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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.
Tree nut consumption associated with lower body weight and lower risk of obesity

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022). [More]
Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Creating bacterial "fight clubs" is an effective way to find new drugs from natural sources. That is the conclusion of a team of Vanderbilt chemists who have been exploring ways to get bacteria to produce biologically active chemicals that they normally hold in reserve. These compounds are called secondary metabolites. [More]
Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

A new study reveals that drinking low-calorie cranberry juice cocktail may help lower the risk of chronic diseases that rank among the leading causes of death worldwide, including heart disease, diabetes and stroke. The finding is welcome news considering the World Health Organization estimates the trio of diseases annually claim 15.6 million lives around the globe. [More]
Researchers discover mechanism that regulates metabolism

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ. [More]
New research sheds light on molecular architecture of receptors linked to many brain diseases

New research sheds light on molecular architecture of receptors linked to many brain diseases

Scientists at The Scripps Research Institute have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's Receptos Inc. and Japanese company Ono Pharmaceutical Co., Ltd., to publish the first 3D structures of a receptor implicated in many diseases of the brain and in normal physiology throughout the body. [More]
TSRI scientists devise powerful set of chemical methods to explore protein biology

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins. [More]
Small intestine causes chronic inflammation in obese patients

Small intestine causes chronic inflammation in obese patients

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region. [More]
WSU research provides new strategies for prevention, treatment of obesity

WSU research provides new strategies for prevention, treatment of obesity

Washington State University scientists have shown that berries, grapes and other fruits convert excess white fat into calorie-burning "beige" fat, providing new strategies for the prevention and treatment of obesity. [More]
Automated droplet-based surface sampling probe analyzes liver biopsy sample in 10 minutes

Automated droplet-based surface sampling probe analyzes liver biopsy sample in 10 minutes

Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers from the Department of Energy's Oak Ridge National Laboratory and Brigham and Women's Hospital/Harvard Medical School. [More]
AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

AstraZeneca today announced a three-year research collaboration with the French National Institute of Health and Medical Research (Inserm) to investigate new therapeutic approaches totype 2 diabetes and Chronic Kidney Disease. [More]
New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

After decades of effort, scientists are finally figuring out how insects develop resistance to environmentally friendly farming practices - such as crop rotation - that are designed to kill them. The researchers say their insights will help develop more sustainable agricultural practices. [More]
Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Amgen today announced that the Company will discuss the data supporting the Repatha (evolocumab) Biologics License Application (BLA) for the treatment of high cholesterol with the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC). [More]
SCIEX and Metabolon® Launch the Lipidyzer™ Platform for Complete Lipid Analysis, from Sample to Biology

SCIEX and Metabolon® Launch the Lipidyzer™ Platform for Complete Lipid Analysis, from Sample to Biology

The new Lipidyzer™ Platform enables you to rapidly and accurately differentiate and quantitate over a thousand lipid species, and translates your data into knowledge with ease and efficiency. [More]
Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Day in and day out, for years on end, millions of people with diabetes prick their fingers to test their blood sugar level. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it. [More]
New clinical data demonstrating treatment options in Lilly's diabetes portfolio to be presented at ADA Scientific Sessions

New clinical data demonstrating treatment options in Lilly's diabetes portfolio to be presented at ADA Scientific Sessions

New clinical data demonstrating the range of treatment options represented in Lilly's diabetes portfolio will be presented in 79 abstracts on June 5-9, at the 75th American Diabetes Association (ADA)® Scientific Sessions in Boston. [More]
Research findings cast new light on biological process that can lead to diabetes

Research findings cast new light on biological process that can lead to diabetes

Oklahoma Medical Research Foundation scientists have pinpointed a cell that begins the process of scarring in fatty tissue. The findings cast new light on a biological process that occurs with obesity and can lead to diabetes. [More]
Changes in cell membrane play pivotal role in how HCV replicates

Changes in cell membrane play pivotal role in how HCV replicates

New research from the University of Southampton has identified how changes in the cell membrane play a pivotal role in how the Hepatitis C virus replicates. [More]
MO BIO announces launch of PowerMag DNA Clean-Up Kit

MO BIO announces launch of PowerMag DNA Clean-Up Kit

MO BIO Laboratories, Inc., the leader in soil, environmental, plant and microbial nucleic acid purification, announces the launch of the PowerMag DNA Clean-Up Kit, for automated, hands-free clean-up of DNA samples that require a secondary purification for removal of PCR inhibitors. This kit features MO BIO's novel ClearMag magnetic bead technology. [More]
Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Researchers at Case Western Reserve University combined finely crafted nanoparticles with one of nature's potent disrupters to prevent the spread of triple-negative breast cancer in mouse models. [More]
Researchers reveal mechanisms involved in development of metabolic complications linked to obesity

Researchers reveal mechanisms involved in development of metabolic complications linked to obesity

Metabolic complications of obesity and overweight, such as type 2 diabetes, are an important challenge to public health. Teams led by Nicolas Venteclef, Inserm Research Fellow (Cordeliers Research Centre, Inserm/Pierre and Marie Curie University Joint Research Unit 1138, Paris, France) and Irina Udalova (Kennedy Institute of Rheumatology, University of Oxford, UK) in collaboration with several teams, have succeeded in elucidating part of the mechanisms involved in the development of these metabolic complications associated with obesity. [More]
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