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New treatment approach improves recurrence-free survival in early breast cancer patients

A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

A study aiming to develop a Lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Lower income and education levels increase risk of alcohol-related medical conditions

Men and women with lower income or education levels are more likely to develop medical conditions related to alcohol abuse compared to similar individuals with a higher socioeconomic status.

19 Mar 2024

Study sheds new light on how CVD is associated with hypertensive disorders of pregnancy

UiB-research sheds light on how CVD is associated with hypertensive disorders of pregnancy - but not for everyone.

19 Mar 2024

Artichoke's health secret, traditional remedy to modern marvel

Study highlights the artichoke's nutritional benefits and its potential to improve cardiovascular health, exhibit neuroprotective effects, and offer antimicrobial properties, emphasizing its value beyond dietary use.

18 Mar 2024

Kallistatin expression increases after weight loss, study reveals

After weight loss, people with overweight and obesity express more of the protein Kallistatin* in subcutaneous white adipose tissue.

18 Mar 2024

Dietary intake post-birth triggers hepatocyte specialization

In mammals, the liver detects the body's energy demand at any given moment and mobilizes nutrient reserves to meet it.

18 Mar 2024

Mouse models shed light on the effects of metformin use during pregnancy on offspring

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently.

18 Mar 2024

Spleen stiffness measurement could revolutionize the diagnosis and management of portal hypertension

Portal hypertension (PHT) is a severe complication of chronic liver disease, like cirrhosis, where increased pressure builds up in the portal vein.

18 Mar 2024

Clinical trial aims to provide a surgical solution for patients with 'inoperable' pancreatic tumors

A clinical trial from Keck Medicine of USC aims to provide a surgical solution for patients with a form of advanced pancreatic cancer previously considered inoperable.

18 Mar 2024

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

If you thought gout was an outdated condition affecting portly, red-faced Victorians, think again.1 in 40 Brits now have this extremely painful disease, making it the UK’s most common form of inflammatory arthritis. Cases among people in their 20s and 30s have increased by 30%, and faster monitoring and treatment is needed, says a leading expert.

18 Mar 2024

Nanoparticles turbocharge turmeric's curcumin for enhanced health benefits

Study explores nanoparticle-enhanced curcumin formulations, promising to significantly boost its health benefits including anticancer, antioxidant, and anti-inflammatory effects by improving bioavailability and bioactivity.

17 Mar 2024

New drug candidate designed at the atomic level could help halt emerging SARS-CoV-2 variants

Although COVID-19 has faded from the headlines, SARS-CoV-2 – the coronavirus behind the pandemic – is still rampantly infecting people around the world.

14 Mar 2024

New analysis sheds light on cancer incidence and mortality trends in the UK

Trends in cancer incidence and deaths in the United Kingdom (UK) among individuals aged between 35 and 69 years.

14 Mar 2024

Study reveals decline in cancer mortality among middle-aged people in the UK

A study by Cancer Research UK has revealed that fewer middle-aged people are dying from cancer in the UK than at any point over the last 25 years.

13 Mar 2024

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

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From ERS Genomics 13 Mar 2024

Limoncella apple polyphenol extract shines in IBD liver damage study

'Limoncella' apple polyphenol extract (LAPE) shows promise in reducing liver and intestinal inflammation in a mouse model of inflammatory bowel disease (IBD), highlighting potential natural treatment pathways

12 Mar 2024

Study links rising metabolic syndrome scores to increased cancer risk

Metabolic syndrome (MetS) score trajectories, especially those increasing over time, are linked to higher risks of various cancer types, with chronic inflammation exacerbating these risks.

12 Mar 2024

Molecular Rosetta stone provides previously unknown insight into gut microbiome communication

Researchers from Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.

12 Mar 2024

Liver News and Research

New treatment approach improves recurrence-free survival in early breast cancer patients

Immune cell protein identified as potential target for rare liver cancer treatment

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

Lower income and education levels increase risk of alcohol-related medical conditions

Study sheds new light on how CVD is associated with hypertensive disorders of pregnancy

Artichoke's health secret, traditional remedy to modern marvel

Kallistatin expression increases after weight loss, study reveals

Dietary intake post-birth triggers hepatocyte specialization

Mouse models shed light on the effects of metformin use during pregnancy on offspring

Spleen stiffness measurement could revolutionize the diagnosis and management of portal hypertension

Clinical trial aims to provide a surgical solution for patients with 'inoperable' pancreatic tumors

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

Nanoparticles turbocharge turmeric's curcumin for enhanced health benefits

New drug candidate designed at the atomic level could help halt emerging SARS-CoV-2 variants

New analysis sheds light on cancer incidence and mortality trends in the UK

Study reveals decline in cancer mortality among middle-aged people in the UK

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

Limoncella apple polyphenol extract shines in IBD liver damage study

Study links rising metabolic syndrome scores to increased cancer risk

Molecular Rosetta stone provides previously unknown insight into gut microbiome communication

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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