Metabolism News and Research RSS Feed - Metabolism News and Research

Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.
Pfizer to in-license Absorption Systems' BCRP-MDCK cells

Pfizer to in-license Absorption Systems' BCRP-MDCK cells

Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein). [More]
Medac Pharma's Rasuvo injection gets FDA approval for RA, pJIA and psoriasis

Medac Pharma's Rasuvo injection gets FDA approval for RA, pJIA and psoriasis

Medac Pharma, Inc., a privately held pharmaceutical company focused on the development of new molecules and improving the effectiveness of existing medicines, announced that the U.S. Food and Drug Administration has approved Rasuvo, a subcutaneous injectable methotrexate (MTX) therapy delivered in an auto-injector for rheumatoid arthritis (RA), polyarticular-course juvenile idiopathic arthritis (pJIA) and psoriasis. [More]
Women experiencing stressful events the day before eating high-fat meal can slow body's metabolism

Women experiencing stressful events the day before eating high-fat meal can slow body's metabolism

A new study in women suggests that experiencing one or more stressful events the day before eating a single high-fat meal can slow the body's metabolism, potentially contributing to weight gain. [More]
AZD3965 drug could prove useful in treating small cell lung cancer

AZD3965 drug could prove useful in treating small cell lung cancer

Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer - the most aggressive form of lung cancer. [More]
New drug could prove useful in treating small cell lung cancer

New drug could prove useful in treating small cell lung cancer

Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer - the most aggressive form of lung cancer. [More]
Study reveals effect of 3-n-butylphthalide on chronic ischemic stroke

Study reveals effect of 3-n-butylphthalide on chronic ischemic stroke

The pathogenesis of vascular dementia induced by chronic cerebral ischemia is complex, mainly consisting of energy metabolism disorder, oxidative stress injury, neuronal apoptotic cell death and cholinergic nerve dysfunction. [More]
Research into cell metabolism could open new therapeutic avenues for diabetes, cancer

Research into cell metabolism could open new therapeutic avenues for diabetes, cancer

More scientific research into the metabolism of stromal support cells and immune cells - and the role of the metabolism of these cell types in the development of diseases - could open new therapeutic avenues for diabetes, inflammatory conditions and cancer. That was the conclusion of a review article by scientists from VIB and KU Leuven in the leading journal Nature. [More]
New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

Alzheimer's disease, which is the most common cause of dementia, is fatal and currently, there is no cure. In Alzheimer's disease, brain cells are damaged and destroyed, leading to devastating memory loss. [More]
Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers at the National Institutes of Health have found. [More]
Scientists discover new role for pair of compounds which alter circadian rhythm

Scientists discover new role for pair of compounds which alter circadian rhythm

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex physiological process that responds to a 24-hour cycle of light and dark and is present in most living things. [More]
Scientists discover new compounds that could alter circadian rhythm

Scientists discover new compounds that could alter circadian rhythm

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex physiological process that responds to a 24-hour cycle of light and dark and is present in most living things. [More]
Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells. [More]
High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds. [More]
Transcription factor IRF4 plays key role in brown fat's thermogenic process

Transcription factor IRF4 plays key role in brown fat's thermogenic process

The body contains two types of fat cells, easily distinguished by color: White and brown. While white fat serves to store excess calories until they're needed by the body, brown adipocytes actually burn fat by turning it into heat. [More]
Promising new drug for metabolic syndrome

Promising new drug for metabolic syndrome

University of Utah researchers have discovered that an enzyme involved in intracellular signaling plays a crucial role in developing metabolic syndrome, a finding that has a U of U spinoff company developing a drug to potentially treat the condition. [More]
Researchers discover new way by which metabolism is linked to regulation of DNA

Researchers discover new way by which metabolism is linked to regulation of DNA

A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer. [More]
Nutrition screenings should be mandatory part of comprehensive geriatric analysis

Nutrition screenings should be mandatory part of comprehensive geriatric analysis

As older adults typically have one or more chronic health conditions that can affect dietary intake, malnutrition has been identified as a serious problem in older adults. This has given rise to the recommendation that nutrition screenings be a mandatory part of the comprehensive geriatric analysis (CGA). [More]
Use of stomach feeding tubes in children can lead to persistent gastrocutaneous fistulae

Use of stomach feeding tubes in children can lead to persistent gastrocutaneous fistulae

Pediatric patients with intestinal failure often need gastrostomy tubes, or feeding tubes inserted into an opening created in the stomach, for long-term nutrition. The use of such tubes can lead to persistent gastrocutaneous fistulae, or the failure of the opening to close on its own, resulting in a need for surgical closure. [More]
Study reveals mechanism underlying abnormal fat accumulation in HIV patients

Study reveals mechanism underlying abnormal fat accumulation in HIV patients

Building upon their earlier research on the biology of fat metabolism, Joslin scientists discovered that microRNAs -small RNA molecules that play important roles in regulation in many types of tissue - play a major role in the distribution and determination of fat cells and whole body metabolism. [More]
New gene therapy for Acute Intermittent Porphyria

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle. [More]