Metastasis News and Research RSS Feed - Metastasis News and Research

Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases
New risk classification system proposed for prostate cancer

New risk classification system proposed for prostate cancer

US researchers have put forward a risk stratification system for patients with intermediate-risk prostate cancer undergoing dose-escalated external-beam radiation therapy. [More]
Student researchers get new view of the dynamics of cancer cells as they metastasize

Student researchers get new view of the dynamics of cancer cells as they metastasize

A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of Prof. Robert Ros, and the lead author of a paper reporting on the topic. [More]
Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Cancer cells that can break out of a tumor and invade other organs are more aggressive and nimble than nonmalignant cells, according to a new multi-institutional nationwide study. [More]
Study confirms that mesenchymal stem cells may help treat cancer

Study confirms that mesenchymal stem cells may help treat cancer

Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central's open access journal Stem Cell Research & Therapy. [More]
Biological imaging technologies create a new way to learn about cells

Biological imaging technologies create a new way to learn about cells

Researchers have married two biological imaging technologies, creating a new way to learn how good cells go bad. "Let's say you have a large population of cells," said Corey Neu, an assistant professor in Purdue University's Weldon School of Biomedical Engineering. [More]
Surgery extends life for metastatic colorectal cancer patients

Surgery extends life for metastatic colorectal cancer patients

Individuals with colorectal cancer that has metastasized to the liver or lung live longer after curative surgery plus chemotherapy than their counterparts who receive palliative chemotherapy alone, report researchers. [More]
Epstein–Barr virus linked to improved gastric cancer survival

Epstein–Barr virus linked to improved gastric cancer survival

Research shows that Epstein–Barr virus positivity in gastric tumor cells is associated with improved prognosis. [More]

Mechanism of tumor suppressor p53 inactivation described

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond repair. Not surprisingly, p53’s critical function is disrupted in most cancers. [More]

New risk classification system proposed for prostate cancer

US researchers have put forward a risk stratification system for patients with intermediate-risk prostate cancer undergoing dose-escalated external-beam radiation therapy. [More]
Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. [More]

XBiotech announces enrollment of first patient in Xilonix Phase III trial for treatment of cachexia

XBiotech announced today enrollment of the first patient into its Phase III trial of Xilonix. The Pivotal study is designed to improve health and survival of late stage colorectal cancer patients with associated cachexia. [More]
CNIO researcher-led consortium to receive MRA grant to advance research in melanoma

CNIO researcher-led consortium to receive MRA grant to advance research in melanoma

A consortium led by the Spanish National Cancer Research Centre's researcher Mar-a S. Soengas −Programme Director of the Centre-s Molecular Pathology Programme and Leader of the CNIO Melanoma Group− has been selected to receive funding from the Melanoma Research Alliance, the most important private international melanoma research foundation, in order to advance research in melanoma; this type of skin tumour represents one of oncology's biggest challenges due to its high incidence and malignancy. [More]
Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices that strike a balance between selflessness and selfishness. [More]
Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the main cause of cancer-related deaths. [More]
Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs. [More]
Study provides medical chemists with tools to design safer drugs, predict their side effects

Study provides medical chemists with tools to design safer drugs, predict their side effects

Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs. [More]

Photoacoustic imaging helps preserve healthy nodes in patients with metastasized cancer

If a tumour has spread through the lymph nodes, the decision is often taken to exercise caution and remove extra tissue, to prevent it from spreading further. This often involves the removal of healthy lymph nodes. [More]
Shc plays key role in activating and controlling Erk

Shc plays key role in activating and controlling Erk

A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports this week in Nature Structural Molecular Biology. [More]
PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

Pharmaco-Kinesis Corporation, developer of a pre-commercialized smart implantable pump for localized cancer-fighting drug delivery, today announced its first commercialized offering, the first-generation Nano-Impedance Biosensor. [More]

Research: Transcription factors regulating oxygen levels in blood play a role in melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma. [More]