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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.
Unknown exposure to second-hand smoke linked to increased mortality in non-smokers

Unknown exposure to second-hand smoke linked to increased mortality in non-smokers

A new biomarker has identified known and unknown exposure to second-hand smoke and confirmed a strong association to increased mortality in non-smokers, according to a new study from the Icahn School of Medicine at Mount Sinai. [More]
Maternal serum levels of nicotinamide linked to child’s risk of atopic eczema

Maternal serum levels of nicotinamide linked to child’s risk of atopic eczema

Infants whose mothers had a higher level of a particular type of vitamin B during pregnancy have a lower risk of eczema at age 12 months, new Southampton research has shown. [More]
Oral antidiabetic drug modulates the body's nitrogen and urea metabolism

Oral antidiabetic drug modulates the body's nitrogen and urea metabolism

The most frequently prescribed oral antidiabetic drug metformin significantly affects metabolic pathways. [More]
Researchers describe how genetic mutations cause unnamed neurological disorder

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder. [More]
ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Scientists from Tohoku University's Tohoku Medical Megabank Organization have published research about genetic diversity and metabolome in Scientific Reports. [More]
Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell." [More]
CFS possesses objectively identifiable chemical signature in men and women, study reveals

CFS possesses objectively identifiable chemical signature in men and women, study reveals

Dauer is the German word for persistence or long-lived. It is a type of stasis in the development in some invertebrates that is prompted by harsh environmental conditions. The findings are published online in the August 29 issue of PNAS. [More]
Research finds differences in breast milk of women who gave birth to pre-term infants

Research finds differences in breast milk of women who gave birth to pre-term infants

About 7 percent of all Danish children are born prematurely. This is of significant im-portance not only to the child's development, but it also affects the mother's body that - unexpectedly - has to produce the necessary nutrition for the newborn baby. [More]
Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis. [More]
Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients. [More]
Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

A drink developed for soldiers to generate energy from ketones rather than carbs or fat allowed highly trained cyclists to add up to 400 meters of distance to their workouts, a UK-led study reports July 27 in Cell Metabolism. [More]
New study reports gymnastics equipment contains toxic flame-retardants linked to ADHD, cancer risks

New study reports gymnastics equipment contains toxic flame-retardants linked to ADHD, cancer risks

As the summer Olympics get underway, a new study co-authored by Boston University School of Public Health researchers reports that popular gymnastics training equipment contains mixtures of flame-retardant chemicals that have been linked to increased risks of ADHD, cancer and brain development delays. [More]
Retained metabolites may contribute to impaired cognitive function in kidney failure patients

Retained metabolites may contribute to impaired cognitive function in kidney failure patients

Retention of certain metabolites in the blood may contribute to cognitive impairment in patients with kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. [More]
New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

In biomedical research, working with tissue samples is indispensable because it permits insights into the biological reality of patients, for example, in addition to those gained from Petri dishes and computer simulations. [More]
Rare antibiotic compound detected in fungi for first time

Rare antibiotic compound detected in fungi for first time

Besides mushrooms such as truffles or morels, also many yeast and mould fungi, as well as other filamentous fungi belong to the Ascomycota phylum. They produce metabolic products which can act as natural antibiotics to combat bacteria and other pathogens. Penicillin, one of the oldest antibiotic agents, is probably the best known example. [More]
Food chemists find garlic aroma in breast milk of women who have consumed garlic

Food chemists find garlic aroma in breast milk of women who have consumed garlic

Food chemists at Friedrich-Alexander-Universität Erlangen-Nürnberg have found that garlic aroma is evident in the breast milk of women who have consumed garlic. [More]
Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies. [More]
Urolithin A found in pomegranates may improve muscle strength and endurance during aging

Urolithin A found in pomegranates may improve muscle strength and endurance during aging

Amazentis SA, an innovative life sciences company applying scientific breakthroughs in nutrition to manage health conditions linked to aging, announced today a collaborative publication in Nature Medicine with the École Polytechnique Fédérale de Lausanne, demonstrating that the Company's lead product candidate, urolithin A, improves mitochondrial and muscle function, resulting in enhanced muscle strength and endurance during aging. [More]
Researchers develop computer model for speed analysis of TB's complex life-cycle

Researchers develop computer model for speed analysis of TB's complex life-cycle

Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, is a serious global health problem accounting for 1.3 million worldwide deaths annually. [More]
Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

All life on the planet relies, in one way or another, on a process called carbon fixation: the ability of plants, algae and certain bacteria to "pump" carbon dioxide (CO2) from the environment, add solar or other energy and turn it into the sugars that are the required starting point needed for life processes. [More]
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