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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.
Research report on global market for drug discovery technologies

Research report on global market for drug discovery technologies

Reportlinker.com announces that a new market research report is available in its catalogue: Drug Discovery Technologies - A Global Market Overview [More]
BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

Austrian BIOCRATES Life Sciences AG, internationally renowned developer and marketer of innovative targeted metabolomics solutions, further expands its range of metabolomics-based kits with the addition of its assay for the determination of endogenous bile acids, allowing a panel of up to 19 analytes to be simultaneously quantitated from a single 10 µL sample of human or mouse plasma. [More]
Postdischarge intervention helps smokers quit smoking

Postdischarge intervention helps smokers quit smoking

Among hospitalized adult smokers who wanted to quit, a postdischarge intervention that included automated telephone calls and free medication resulted in higher sustained smoking cessation rates at six months than standard postdischarge advice to use smoking cessation medication and counseling, according to a study in the August 20 issue of JAMA. [More]
Imaging system rapidly detects molecular marker in brain gliomas, enables removal of tumor

Imaging system rapidly detects molecular marker in brain gliomas, enables removal of tumor

During tumor surgery, surgeons work to remove tumor tissue without damaging surrounding healthy tissue. [More]
Exposure of pregnant women and fetuses to antibacterial compounds leads to health risk

Exposure of pregnant women and fetuses to antibacterial compounds leads to health risk

As the Food and Drug Administration (FDA) mulls over whether to rein in the use of common antibacterial compounds that are causing growing concern among environmental health experts, scientists are reporting today that many pregnant women and their fetuses are being exposed to these substances. [More]
Bacteria that aid in digestion help keep intestinal lining intact

Bacteria that aid in digestion help keep intestinal lining intact

Scientists at Albert Einstein College of Medicine of Yeshiva University have found that bacteria that aid in digestion help keep the intestinal lining intact. [More]
ChromaDex to provide Murdoch Childrens Research Institute with NR ingredient for research use

ChromaDex to provide Murdoch Childrens Research Institute with NR ingredient for research use

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, animal health, cosmetic and pharmaceutical industries, announced today it has entered into a material transfer agreement (MTA) with Murdoch Childrens Research Institute, the preeminent child health research institute in Australia. [More]
Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke. [More]
Right kind of fat keeps the heart healthy

Right kind of fat keeps the heart healthy

Too much dietary fat is bad for the heart, but the right kind of fat keeps the heart healthy, according to a paper published in The Journal of Experimental Medicine. [More]
New study finds highest rates of decline in prescription drug misuse nationwide

New study finds highest rates of decline in prescription drug misuse nationwide

Five states that have implemented multi-faceted prescription drug abuse prevention programs in recent years showed the highest rate of decline in prescription drug misuse rates nationwide, according to a new study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services. [More]
Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemopre­vention is to arrest or reverse the progression of pre­malignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells. [More]
Study: Stress can disrupt process of fat tissue development

Study: Stress can disrupt process of fat tissue development

Using experimental models, researchers at Boston University School of Medicine (BUSM) showed that adenosine, a metabolite released when the body is under stress or during an inflammatory response, stops the process of adipogenesis, when adipose (fat) stem cells differentiate into adult fat cells. [More]
Mass spectrometry-based tool successfully used in brain cancer surgery

Mass spectrometry-based tool successfully used in brain cancer surgery

A tool to help brain surgeons test and more precisely remove cancerous tissue was successfully used during surgery, according to a Purdue University and Brigham and Women's Hospital study. [More]

Backpack-sized device can perform highly accurate and sensitive cocaine testing in 15 minutes

Testing for cocaine and other drugs usually involves two steps: a quick on-site prescreen, and then a more accurate confirmatory test at a distant laboratory. [More]
Adding MM-398 to standard treatment improves survival in metastatic pancreatic cancer patients

Adding MM-398 to standard treatment improves survival in metastatic pancreatic cancer patients

Adding the novel MM-398 to standard treatment for metastatic pancreatic cancer patients who have already received gemcitabine improves survival, researchers said at the ESMO 16th World Congress on Gastrointestinal Cancer in Barcelona. [More]
Small molecule in pregnant women's urine apparently blocks cancer growth

Small molecule in pregnant women's urine apparently blocks cancer growth

University of Montreal scientists have identified a small molecule found in pregnant women's urine that apparently blocks the growth of several types of cancers, including AIDS-related Kaposi's sarcoma, which currently has no cure. [More]
Debiopharm launches Phase 1 study of anti-infective agent Debio 1450

Debiopharm launches Phase 1 study of anti-infective agent Debio 1450

Debiopharm Group, a Swiss-based global biopharmaceutical company developing prescription drugs that target unmet medical needs as well as companion diagnostics, today announced the launch of a Phase 1 dose-escalation study of Debio 1450 (previously known as AFN-1720), a highly potent anti-infective agent that is selectively active against a large number of Staphylococcus species, including all known resistant strains such as methicillin-resistant S. aureus (MRSA) and vancomycin-intermediate S. aureus (VISA). [More]

Double Emulsion System released by Dolomite

Microfluidic products expert Dolomite have released their Double Emulsion System for creating micron sized emulsion droplets that contain still smaller droplets inside. It enables unrivalled reproducibility and selectivity of droplet size of both outer and inner phases with either oil-in-water-in-oil or water-in-oil-in-water droplets. The Double Emulsion System is highly beneficial to applications in the food industry, in pharmaceuticals and cosmetics that use double emulsions as delivery vehicles or encapsulation solutions for various active ingredients, or more generally in paints and coatings. [More]
Progress in constructing protein nanomachines

Progress in constructing protein nanomachines

A route for constructing protein nanomachines engineered for specific applications may be closer to reality. [More]
A novel strategy to uncover new antibiotics

A novel strategy to uncover new antibiotics

Resistance to antibiotics has been steadily rising, posing a threat to public health. Now, a method from Mohammad Seyedsayamdost, an assistant professor of chemistry at Princeton University, may open the door to the discovery of a host of potential drug candidates. [More]