Metabolite News and Research

RSS

Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

New sustainable diagnostic approach offers precision cancer testing with minimal environmental impact

Accurate and cost-effective cancer detection.

24 Apr 2024

New tool hunts for Alzheimer's clues in gut microbiome

Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

23 Apr 2024

Bidirectional Mendelian randomization uncovers link between plasma metabolites and heart attack risk

Myocardial infarction, more commonly known as a heart attack, is a leading cause of death worldwide. Biomarkers called plasma metabolites may play a key role in the physiological pathways involved in myocardial infarctions.

17 Apr 2024

Is psilocybin safe for treating depression and anxiety?

A study in JAMA Network Open examined the acute adverse effects of therapeutic doses of psilocybin for treating depression and anxiety, focusing on its safety profile by assessing the occurrence of immediate side effects like headache, nausea, and elevated blood pressure among others.

12 Apr 2024

Linking lifestyle to longevity: How diet and hypertension sway risks for heart disease and cancer

Study reviews epidemiological evidence linking modifiable risk factors like diet and hypertension to both cardiovascular disease (CVD) and cancer, suggesting a shared pathophysiology and potential strategies for simultaneous prevention and management.

11 Apr 2024

Study reveals key gut microbiome differences in prediabetic patients

Study explores the differences in gut microbiome composition between prediabetic patients and healthy individuals, revealing significant variations that correlate with altered metabolic functions and potential diabetes progression.

11 Apr 2024

High blood levels of TMAO predicts chronic kidney disease risk in future

New findings from Cleveland Clinic and Tufts University researchers show high blood levels of TMAO (trimethylamine N-oxide) predicts future risk of developing chronic kidney disease over time.

9 Apr 2024

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Wastewater study sheds light on tracking cannabis use challenges

Researchers explore wastewater-based surveillance (WBS) as a tool to monitor cannabis use, identifying analytical challenges and the need for more precise methodologies.

3 Apr 2024

Infant gut microbiomes exhibit circadian rhythms independent of external cues

Infant gut microbiomes oscillate with a circadian rhythm, even when they are cultivated outside of the body.

2 Apr 2024

Household chemicals endanger brain's myelin-forming cells

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential neurodevelopmental risks such as ADHD and autism, by employing an innovative high-throughput screening approach on mouse and human stem cell-derived models.

26 Mar 2024