Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

MD Anderson researchers named Fellows to new AACR academy

Five researchers and leaders from The University of Texas MD Anderson Cancer Center have been named Fellows to a new academy launched by the world's oldest and largest organization dedicated to cancer research, the American Association for Cancer Research.

29 Mar 2013

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute.

28 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

Researchers discover protein that play role in spread of pancreatic cancer

Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the body.

26 Mar 2013

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

New imaging agent detects, maps cancers that have reached lymph nodes

Researchers at the University of California, San Diego School of Medicine have shown that a new imaging dye, designed and developed at UC San Diego Moores Cancer Center, is an effective agent in detecting and mapping cancers that have reached the lymph nodes.

21 Mar 2013

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Researchers at the University of Maryland School of Medicine have identified a peptide, or protein, derived from Pacific cod that may inhibit prostate cancer and possibly other cancers from spreading, according to preclinical research published online in the Proceedings of the National Academy of Sciences.

20 Mar 2013

Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Tivozanib is an oral, once-daily, investigational tyrosine kinase inhibitor, or TKI, that is being investigated for use in patients with advanced renal cell carcinoma (RCC), or kidney cancer.

19 Mar 2013

Small kidney tumours have aggressive potential and should be treated, study says

Small kidney tumours have an aggressive potential and should be treated, according to a the results of a large multicentre study presented at the 28th Annual EAU Congress in Milan.

18 Mar 2013

Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

While many researchers believe that the Hedgehog (Hh) signaling pathway, which transmits information to embryonic cells for proper development and is important for regeneration, may actually regulate cell-cell adhesion and segregation - there isn't any evidence.

16 Mar 2013

Subcutaneous administration of Herceptin preferred by HER2-positive breast cancer patients over IV

Results from the PrefHer (Patient Preference for Subcutaneous (SC) versus Intravenous (IV) Herceptin) trial show that 92% of early HER2-positive breast cancer patients favoured quicker SC administration of Herceptin compared to the standard IV infusion.1 Presented at the St. Gallen Breast Cancer Conference in Switzerland.

15 Mar 2013

IU researchers awarded $3.2 million grant to develop new treatments for pancreatic cancer

Two Indiana University researchers have been awarded a multi-year, $3.2 million grant to develop and improve therapies for pancreatic cancer, the fourth leading cause of cancer death in the United States.

14 Mar 2013

UNM scientists identify chemical compound that appears to control cell metastases

It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of metastatic cancer cells.

14 Mar 2013

Researchers discover new mechanism that allows collective cell migration

Researchers at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC) have discovered a new mechanism that allows some cells in our body to move together, in some ways like the tortoise formation used by Roman soldiers depicted in the Asterix series.

12 Mar 2013

Lower back pain and spinal cancer: an interview with Dr Nicholas Henschke, University of Heidelberg

While lower back pain is a common condition around the world, in only a very small proportion of people – less than 5% - will this be caused by a serious problem such as fracture, infection, or tumour.

7 Mar 2013

Prostate tissue androgen content predicts ADT outcome

Determining the androgen content in prostate tissue could predict patients’ responses to androgen deprivation therapy and the risk for castration-resistant prostate cancer, show study findings.

6 Mar 2013

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer.

6 Mar 2013

tRNA synthetases play unexpected and critical role in cancer metastasis

Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.D., University of Vermont professor of pharmacology, and Christopher Francklyn, Ph.D., UVM professor of biochemistry.

5 Mar 2013

Children with low-risk retinoblastoma do not need postoperative chemotherapy

New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether. Avoiding chemotherapy spares patients from treatment side effects and long-term health risks, such as cardiovascular disease and development of a second cancer.

5 Mar 2013

Metastasis News and Research

Further Reading

MD Anderson researchers named Fellows to new AACR academy

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

Two studies shed light on molecular biology of three blood disorders

Researchers discover protein that play role in spread of pancreatic cancer

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

Protein with key job in muscle function moonlights in nucleus to help regulate genes

New imaging agent detects, maps cancers that have reached lymph nodes

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Small kidney tumours have aggressive potential and should be treated, study says

Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

Subcutaneous administration of Herceptin preferred by HER2-positive breast cancer patients over IV

IU researchers awarded $3.2 million grant to develop new treatments for pancreatic cancer

UNM scientists identify chemical compound that appears to control cell metastases

Researchers discover new mechanism that allows collective cell migration

Lower back pain and spinal cancer: an interview with Dr Nicholas Henschke, University of Heidelberg

Prostate tissue androgen content predicts ADT outcome

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

tRNA synthetases play unexpected and critical role in cancer metastasis

Children with low-risk retinoblastoma do not need postoperative chemotherapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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