Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Antibodies validated for use with Bio-Rad’s Celselect Slides™ enumeration stain kits to enable immunostaining of captured circulating tumor cells in liquid biopsy samples.

From Bio-Rad Laboratories 26 Mar 2024

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

A team of the University of Barcelona and the Biomedical Research Institute of Barcelona (IRB Barcelona) has designed a new bioinformatics tool to identify the chromosomal alterations that are characteristic of cancer cells.

21 Mar 2024

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

A study aiming to develop a Lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

Synthetic mucins shed light on cancer biology and tumor formation

During cold and flu season, excess mucus is a common, unpleasant symptom of illness, but the slippery substance is essential to human health.

18 Mar 2024

Machine learning classifier reduces the time to identify personalized tumor reactive T cell receptors

Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

15 Mar 2024

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

Age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center.

12 Mar 2024

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State.

11 Mar 2024

AI method can predict brain metastasis in lung cancer patients

Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient.

11 Mar 2024

Study evaluates diet, exercise patterns among colorectal cancer patients with overweight/obesity

Obesity is a chronic metabolic disease associated with the development of several other diseases, including cancer. The present study aims to evaluate the eating habits, physical activity, and clinical profiles of colorectal cancer (CRC) patients with overweight/obesity.

7 Mar 2024

European initiative aims to advance the understanding of RNA communication

RNA, which stands for ribonucleic acid has become a mainstream word in society due to the COVID-19 RNA vaccine - yet the value of this biomolecule to society could extend to numerous sectors including food security and personalized medicine.

5 Mar 2024

Scientists take the first step toward early diagnosis of metastasis formation

Metastases are largely responsible for the death rate of patients with solid cancers; the prognosis of cancer patients reduces significantly if metastases are diagnosed.

4 Mar 2024

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers.

29 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Metastasis News and Research

Further Reading

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

Study uncovers how APOBEC enzymes drive cancer mutations

Synthetic mucins shed light on cancer biology and tumor formation

Machine learning classifier reduces the time to identify personalized tumor reactive T cell receptors

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

AI method can predict brain metastasis in lung cancer patients

Study evaluates diet, exercise patterns among colorectal cancer patients with overweight/obesity

European initiative aims to advance the understanding of RNA communication

Scientists take the first step toward early diagnosis of metastasis formation

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Flavonol-rich diet linked to lower mortality and disease risk, study shows

Glitazone drug use by diabetic patients associated with lower risk of primary and secondary brain cancer

Understanding how stress accelerates cancer spread

Natural killer cells lead the charge in cancer treatment innovation

Can dietary patterns impact stomach cancer risk?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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