Metabolism News and Research RSS Feed - Metabolism News and Research

Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.
Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations. [More]
Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. [More]
Disrupting cancer regulator MYC: an interview with Professor Kim Janda

Disrupting cancer regulator MYC: an interview with Professor Kim Janda

MYC is an oncogenic member of the basic helix-loop-helix-leucine zipper transcription factor family. In its monomeric form, MYC’s tertiary structure is intrinsically disordered and the protein is transcriptionally inactive. [More]
Zebrafish may hold key to unlocking a leading cause of respiratory diseases

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans. [More]
Dairy products contribute to overall metabolic health

Dairy products contribute to overall metabolic health

Dairy is considered part of a healthy diet and dietary guidelines recommend the daily consumption of 2-4 portions of milk-based products such as milk, yogurt, cheese, cream and butter. [More]
Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit a more favorable ratio of estrogen metabolites, which is associated with reduced risk for breast cancer, compared to women with less microbial variation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). [More]
ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, cosmetic and pharmaceutical industries, announced today that it has entered into an ingredient supply agreement with Healthy Directions, a direct-to-consumer nutritional supplement retailer and wholly-owned subsidiary of Helen of Troy Limited. [More]
Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes. [More]
New project aims at delivering innovative test to improve safety of chemical products, drugs

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment. [More]
Study shows importance of adding illness behavior in evaluation of patients with hormone disorders

Study shows importance of adding illness behavior in evaluation of patients with hormone disorders

Nicoletta Sonino and associates, in the current issue of the Journal of Clinical Endocrinology & Metabolism, point to the importance of including illness behavior (the ways in which people experience, perceive, evaluate and respond to their own health status) in the evaluation of patients with hormone disorders. [More]
Agents targeting mitochondrial metabolism can have activity in leukemia

Agents targeting mitochondrial metabolism can have activity in leukemia

Results of a Phase I clinical trial showed that a new drug targeting mitochondrial function in human cancer cells was safe and showed some efficacy. [More]
Short-term use of DPP-4 inhibitors does not increase risk for pancreatic cancer

Short-term use of DPP-4 inhibitors does not increase risk for pancreatic cancer

Researchers at the UNC Gillings School of Global Public Health and the UNC School of Medicine have found that a popular class of diabetes medications called DPP-4 inhibitors does not increase the short-term risk of pancreatic cancer, as was previously reported by other researchers. [More]
Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Fractyl Laboratories Inc. today announced positive clinical data for the first procedural therapy to directly treat the underlying digestive causes of insulin resistance in patients with uncontrolled type 2 diabetes. [More]
Professor receives grant from NIH to test effects of high-intensity functional training

Professor receives grant from NIH to test effects of high-intensity functional training

Katie Heinrich, assistant professor of kinesiology at Kansas State University, has been awarded an investigator-initiated grant from the National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases for more than $2.52 million. [More]
Treatment with SSRIs linked with increased failure risk of osseointegrated implants

Treatment with SSRIs linked with increased failure risk of osseointegrated implants

The International and American Associations for Dental Research (IADR/AADR) have published a paper titled "SSRIs and the Risk of Osseointegrated Implant Failure - A Cohort Study. [More]
New regulatory component in infectious bacterium helps explain ability to survive in human body

New regulatory component in infectious bacterium helps explain ability to survive in human body

The discovery of a new regulatory component in an infectious bacterium could aid efforts to explain its ability to survive in the human body, report microbiologists at The University of Texas Health Science Center at Houston (UTHealth) and University of Maryland, College Park, in the journal Science. [More]
Researchers examine role of blocking vagus nerve in weight loss

Researchers examine role of blocking vagus nerve in weight loss

Among patients with morbid obesity, blocking the vagus nerve, which plays a role with appetite and metabolism, did not meet pre-specified efficacy objectives compared to a control group, although the intervention did result in greater weight loss, according to a study in the September 3 issue of JAMA. [More]
Researchers discover protein that may open door to new method of treating type 2 diabetes

Researchers discover protein that may open door to new method of treating type 2 diabetes

The STK25 protein contributes to cell growth. Researchers at Sahlgrenska Academy have discovered that the protein also affects metabolism, demonstrating that elevated levels accelerate the progress of diabetes in mice. [More]
Coffee increases risk of prediabetes in young adults with hypertension

Coffee increases risk of prediabetes in young adults with hypertension

Coffee increases the risk of prediabetes in young adults with hypertension who are slow caffeine metabolisers, according to results from the HARVEST study presented at ESC Congress today by Dr Lucio Mos from Italy. People who drank more than three cups of coffee per day doubled their risk of prediabetes. [More]
Risk of obesity higher among adults who had been subjected to abuse as children

Risk of obesity higher among adults who had been subjected to abuse as children

Being subjected to abuse during childhood entails a markedly increased risk of developing obesity as an adult. [More]