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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.
Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight. [More]
TEAAM trial finds that testosterone has no effect on atherosclerosis progression

TEAAM trial finds that testosterone has no effect on atherosclerosis progression

Testosterone sales have grown rapidly over the last decade, but few studies have examined the long-term effects of taking testosterone on cardiovascular health and other important outcomes. This week, investigators from Brigham and Women's Hospital report the results of the Testosterone's Effects on Atherosclerosis Progression in Aging Men (TEAAM) trial in the Journal of the American Medical Association. [More]
Gastric bypass surgery enhances energy expenditure, leads to sustained weight loss

Gastric bypass surgery enhances energy expenditure, leads to sustained weight loss

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight. [More]
Sigma 1 receptor appears to play vital role in supporting the retina

Sigma 1 receptor appears to play vital role in supporting the retina

A receptor that is already a target for treating neurodegenerative disease also appears to play a key role in supporting the retina, scientists report. [More]
Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Turing Pharmaceuticals AG today announced that it has acquired the exclusive rights to market Daraprim (pyrimethamine) in the U.S. from Impax Laboratories, Inc. The acquisition by Turing is part of a strategic effort focused on treatments for toxoplasmosis and other serious infectious diseases. The company also announced plans to invest in the development of new drug candidates for toxoplasmosis. [More]
Lexicon Pharmaceuticals' revenues decrease to $0.4 million in second quarter 2015

Lexicon Pharmaceuticals' revenues decrease to $0.4 million in second quarter 2015

Lexicon Pharmaceuticals, Inc., today reported financial results for the second quarter ended June 30, 2015 and provided an overview of key milestones for the company's lead drug candidates. [More]
Scientists publish new important clues about marrow fat

Scientists publish new important clues about marrow fat

While most of us worry about the fat cells building up on the fleshy parts of our bodies, scientists have started to pay serious attention to another kind of fat cell deep inside our bones, in what's called the marrow. [More]
BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

Researchers at Beth Israel Deaconess Medical Center have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases. [More]
TSRI study shows antioxidants slow aging process, reduce risk of infection

TSRI study shows antioxidants slow aging process, reduce risk of infection

Scientists from the Florida campus of The Scripps Research Institute have shown how aging cripples the production of new immune cells, decreasing the immune system’s response to vaccines and putting the elderly at risk of infection. [More]
Inflammation from diets deficient in nutrients contribute to weight despite intake of macronutrients

Inflammation from diets deficient in nutrients contribute to weight despite intake of macronutrients

If you are watching what you eat, working out, and still not seeing improvements in your cholesterol, blood pressure, blood sugar, etc., here's some hope. A new report appearing in the August 2015 issue of The FASEB Journal suggests that inflammation induced by deficiencies in vitamins and minerals might be the culprit. [More]
Metformin drug has impact on blood fat levels

Metformin drug has impact on blood fat levels

Besides affecting the blood sugar levels, the substance Metformin, also has an impact on blood fat levels. This was elucidated by an interdisciplinary team of the German Center for Diabetes Research headed by Dr. Rui Wang-Sattler of the Helmholtz Zentrum München. Especially the harmful LDL cholesterol can be reduced. [More]
New research shows gastric bypass surgery lowers alcohol tolerance in women

New research shows gastric bypass surgery lowers alcohol tolerance in women

Women who have gastric bypass surgery to lose weight should keep a close eye on their alcohol consumption, according to new research at Washington University School of Medicine in St. Louis. [More]
Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

In a collaborative study between Sanford Burnham Prebys Medical Discovery Institute and the Argonne National Laboratory, scientists have used a highly specialized X-ray crystallography technique to solve the protein structure of hypoxia-inducible factors (HIFs), important regulators of a tumor's response to low oxygen (hyopoxia). [More]
Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Joslin scientists have advanced understanding of how the cellular repair process is impaired in type 1 diabetes, which can cause cell death and lead to complications. The findings appear in the August issue of Cell Metabolism. [More]
Study finds evidence that gut microbes affect circadian rhythms, metabolism in mice

Study finds evidence that gut microbes affect circadian rhythms, metabolism in mice

A study including researchers from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago found evidence that gut microbes affect circadian rhythms and metabolism in mice. [More]
AMRI’s total revenue increases $89.5 million to 31% in second quarter 2015

AMRI’s total revenue increases $89.5 million to 31% in second quarter 2015

AMRI today reported financial and operating results for the second quarter ended June 30, 2015. "We are very pleased to present another strong financial quarter, with all our divisions achieving excellent results," said William S. Marth, AMRI's president and chief executive officer. "Notably, recent acquisitions, combined with the cost reduction initiatives and efficiency efforts we've made to date, are contributing to continued strong contract margin performance. [More]
Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015. [More]
Study reveals new gene that plays crucial role in ASD

Study reveals new gene that plays crucial role in ASD

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS/Aix-Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP-HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under-expression may induce certain autistic traits. [More]
NYSCF scientists design new robotic platform to automate generation of patient-specific stem cells

NYSCF scientists design new robotic platform to automate generation of patient-specific stem cells

Scientists at The New York Stem Cell Foundation Research Institute successfully designed a revolutionary, high-throughput, robotic platform that automates and standardizes the process of transforming patient samples into stem cells. [More]
Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Starvation early in life can alter an organism for generations to come, according to a new study in roundworms. The effects are what Duke University biologist Ryan Baugh terms a "bet-hedging strategy." [More]
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