Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Avastin plus Folfox4 chemotherapy significantly extends survival in second-line metastatic colorectal cancer

Genentech and Roche today announced that a randomized Phase III study of Avastin™ (bevacizumab) plus the FOLFOX4 chemotherapy regimen (oxaliplatin/5-FU/leucovorin), compared to FOLFOX4 alone, in second-line metastatic colorectal cancer patients achieved its primary endpoint of improving overall survival.

29 Nov 2004

New software for the investigation of cancer

NorayBio, a bioinformatics company located at the Bizkaia Technological Park (Basque Country) and specialising in developing software for the biosciences, has launched a new software for cancer research on to the market - BITIA, primarily aimed at research centres and cancer wards in hospitals.

16 Nov 2004

Celebrex may one day be used to prevent and even treat breast tumors

The anti-inflammatory drug Celebrex, or celecoxib, reduces tumor mass by encouraging cell death and discouraging both cell proliferation and the sprouting of new blood vessels that feed growing tumors, according to a study reported in the November issue of Molecular Cancer Research.

5 Nov 2004

Potential new treatment strategy against metastatic cancer cells

A team of scientists at The Scripps Research Institute has identified a potential treatment strategy against metastatic cancer cells that has never been tried before.

25 Oct 2004

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

Each year approximately 50,000 women under the age of 40 are diagnosed with breast cancer. Treatments vary but most involve the administration of chemotherapeutic agents or radiation which can disrupt ovarian function or damage a patient’s eggs.

18 Oct 2004

Obese women with early breast cancer at greater risk of death

Women who are obese when they are diagnosed with early stage breast cancer are at greater risk of dying of their disease than women of normal weight

6 Oct 2004

Discovery of key molecular step which allows cancer cells to move to different parts of the body

Researchers at The University of Texas M. D. Anderson Cancer Center have figured out a key molecular step by which a cancer cell can unhook itself from the mesh weave of other cancer cells in a tumor, and move away to a different part of the body - the process, known as metastasis, that makes cancer so dangerous.

27 Sep 2004

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center now have evidence that receptors found on tumors that were believed to function only on the surface of cells can actually switch on genes inside a cell's nucleus, thus promoting cancer development in two distinct ways.

21 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Researchers have discovered a possible way to distinguish lethal from localized prostate cancers

If future studies show their test -- measuring the level of activity of a signaling pathway called Hedgehog -- can predict which prostate cancers will spread, the results could revolutionize decision making processes for prostate cancer patients, the researchers say.

13 Sep 2004

Mammography screening reduces risk of distant tumor recurrence

Women who have breast cancer detected by mammography screening have a reduced risk of distant tumor recurrence than women with breast cancer detected outside of screening, according to a study in the September 1 issue of JAMA.

1 Sep 2004

Scientists have uncovered a key driver behind the progression of prostate cancer

Scientists at Fred Hutchinson Cancer Research Center have uncovered a key driver behind the progression of prostate cancer, a discovery that the researchers believe could spawn new treatments to prevent the cancer's spread and extend survival.

23 Aug 2004

Powerful new cancer-fighting property of Herceptin

For many patients with advanced breast cancer, the cancer drug Herceptin (trastuzumab) has offered new hope when traditional cancer drugs failed to work, shrinking tumors and sending some patients into remission.

23 Aug 2004

Receptor for estrogen in ovarian cells has been shown to suppress tumor growth

An important receptor for estrogen in ovarian cells has been shown to suppress tumor growth, according to a new study published in the August 15 issue of the journal Cancer Research.

15 Aug 2004

Genentech announces FDA approval of Avastin manufacturing

Genentech has announced that the U.S. Food and Drug Administration approved the supplemental Biologics License Application (sBLA) for the manufacturing of Avastin™ (bevacizumab) bulk drug substance at the company's facility in Vacaville, California.

11 Aug 2004

Molecular pathway in the brain may explain why some patients suffering from inflammatory diseases develop depression

Feeling sick can be "all in the head" for people with inflammatory disorders or for those receiving immunotherapy, say Robert Dantzer and Keith Kelley, professors in the department of animal sciences at the University of Illinois at Urbana-Champaign.

29 Jul 2004

Discovery challenges current thinking about how a cancer develops and spreads

When a physician discovers cancer in a patient, the first thing the doctor wants to know is whether that cancer has spread, or "metastasized."

20 Jul 2004

Targeted therapeutics capable of preventing or limiting the metastasis of skin cancer

An international team of scientists has identified an important molecular link involved in the spread – or metastasis – of melanoma to other organs such as the lungs.

15 Jul 2004

Important milestone for any cancer therapy that will be useful for treating patients

Mayo Clinic researchers have manipulated a human antibody to induce an anti-tumor response in living mice that consistently curbs - and often cures - malignant melanoma, one of the most lethal forms of skin cancer and the most common cancer of young adults.