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FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

The U.S. Food and Drug Administration today expanded the approved use of Zytiga (abiraterone acetate) to treat men with late-stage (metastatic) castration-resistant prostate cancer prior to receiving chemotherapy.

10 Dec 2012

Despite effective anti-viral drugs, majority of HCV patients remain untreated

Just 20 percent of people infected with the hepatitis C virus (HCV) begin the recommended treatment regimen and less than 5 percent go on to successfully overcome the virus, according to a new review in General Hospital Psychiatry.

10 Dec 2012

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

Obese women might be able to eliminate their increased risk for postmenopausal breast cancer by taking measures during perimenopause to prevent weight gain and to therapeutically control the metabolic effects of their obesity, according to the results of a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

10 Dec 2012

Baby boomers with liver cancer drive demand for liver transplantation

New research reveals that the greatest demand for liver transplantation due to hepatitis C (HCV)-related liver disease occurs among Americans born between 1941 and 1960. Findings in the December issue of Liver Transplantation, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD), suggest that continuing increased demand for transplantation is driven by the development of liver cancer in baby boomers with HCV, but that the demand may decrease as patients born in this time period continue to grow older.

7 Dec 2012

LSUHSC to advance research on social, genetic, environmental and behavioral determinants of future obesity

Melinda Sothern, PhD, CEP, Professor and Director of the Behavioral and Community Health Sciences Program at LSU Health Sciences Center New Orleans School of Public Health, has been awarded $675,000 in grant funding to advance her research on the role of social, genetic, environmental and behavioral determinants of future obesity.

7 Dec 2012

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin.

6 Dec 2012

Researchers unlock mechanisms of how the body converts dietary carbohydrates into fat

A gene that helps the body convert that big plate of holiday cookies you just polished off into fat could provide a new target for potential treatments for fatty liver disease, diabetes and obesity.

6 Dec 2012

Tenofovir DF safe and effective in treating adolescents with HBV

A recent clinical trial found that the adult antiviral drug, tenofovir disoproxil fumarate (tenofovir DF), is safe and effective in treating adolescents with hepatitis B virus (HBV). Trial results published in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD), show that tenofovir DF suppressed HBV in 89% of pediatric participants.

6 Dec 2012

Children with HIV more likely to develop atherosclerosis

Children with HIV have a 2.5 fold increased risk of atherosclerosis, according to research presented at EUROECHO and other Imaging Modalities 2012. Antiretroviral treatment, lipid lowering drugs and prevention with healthy lifestyles are needed to prevent early death from cardiovascular disease.

5 Dec 2012

New research finds bisphenol A in fetal liver tissues

New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

4 Dec 2012

Task Force set to back CDC hepatitis C screening

Clinicians should consider screening for hepatitis C virus in all patients born between 1945 and 1965, the US Preventive Services Task Force says in draft guidance.

3 Dec 2012

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

A tiny, translucent zebrafish that glows green when its liver makes glucose has helped an international team of researchers identify a compound that regulates whole-body metabolism and appears to protect obese mice from signs of metabolic disorders.

2 Dec 2012

Men should see a doctor and be proactive about their health, say UAB experts

Experts at the University of Alabama at Birmingham (UAB) say a man's tendency to wait until the onset of sickness to see his doctor is a major detriment to health because key screenings are missed.

1 Dec 2012

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system stands down, leaving a population of sentinel memory cells to rapidly redeploy the immune system in the event of reinfection.

1 Dec 2012

New study on mice could open door to methods of regulating cell proliferation in humans

A newly-engineered strain of mice whose dividing cells express a fluorescent protein could open the door to new methods of regulating cell proliferation in humans.

1 Dec 2012

Diabetes education critical for uncontrolled high blood sugar people with cancer

When people with Type 2 diabetes are diagnosed with cancer -- a disease for which they are at higher risk -- they ignore their diabetes care to focus on cancer treatment, according to new Northwestern Medicine- research. But uncontrolled high blood sugar is more likely to kill them and impairs their immune system's ability to fight cancer.

30 Nov 2012

Engineers develop simple and inexpensive way to create 3-D brain tissues in lab dishes

Borrowing from microfabrication techniques used in the semiconductor industry, MIT and Harvard Medical School (HMS) engineers have developed a simple and inexpensive way to create three-dimensional brain tissues in a lab dish.

30 Nov 2012

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Novartis will highlight more than 140 presentations on key data from its extensive oncology portfolio at the leading year-end scientific meetings devoted to hematology and breast cancer, demonstrating continued innovation in research and development efforts to advance the care of patients with cancer and rare diseases.

30 Nov 2012

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

Varian Medical Systems has received regulatory clearance from the Indian Atomic Energy Regulatory Board for the use of its unique TrueBeam High Intensity Mode for advanced radiosurgical treatments.

29 Nov 2012

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

A three-month-old Winnipeg girl has become the first patient in Canada to receive an experimental and potentially life-saving form of therapy to improve the function of her liver.

29 Nov 2012

Liver News and Research

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

Despite effective anti-viral drugs, majority of HCV patients remain untreated

Perimenopausal lifestyle modifications could reduce risk of breast cancer in obese woman

Baby boomers with liver cancer drive demand for liver transplantation

LSUHSC to advance research on social, genetic, environmental and behavioral determinants of future obesity

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

Researchers unlock mechanisms of how the body converts dietary carbohydrates into fat

Tenofovir DF safe and effective in treating adolescents with HBV

Children with HIV more likely to develop atherosclerosis

New research finds bisphenol A in fetal liver tissues

Task Force set to back CDC hepatitis C screening

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

Men should see a doctor and be proactive about their health, say UAB experts

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

New study on mice could open door to methods of regulating cell proliferation in humans

Diabetes education critical for uncontrolled high blood sugar people with cancer

Engineers develop simple and inexpensive way to create 3-D brain tissues in lab dishes

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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