Liver News and Research

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Cardiohelp assists heart by pumping blood to oxygenator in seriously ill patients

A viral infection was causing life-threatening heart failure in Loyola University Medical Center patient Michelle Rivera.

14 Mar 2013

GABA neuronal deficits in psychiatric disorder can be prevented using N-acetylcysteine: Study

Gamma-aminobutyric acid (GABA) deficits have been implicated in schizophrenia and depression. In schizophrenia, deficits have been particularly well-described for a subtype of GABA neuron, the parvalbumin fast-spiking interneurons.

14 Mar 2013

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α.

14 Mar 2013

Recently employees from SCCA and Fred Hutch receive health care awards

Recently employees from both Fred Hutchinson Cancer Research Center (Fred Hutch) and Seattle Cancer Care Alliance (SCCA) were recognized with industry awards for being leading innovators in health care.

13 Mar 2013

Drugs that combat ageing may be available within five years

Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher.

11 Mar 2013

Acceleron commences ACE-536 phase 2 study in beta-thalassemia

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its novel, investigational protein therapeutic, ACE-536, to treat patients with beta-thalassemia, a genetic hematologic disorder causing chronic and life-threatening anemia and serious complications affecting the spleen, liver and heart.

7 Mar 2013

UK’s health performance declining compared with 14 EU countries over past 20 years

Six decades of universal free health care, the introduction of widespread public health initiatives (eg, tobacco control, cancer screening, and immunisation), and substantial increases in health expenditure have failed to improve the UK’s health outcomes or longevity ranking against the average of 14 other original members of the European Union, Australia, Canada, Norway, and the USA (EU15+) over the past 20 years.

6 Mar 2013

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed without chemotherapy.

6 Mar 2013

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer.

6 Mar 2013

Endocrine Society issues position statement on estradiol measurement

In a Position Statement unveiled today, The Endocrine Society advocates that all methods for measuring estrogens, which play a crucial role in human biology, be made traceable to a common standard.

6 Mar 2013

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Nikolai Begg grew up in a box of LEGO- bricks and hasn't stopped tinkering since. Today he is an accomplished inventor with a portfolio of novel medical devices. Begg is the recipient of the prestigious $30,000 Lemelson-MIT Student Prize for his inventions that are making surgical procedures less invasive.

6 Mar 2013

Deleting Plin2 gene prevents obesity in mice

Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.

6 Mar 2013

Microcystins in drinking water

An interview with Rohan Thakur, discussing the prevalence of microcystins in drinking water, and the use of LC-MS to identify cyanotoxins within water samples.

From Bruker Life Sciences Mass Spectrometry 5 Mar 2013

HIV might promote aging and disease progression in people with HCV, study results suggest

Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus, co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.

5 Mar 2013

Oxidative stress turns protein that protects healthy cells into executioner: Study

Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released today in the Proceedings of the National Academy of Sciences journal.

5 Mar 2013

New tool can accurately forecast malaria epidemics in northwestern India

Sea surface temperatures in the tropical South Atlantic Ocean can be used to accurately forecast, by up to four months, malaria epidemics thousands of miles away in northwestern India, a University of Michigan theoretical ecologist and her colleagues have found.

5 Mar 2013

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Interim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).

5 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Liver News and Research

Cardiohelp assists heart by pumping blood to oxygenator in seriously ill patients

GABA neuronal deficits in psychiatric disorder can be prevented using N-acetylcysteine: Study

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Recently employees from SCCA and Fred Hutch receive health care awards

Drugs that combat ageing may be available within five years

Acceleron commences ACE-536 phase 2 study in beta-thalassemia

UK’s health performance declining compared with 14 EU countries over past 20 years

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Endocrine Society issues position statement on estradiol measurement

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Deleting Plin2 gene prevents obesity in mice

Microcystins in drinking water

HIV might promote aging and disease progression in people with HCV, study results suggest

Oxidative stress turns protein that protects healthy cells into executioner: Study

New tool can accurately forecast malaria epidemics in northwestern India

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Stem cell line could also advance research into liver cancers, cystic fibrosis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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