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NIH-sponsored Phase 1 clinical trial evaluates novel investigational West Nile virus vaccine

A novel investigational West Nile virus vaccine discovered and developed by scientists at the Oregon National Primate Research Center at Oregon Health & Science University is being evaluated in an NIH-sponsored Phase 1, first-in-human, clinical trial at Duke University. Although several early-stage West Nile virus vaccine clinical trials have been completed to date, no human vaccine has been approved for commercial use.

7 May 2015

BD reports revenues of $2.051 billion for second fiscal quarter 2015

BD (Becton, Dickinson and Company), a leading global medical technology company, today reported quarterly revenues of $2.051 billion for the second fiscal quarter ended March 31, 2015, representing a decrease of 1.0 percent from the prior-year period, or an increase of 4.9 percent on a foreign currency-neutral basis.

From BD (Becton, Dickinson and Company) 7 May 2015

Adelaide researchers identify target for developing new antibiotics against disease-causing bacteria

University of Adelaide researchers have discovered a target for the development of completely new antibiotics against disease-causing bacteria.

7 May 2015

Fecal transplantation cures C. diff infection, eliminates multi-drug resistant pathogens

A fecal microbiota transplant (FMT) not only cured a case of Clostridium difficile (C. diff) infection in a 66 year old man; it eliminated populations of multi-drug resistant organisms both in the patient's gastrointestinal tract, and several other body sites.

7 May 2015

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

The ulcer-causing bacterium Helicobacter pylori can directly interact with stomach stem cells, causing the cells to divide more rapidly, according to a new study by researchers at the Stanford University School of Medicine.

7 May 2015

Researchers examine alternative antimicrobials to lower bacterial contamination in fresh produce

Nearly half of foodborne illnesses in the U.S. from 1998 through 2008 have been attributed to contaminated fresh produce. Prevention and control of bacterial contamination on fresh produce is critical to ensure food safety. The current strategy remains industrial washing of the product in water containing chlorine. However, due to sanitizer ineffectiveness there is an urgent need to identify alternative antimicrobials, particularly those of natural origin, for the produce industry.

30 Apr 2015

Novel approaches to fight infections presented at the Pipeline Corner at ECCMID

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) announced breaking developments in the global fight against infections – with new mechanisms and approaches presented by smaller companies in a dedicated pipeline session at the annual congress (ECCMID) in Copenhagen.

30 Apr 2015

Researchers describe critical connection associated with environmental cause of silicosis, lung cancer

Researchers at the University of Louisville have detailed a critical connection associated with a major environmental cause of silicosis and a form of lung cancer. Their study is reported in today's Nature Communications.

29 Apr 2015

Ebola - the implications of a worldwide epidemic

Ebola – from a small village in Guinea, the deadly virus took hold of West Africa in 2014, and to date has taken the lives of over 10,000 people. The virus threatens to destabilize world health efforts and has induced global fear, with citizens from far away nations concerned about the “what ifs?” of Ebola landing on their doorsteps...

29 Apr 2015

TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

TAXIS Pharmaceuticals, a drug-discovery company focused on developing a new class of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections, today announced the presentation of data demonstrating the promise of its lead clinical candidate, TXA709, in combating antibiotic resistance.

27 Apr 2015

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, announced that preclinical data from its novel SYN-005 program for the treatment of Pertussis were presented in two posters at ECCMID 2015 (European Congress of Clinical Microbiology and Infectious Diseases), on April 25, 2015, in Copenhagen, Denmark.

27 Apr 2015

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

A new study led by University of Toronto researcher Dr. David Lam has discovered the trigger behind the most severe forms of cancer pain. Released in top journal Pain this month, the study points to TMPRSS2 as the culprit: a gene that is also responsible for some of the most aggressive forms of androgen-fuelled cancers.

24 Apr 2015

Leading scientists warn of 'Antibiotic Armageddon' in Britain and Europe by 2025

A group of leading scientists has warned that Britain and Europe collectively could face more than a million deaths in an impending "Antibiotic Armageddon” unless more is spent on developing new cures, rapid diagnostics and preventative measures to combat the spread of drug resistant diseases.

24 Apr 2015

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Debiopharm International SA, part of Debiopharm Group, a Swiss-based global biopharmaceutical company, today announced the start of a clinical phase II study to evaluate Debio 1450 for the treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) due to Staphylococci, including all resistant Staphylococcus strains, tested so far.

23 Apr 2015

Metanome changes name to Diversigen

Metanome, Inc., an industry leader in comprehensive microbiome services, today announced the company has changed its name to Diversigen, Inc. The name was changed to reflect Diversigen's positioning as the single commercial source for the myriad of services and expertise customers need to capitalize on the diverse opportunities of the microbiome.

23 Apr 2015

Rising shortages of key antibiotics raise serious concerns about effects on patient care

Shortages of key antibiotics, including gold-standard therapies and drugs used to treat highly resistant infections, are on the rise, according to a new study of shortages from 2001 to 2013 published in Clinical Infectious Diseases and available online. The trends raise serious concerns about the effects on patient care, particularly for infections without effective alternative treatment options.

23 Apr 2015

New UM SOM study uncovers never-before-seen illness transmitted by ticks

Tick-borne diseases are a major public health problem around the world. Ticks carry and transmit a variety of microbes that cause disease. These illnesses, which include Lyme disease, Rocky Mountain spotted fever, and Tularemia, can cause a variety of symptoms, often serious and sometimes deadly.

23 Apr 2015

New patent-pending detection method identifies bacteria contaminating oysters

In a major breakthrough in shellfish management and disease prevention, researchers at the University of New Hampshire have discovered a new method to detect a bacterium that has contaminated New England oyster beds and sickened consumers who ate the contaminated shellfish.

23 Apr 2015

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Adseverin, a protein found in the body, has been identified as the key driver behind the bone loss associated with the world's most common inflammatory disease: gum disease, or periodontitis.

23 Apr 2015

French clinicians diagnose first case of rabies since 2003

A team of French clinicians has diagnosed the first case of rabies in that country since 2003. Only 20 cases of human rabies had been diagnosed in France between 1970 and 2003. Moreover, the patient was unaware of having been bitten.

22 Apr 2015

Microbiology News and Research

NIH-sponsored Phase 1 clinical trial evaluates novel investigational West Nile virus vaccine

BD reports revenues of $2.051 billion for second fiscal quarter 2015

Adelaide researchers identify target for developing new antibiotics against disease-causing bacteria

Fecal transplantation cures C. diff infection, eliminates multi-drug resistant pathogens

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

Researchers examine alternative antimicrobials to lower bacterial contamination in fresh produce

Novel approaches to fight infections presented at the Pipeline Corner at ECCMID

Researchers describe critical connection associated with environmental cause of silicosis, lung cancer

Ebola - the implications of a worldwide epidemic

TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

Leading scientists warn of 'Antibiotic Armageddon' in Britain and Europe by 2025

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Metanome changes name to Diversigen

Rising shortages of key antibiotics raise serious concerns about effects on patient care

New UM SOM study uncovers never-before-seen illness transmitted by ticks

New patent-pending detection method identifies bacteria contaminating oysters

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

French clinicians diagnose first case of rabies since 2003

Microbiology eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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