Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Researchers develop new method to study liver function and disease

Researchers at Karolinska Institutet in Sweden have developed a method to study liver function and disease without requiring invasive procedures.

1 Feb 2024

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.

31 Jan 2024

Noninvasive diagnostic tool for identification of NASH by visualizing hepatic steatosis and inflammation

Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated fatty liver disease (MAFLD), is spectrum of diseases that ranges from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).

26 Jan 2024

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

A study analyzing UK Biobank data found that individuals who underwent the NHS health evaluation had a lower long-term risk of various diseases and mortality compared to those who did not participate in the assessment.

24 Jan 2024

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

In this interview, we speak with Jack O'Meara, co-founder and CEO of Ochre Bio, a pioneering force in liver disease treatment. O'Meara shares insights into Ochre Bio's innovative RNA therapies, their approach to tackling liver disease, and the company's vision for the future.

24 Jan 2024

Dietary carotenoids may reduce risk of non-alcoholic fatty liver disease, study suggests

Study found no direct link between total dietary vitamin A intake and non-alcoholic fatty liver disease (NAFLD) risk, but observed an inverse correlation between provitamin A carotenoid consumption and NAFLD risk.

23 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).

23 Jan 2024

Study links GLP1 agonists to reduced risk of severe liver disease in diabetic patients

Ozempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes and chronic liver disease, according to a nationwide study from Karolinska Institutet in Sweden published in the journal Gut.

23 Jan 2024

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Coronary heart disease (CHD) and H. Pylori.

23 Jan 2024

Study identifies genetic variants that influence response to preterm birth treatment

A UC San Francisco-led study has for the first time identified genetic variants that predict whether patients will respond to treatment for preterm birth, a condition that affects one in 10 infants born in the United States.

22 Jan 2024

Aerobic exercise could help combat non-alcoholic fatty liver disease

According to a study conducted on animal models and published in the journal Metabolism, aerobic exercise could help fight the non-alcoholic fatty liver disease, the most common liver disease worldwide: it affects nearly 24% of the global population and it usually causes a certain stigma among the affected people.

22 Jan 2024

Exploring the impact of probiotics on preventing weight gain from psychiatric medication

Researchers discuss the effectiveness of probiotics and their use in reducing drug-induced weight loss.

19 Jan 2024

Men with enlarged breast tissue may be at greater risk of early death

Men with enlarged breast tissue, not caused by excess weight—a condition formally known as gynecomastia—may be at heightened risk of an early death before the age of 75, suggests the first study of its kind, published online in the open access journal BMJ Open.

17 Jan 2024

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.

16 Jan 2024

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling.

16 Jan 2024

Exploring the link between pancreatic islet cell loss and age-related health conditions

Researchers from Tokyo Metropolitan University have studied pancreatic islet cell loss in people with no previous pancreatic problems. They identified key trends in the types of cells lost due to islet cell loss in different age groups and sexes, finding that ICL in the elderly population was largely due to insulin-producing beta cell loss.

13 Jan 2024

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

A genome-wide study of 402,398 individuals identifies 369 SNPs associated with insulin resistance, offering insights into metabolic diseases and potential therapeutic targets.

11 Jan 2024

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

New imaging technique could transform diagnosis and treatment of steatotic liver disease

Steatotic liver disease (SLD), previously known as non-alcoholic fatty liver disease, which includes a range of conditions caused by fat build-up in the liver due to abnormal lipid metabolism, affects about 25% of the population worldwide, making it the most common liver disorder.

9 Jan 2024

£30M clinical study will enhance the understanding of NASH cirrhosis

The most extensive clinical study into liver cirrhosis ever conducted worldwide has been announced by Newcastle University, University of Edinburgh and leading research-driven global biopharmaceutical company, Boehringer Ingelheim.

8 Jan 2024

Liver Disease News and Research

Further Reading

Researchers develop new method to study liver function and disease

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

Noninvasive diagnostic tool for identification of NASH by visualizing hepatic steatosis and inflammation

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

Dietary carotenoids may reduce risk of non-alcoholic fatty liver disease, study suggests

3D-printed liver model paves way for new MASH treatments

Study links GLP1 agonists to reduced risk of severe liver disease in diabetic patients

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Study identifies genetic variants that influence response to preterm birth treatment

Aerobic exercise could help combat non-alcoholic fatty liver disease

Exploring the impact of probiotics on preventing weight gain from psychiatric medication

Men with enlarged breast tissue may be at greater risk of early death

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

Exploring the link between pancreatic islet cell loss and age-related health conditions

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

Extended liver preservation technique shows promise for daytime transplants

New imaging technique could transform diagnosis and treatment of steatotic liver disease

£30M clinical study will enhance the understanding of NASH cirrhosis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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