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Targeted intervention improves safety of MRI scans for children with sickle cell disease

Jude Children's Research Hospital reports success using a targeted educational approach to teach young patients to remain motionless during MRI scans, making the process safer.

1 Sep 2012

Scientists identify specific role of RESA protein in modulating blood circulation

When the parasite responsible for malaria infects human red blood cells, it launches a 48-hour remodeling of the host cells. During the first 24 hours of this cycle, a protein called RESA undertakes the first step of renovation: enhancing the stiffness of the cell membranes.

31 Aug 2012

Stowers investigators define factors that regulate size of cellular fat pools

As the national waistline expands, so do pools of intra-cellular fat known as lipid droplets. Although most of us wish our lipid droplets would vanish, they represent a cellular paradox: on the one hand droplets play beneficial roles by corralling fat into non-toxic organelles. On the other, oversized lipid droplets are associated with obesity and its associated health hazards.

30 Aug 2012

Southampton Traffic Light test could easily diagnose liver fibrosis and cirrhosis

A new 'traffic light' test devised by Dr Nick Sheron and colleagues at University of Southampton and Southampton General Hospital could be used in primary care to diagnose liver fibrosis and cirrhosis in high risk populations more easily than at present.

30 Aug 2012

Israel's Ministry of Health approves Medgenics’ INFRADURE Phase I/II clinical trials for hepatitis C

Medgenics, Inc., the developer of Biopump, a novel technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, today announced that Israel's Ministry of Health (MOH) has approved two Phase I/II clinical trials to assess the safety and efficacy of INFRADURE in patients with hepatitis C.

30 Aug 2012

BMBF awards 16M€ to support German epigenome program initiative

The German Ministry for Research and Education (BMBF) will support the German epigenome program initiative "DEEP" with a budget of 16M€ over 5 years.

29 Aug 2012

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Global platelet reactivity is more effective than responsiveness to clopidogrel in identifying acute coronary syndrome (ACS) patients at high risk of ischemic events, according to research presented at the ESC Congress today. The results from the RECLOSE 2-ACS study were presented by Dr Rossella Marcucci from Italy.

28 Aug 2012

Postoperative complications lead to hospital readmissions among general surgery patients

Postoperative complications are the most significant independent risk factor leading to 30-day hospital readmissions among general surgery patients, according to a new exploratory study published in the September issue of the Journal of the American College of Surgeons.

28 Aug 2012

FDA approves Gilead’s Stribild to treat HIV-1 infection

The U.S. Food and Drug Administration today approved Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate), a new once-a-day combination pill to treat HIV-1 infection in adults who have never been treated for HIV infection.

28 Aug 2012

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Extra pounds-even within the overweight but not obese range-are linked to a higher risk of recurrence of the most common type of breast cancer despite optimal cancer treatment, according to a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

27 Aug 2012

Mexican-Americans with ancestral links have higher insulin resistance levels

Mexican-Americans with an ancestral link to Amerindian tribes were found to have higher insulin resistance levels, which is an indication of several chronic conditions such as type 2 diabetes, according to research by The University of Texas Health Science Center at Houston (UTHealth).

26 Aug 2012

Children with obesity face increased risk for gallstones

Children who are overweight or obese face an increased risk for gallstones, according to a Kaiser Permanente study published in the Journal of Pediatric Gastroenterology & Nutrition.

26 Aug 2012

LXRbeta may play a role in prevention and treatment of Parkinson's

Scientists at the University of Houston (UH) have discovered what may possibly be a key ingredient in the fight against Parkinson's disease.

24 Aug 2012

Nanoparticle may bring great benefits to emergency treatment of brain-injury victims

A nanoparticle developed at Rice University and tested in collaboration with Baylor College of Medicine (BCM) may bring great benefits to the emergency treatment of brain-injury victims, even those with mild injuries.

24 Aug 2012

One blog examines GAVI Alliance's efforts to accelerate introduction of hepatitis B vaccines in developing countries

"I am looking forward to participating in the 2012 World Cancer Leaders' Summit, to be held in Montreal, Canada on August 27," GAVI Alliance Deputy CEO Helen Evans writes in this post in the One Blog.

23 Aug 2012

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Researchers at the Georgia Health Sciences University Cancer Center have identified a gene that disrupts the inflammatory process implicated in liver cancer.

23 Aug 2012

Spicy solution for viral infection

Curcumin, the main compound in the spice turmeric, prevents replication of mosquito-borne Rift Valley Fever virus in infected cells, report researchers.

22 Aug 2012

FDA warns consumers about potential health risks of two natural dietary supplements

The U.S. Food and Drug Administration today issued a new warning to consumers about the potential health risks of two products marketed as natural dietary supplements for treating arthritis, muscle pain, osteoporosis, bone cancer, and other conditions.

22 Aug 2012

Viewpoints: The importance of hepatitis C testing; Medicaid needs to provide coverage for circumcision

I consider myself to be a fortunate person. I have a good education, a great job and excellent health insurance. I am a baby boomer who has aged reasonably well and can look forward to a fairly comfortable retirement. I am also fortunate because I was diagnosed with hepatitis C by a proactive and knowledgeable doctor in the late 1990s and had the opportunity to be treated and cured. The odds are that if I had not been diagnosed and treated, I would be on a liver transplant list right now, have liver cancer or even be dead from this disease.

22 Aug 2012

Bile duct cancer chosen as next indication for PCI Biotech

PCI Biotech (PCIB) the Norwegian biopharmaceutical company, reported today that it has chosen bileduct cancer as the next indication for the use of its PCI (photochemical internalisation) localised cancer therapy. In this indication PCI Biotech’s proprietary photosensitiser Amphinex® will be used in combination with the generic cytotoxic agent gemcitabine. The aim is to start the clinical Proof of Concept study within end of 1H 2013.

21 Aug 2012

Liver News and Research

Targeted intervention improves safety of MRI scans for children with sickle cell disease

Scientists identify specific role of RESA protein in modulating blood circulation

Stowers investigators define factors that regulate size of cellular fat pools

Southampton Traffic Light test could easily diagnose liver fibrosis and cirrhosis

Israel's Ministry of Health approves Medgenics’ INFRADURE Phase I/II clinical trials for hepatitis C

BMBF awards 16M€ to support German epigenome program initiative

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Postoperative complications lead to hospital readmissions among general surgery patients

FDA approves Gilead’s Stribild to treat HIV-1 infection

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Mexican-Americans with ancestral links have higher insulin resistance levels

Children with obesity face increased risk for gallstones

LXRbeta may play a role in prevention and treatment of Parkinson's

Nanoparticle may bring great benefits to emergency treatment of brain-injury victims

One blog examines GAVI Alliance's efforts to accelerate introduction of hepatitis B vaccines in developing countries

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Spicy solution for viral infection

FDA warns consumers about potential health risks of two natural dietary supplements

Viewpoints: The importance of hepatitis C testing; Medicaid needs to provide coverage for circumcision

Bile duct cancer chosen as next indication for PCI Biotech

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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