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Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Lactobacillus iners in tumors: Driving chemoradiation resistance via lactate-induced metabolic rewiring

Investigating tumor and gut microbiome traits that impact chemoradiation therapy in patients with cervical cancer.

24 Oct 2023

Kidney transplantation turns back the clock on renal aging

This recent study in the Journal of Internal Medicine reveals that kidney transplantation mitigates the effects of renal aging in chronic kidney disease patients, outperforming dialysis. The research utilized DNA methylation clocks to assess biological age, finding that age acceleration decreased one year post-transplant but remained unchanged with dialysis.

17 Oct 2023

Antiverse and GlobalBio, Inc. extend collaboration to advance antibody cancer therapeutics

Antiverse Ltd (Antiverse) and GlobalBio, Inc. (GlobalBio) today announced they will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy.

From Antiverse 16 Oct 2023

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

In a recent review published in Immunity, researchers reviewed tumor-immunity cycle data.

13 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

What are the pharmacological properties of black goji berries?

The pharmacological effects of the components of Lycium ruthenicum Murray fruits.

29 Sep 2023

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

Mutations on a key SARS-CoV-2 viral protein are linked to extreme immune responses and could offer a novel vaccine target.

27 Sep 2023

How do different polyphenol-rich foods impact chronic diseases?

The potential of phytochemicals in promoting a healthy human diet to combat chronic disease.

27 Sep 2023

AI model accurately forecasts patient outcomes for common lung cancer after surgery

Researchers develop an AI model to accurately predict prognosis for patients with non-small cell lung cancer after surgery. The model, which utilized a range of preoperative and postoperative blood test results, achieved high prediction accuracy, offering a promising approach for personalized treatment plans.

25 Sep 2023

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

A study published in PNAS provides a comprehensive look at the relationship between cell size and count across the human body, drawing from over 1,500 sources and identifying around 400 unique cell types. The research reveals an almost inverse relationship between cell size and count, offering a quantitative framework that could serve as a baseline for understanding cellular composition and function in various applications.

19 Sep 2023

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics.

14 Sep 2023

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Researchers identified diabetic individuals among populations with normal fasting glucose using ML.

12 Sep 2023

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

The hematological parameters and serum biomarkers of inflammation and immunity in patients with atopic dermatitis and psoriasis.

12 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Scientists discover thymic M cells

It came as a surprise to Professor David Lo and his graduate student Diana Del Castillo when they were recently consulted by researchers in Israel for their expertise on specialized cells called Microfold cells, or M cells, which are mostly known for their presence in the intestinal epithelium.

7 Sep 2023

Lymphocyte News and Research

Novel replacement strategy holds promise for the treatment of various genetic disorders

Lactobacillus iners in tumors: Driving chemoradiation resistance via lactate-induced metabolic rewiring

Kidney transplantation turns back the clock on renal aging

Antiverse and GlobalBio, Inc. extend collaboration to advance antibody cancer therapeutics

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Effectiveness of Lactobacillus in treating inflammatory bowel disease

What are the pharmacological properties of black goji berries?

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

How do different polyphenol-rich foods impact chronic diseases?

AI model accurately forecasts patient outcomes for common lung cancer after surgery

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Reviving reservoirs: new findings shake up HIV treatment understanding

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Scientists discover thymic M cells

Immunology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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