2024

WHO data reveals extensive antibiotic overuse during COVID-19 pandemic

New evidence from the World Health Organization shows the extensive overuse of antibiotics during COVID-19 pandemic worldwide, which may have exacerbated "silent" spread of antimicrobial resistance (AMR).

26 Apr 2024

New study offers promising targets for universal influenza B vaccine

In a milestone study led by the Peter Doherty Institute of Infection and Immunity (Doherty Institute), researchers have identified fragments from influenza B viruses that the immune system consistently recognize, offering promising targets for a universal influenza B vaccine

26 Apr 2024

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

In this interview, Dr. Fu Wei, Director of Quality Management Department at BGI Genomics talks to AZoMedical about achieving and maintaining ISO/IEC 27001 and BS 10012 certifications.

From BGI Genomics 26 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

Bivalent COVID-19 vaccine boosts immunity but needs to be updated

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a Brazilian study reported in the Journal of Medical Virology.

25 Apr 2024

Machine learning system offers new hope for diagnosis of rare genetic disorders

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Brain dynamics and BMI linked to dieting success, study finds

Research reveals that individuals with higher BMI and extensive brain modifications during diet decisions tend to have lower success in diet modification, suggesting the impact of neural plasticity and BMI on diet adherence.

23 Apr 2024

Emulsifiers in processed foods may be linked to increased risk of type 2 diabetes

In Europe and North America, 30 to 60% of dietary energy intake in adults comes from ultra-processed foods.

23 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Study identifies molecular pathway in liver cancer development

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

23 Apr 2024

Laboratory News and Research

Renewed classification of primary iron overload syndromes based on Hep25/FP system

Newly developed organoid model can be used to study thymus function

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Quest Diagnostics Foundation expands collaboration with Green Bronx Machine to advance health equity

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Novel SYBR green-based RT-qPCRs developed for lone star virus detection

WHO data reveals extensive antibiotic overuse during COVID-19 pandemic

New study offers promising targets for universal influenza B vaccine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

Bivalent COVID-19 vaccine boosts immunity but needs to be updated

Machine learning system offers new hope for diagnosis of rare genetic disorders

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Prostaglandin E2: The culprit behind tumor immune evasion

Brain dynamics and BMI linked to dieting success, study finds

Emulsifiers in processed foods may be linked to increased risk of type 2 diabetes

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

Study identifies molecular pathway in liver cancer development

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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