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Penn researchers to develop critical tool for imaging the brains of patients with Parkinson's

Researchers in the Perelman School of Medicine at the University of Pennsylvania will lead a multi-institutional effort in pursuit of developing a critical tool for imaging the brains of patients with Parkinson's and other neurodegenerative diseases.

10 Oct 2019

New review provides knowledge about sex-related differences in Parkinson's disease

There is growing evidence that Parkinson's disease affects women and men differently. In this insightful review, published in the Journal of Parkinson's Disease, scientists present the most recent knowledge about these sex-related differences and highlight the significance of estrogens, which play an important role in the sex differences in PD.

25 Sep 2019

Prilenia's lead compound selected to participate in first-ever ALS platform trial

Prilenia, a newly formed biotech company focused on developing novel treatments for neurodegenerative and neurodevelopmental disorders, announces that Pridopidine, its lead compound, has been selected as the first of three potential new treatments to be included in the launch of the first ever platform trial in amyotrophic lateral sclerosis (ALS).

19 Sep 2019

Johns Hopkins researchers reveal why deep brain stimulation improves Parkinson’s symptoms

In a new study of seven people with Parkinson’s disease, Johns Hopkins Medicine researchers report evidence that deep brain stimulation using electrical impulses jumpstarts the nerve cells that produce the chemical messenger dopamine to reduce tremors and muscle rigidity that are the hallmark of Parkinson’s disease, and increases feelings of well-being.

From Johns Hopkins Medicine 21 Aug 2019

New study analyzes impulsivity in Parkinson's patients treated with Deep Brain Stimulation

Promises of food, sums of money or entertaining pastimes: it does not matter what the temptation is, a new study shows that patients suffering from Parkinson's disease who are treated with Deep Brain Stimulation of the subthalamic nucleus are not more impulsive than others when making decisions about a stimulus that they find particularly appealing.

26 Feb 2019

Experts highlight emerging evidence of impending Parkinson’s disease pandemic

For most of human history Parkinson's disease (PD) has been a rare disorder. However, demography and the by-products of industrialization a now contributing to an impending a Parkinson's pandemic, according to experts writing in a supplement to the Journal of Parkinson's Disease.

29 Jan 2019

Study reveals link between dopamine and reward responses in humans when listening to music

A new study published in Proceedings of the National Academy of Sciences (PNAS), reveals a causal link between dopamine and the reward responses in humans when listening to music.

25 Jan 2019

Study shows how gut bacteria affect the treatment of Parkinson's disease

Patients with Parkinson's disease are treated with levodopa, which is converted into dopamine, a neurotransmitter in the brain. In a study published on 18 January in the journal Nature Communications, scientists from the University of Groningen show that gut bacteria can metabolize levodopa into dopamine.

18 Jan 2019

Combining toxic herbicide with sugar-binding proteins may trigger Parkinsonism

Combining low doses of a toxic herbicide with sugar-binding proteins called lectins may trigger Parkinsonism -- symptoms typical of Parkinson's disease like body tremors and slowing of body motions -- after the toxin travels from the stomach to the brain.

4 Dec 2018

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Cerevance, a clinical-stage drug discovery and development company focused on brain diseases, today announced the start of dosing in a Phase I first-in-human clinical trial of CVN424, an oral compound being developed for symptomatic treatment of Parkinson's disease.

25 Sep 2018

Harmful H. pylori may play a role in Parkinson's disease

While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental causes, prompting enormous interest in identifying environmental risk factors involved.

25 Sep 2018

UA researchers to repurpose ketamine to reduce side effects in Parkinson's patients

The best-known treatment for Parkinson's disease isn't perfect. Named levodopa, the drug can treat the stiffness and slowness of movement associated with the debilitating disease.

19 Jul 2018

Impulse control disorders found to be more common in people taking Parkinson's drugs

Over time, half of the people taking certain drugs for Parkinson's disease may develop impulse control disorders such as compulsive gambling, shopping or eating, according to a study published in the June 20, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Jun 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

New study to test safety, efficacy of MRI-guided focused ultrasound to treat Parkinson's disease

University of Maryland Medicine is leading a phase 3 study to test the safety and efficacy of using MRI-guided focused ultrasound on the brain in order to treat Parkinson's disease.

13 Feb 2018

Scientists test new tactic for controlling motor complications in Parkinson's disease

Standard drug treatment for Parkinson's disease can over time induce motor complications that reduce the effectiveness of restoring mobility.

27 Jan 2018

Existing antidepressant drug could slow progression of Parkinson’s

Michigan State University scientists now have early proof that an antidepressant drug that's been around for more than 50 years could slow the progression of Parkinson's.

6 Sep 2017

Mayo Clinic study: Patients with Parkinson's have higher risk of melanoma and vice versa

People with the movement disorder Parkinson's disease have a much higher risk of the skin cancer melanoma, and vice versa, a Mayo Clinic study finds.

5 Jul 2017

Apomorphine infusion found to be effective treatment for Parkinson’s patients with motor fluctuations

Apomorphine subcutaneous infusion is an effective treatment for Parkinson patients whose motor fluctuations are poorly controlled by conventional therapies.

28 Jun 2017

Study shows evidence that old drug may provide relief for advanced Parkinson's disease patients

New research provides evidence that an old drug may provide relief for people with advanced Parkinson's, according to a study released today that will be presented at the American Academy of Neurology's 69th Annual Meeting in Boston, April 22 to 28, 2017.

20 Apr 2017