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Brain activation patterns may help identify people at risk for developing bipolar spectrum disorder

Patterns of brain activation during reward anticipation may help identify people most at risk for developing bipolar spectrum disorders, according to a study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.

12 Jun 2019

Study shows how specific mutations in SYNE1 gene may increase bipolar disorder risk

A new study by researchers at The Picower Institute for Learning and Memory at MIT finds that the protein CPG2 is significantly less abundant in the brains of people with bipolar disorder and shows how specific mutations in the SYNE1 gene that encodes the protein undermine its expression and its function in neurons.

9 Jan 2019

Probiotics may offer therapeutic benefits for biopolar patients

A new study has shown that probiotics may serve as a potential therapeutic approach to bipolar disorder and other psychiatric conditions.

13 Dec 2018

FDA clears mobile medical app to help increase retention in recovery program for opioid use disorder

Today, the U.S. Food and Drug Administration cleared a mobile medical application (app) to help increase retention (the amount of time a patient participates) in an outpatient treatment program for individuals with opioid use disorder.

10 Dec 2018

Smokers at greater risk of schizophrenia and psychotic disorders

A team of researchers from University of Queensland have found that tobacco use is associated with an increased risk of psychotic disorders including schizophrenia.

21 Nov 2018

With hospitalization losing favor, judges order outpatient mental health treatment

When mental illness hijacks Margaret Rodgers' mind, she acts out. Rodgers, 35, lives with depression and bipolar disorder. When left unchecked, the conditions drive the Alabama woman to excessive spending, crying and mania.

13 Nov 2018

Multi-national database can help researchers address questions about bipolar disorder throughout adult lifespan

Not much is known about how bipolar disorder (BD) affects people throughout their lives. Do women and men differ in the severity of their symptoms?

23 Oct 2018

Study: Pregnant women with mental health history recognize babies' expressions differently

A pilot study has found that pregnant women who have suffered from depression or bipolar disorder (i.e. both mania and depression) recognize babies' faces and how babies laugh or cry, differently to healthy controls.

8 Oct 2018

Diet and weight may influence response to bipolar disorder treatment, shows study

Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to contribute to general inflammation.

8 Oct 2018

Looking deep inside the brain to accurately diagnose bipolar disorder and depression

New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression.

4 Sep 2018

Study identifies brain-based dimensions of mental health disorders using machine learning

A new study using machine learning has identified brain-based dimensions of mental health disorders, an advance towards much-needed biomarkers to more accurately diagnose and treat patients.

2 Aug 2018

Collaborative care models have proven to improve outcomes and access to mental health care

Mental health has been in the news recently for all the wrong reasons, from unexpected celebrity suicides to a reported increase in depression diagnoses.

23 Jul 2018

Nitrate-cured meats may contribute to mania, study finds

An analysis of more than 1,000 people with and without psychiatric disorders has shown that nitrates-chemicals used to cure meats such as beef jerky, salami, hot dogs and other processed meat snacks-may contribute to mania, an abnormal mood state. Mania is characterized by hyperactivity, euphoria and insomnia.

18 Jul 2018

Study finds elevated risk of congenital defects in lithium-exposed infants

Researchers from the Icahn School of Medicine at Mount Sinai found an elevated risk of major congenital malformations in fetuses after first-trimester exposure to lithium, in the largest study ever to examine the risk of birth defects in lithium-exposed babies.

19 Jun 2018

Lithium treatment associated with lowest risk of rehospitalization for bipolar disorder patients

Individuals with bipolar disorder have the lowest risk of rehospitalization if treated with lithium, according to a study from Karolinska Institutet in Sweden published in JAMA Psychiatry. Long-acting injections of antipsychotics were also effective, reducing the risk of rehospitalization by 30 percent compared with their oral counterparts.

28 Feb 2018

Evidence suggests two patterns of early symptoms precede and predict later BD risk

Two patterns of antecedent or "prodromal" psychiatric symptoms may help to identify young persons at increased risk of developing bipolar disorder (BD), according to a new analysis in the Harvard Review of Psychiatry.

12 Jan 2018

Long-term U-M study yields framework that could be useful for studying bipolar disorder

Nearly 6 million Americans have bipolar disorder, and most have probably wondered why. After more than a decade of studying over 1,100 of them in-depth, a University of Michigan team has an answer – or rather, seven answers.

15 Dec 2017

Molecular method reveals brain circuitry essential for alertness

Using a molecular method likely to become widely adopted by the field, researchers supported by the National Institutes of Health have discovered brain circuitry essential for alertness, or vigilance - and for brain states more generally.

3 Nov 2017

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Sunovion Pharmaceuticals Inc. today announced post-hoc analysis results of a positive Phase 3 placebo-controlled clinical study, as well as interim data from a long-term open-label extension study evaluating Latuda (lurasidone HCI) in children and adolescents (10 to 17 years of age) with major depressive episodes associated with bipolar I disorder (bipolar depression).

28 Oct 2017

Sleep loss can trigger mood episodes in bipolar disorder patients

Sleep loss can trigger relapse, particularly in the form of mania, in people with a diagnosis of bipolar disorder, finds a study by Cardiff University.

19 Oct 2017