MERS CoV News and Research

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In recent history, we have witnessed the emergence of several different life-threatening viruses. In addition to causing serious public health concerns around the globe, they have been responsible for significant human morbidity and mortality. Modern life that entails uncurtailed travel of humans and goods means that initially localized outbreaks may pose a risk of transmission anywhere in the world.

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

In this interview, News-Medical talks to Dr Javier Yugueros-Marcos, Head of the Antimicrobial Resistance and Veterinary Products Department at the World Organisation for Animal Health, about how the world can work together to promote the sustainable and responsible use of antimicrobials.

18 Nov 2022

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).

10 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

In a new study, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity.

31 Oct 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

The swine acute diarrhea syndrome coronavirus promotes autophagy to maintain its replication inside host cells.

26 Oct 2022

A review of emerging pediatric respiratory viruses

Respiratory viruses continue to be a leading cause of childhood morbidity and mortality.

26 Oct 2022

Investigating the evidence of synthetic origins of SARS-CoV-2

Researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated naturally from an animal-to-human spillover or synthetically during coronavirus research experiments.

24 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

In silico studies assess the binding efficacy of phytoconstituents against active sites of SARS-CoV-2.

16 Oct 2022

The impact of humidity levels on viral transmission and viability

A recent PLoS ONE study reviewed the impact of humidity on virus transmission and its viability.

13 Oct 2022

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

The Independent Task Force on COVID-19 and other Pandemics (www.independentcovidtaskforce.org) announced that their report "Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA Viruses" has been published in the Proceedings of the National Academy of Sciences.

10 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

A recent Nature Reviews Immunology study has summarized the efficacy of neutralizing antibodies that target four main regions of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), namely, the receptor-binding domain (RBD) in the S1 subunit, the fusion peptide region in the S2 subunit, the stem helix region, and the N-terminal domain.

2 Oct 2022

MERS CoV News and Research

Further Reading

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

A review of emerging pediatric respiratory viruses

Investigating the evidence of synthetic origins of SARS-CoV-2

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

The impact of humidity levels on viral transmission and viability

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

The involvement of minor intron-containing gene-encoded proteins in viral infections

Spike-specific memory B cells develop resilience to SARS-CoV-2

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

How does SARS-CoV-2 infection and vaccination impact human immune memory?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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