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New study sheds light on mechanism that affects AID enzyme

A new study by immunology researchers at the IRCM led by Javier M. Di Noia, PhD, sheds light on a mechanism affecting AID, a crucial enzyme for the immune response. The scientific breakthrough, published in the latest issue of The Journal of Experimental Medicine, could eventually improve the way we treat the common flu, as well as lymphoma and leukemia.

21 Apr 2015

Two existing drugs may reverse damage caused by multiple sclerosis

A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.

21 Apr 2015

Study reveals new target for research into liver disease

In a recent study, Virginia Commonwealth University School of Medicine researchers predicted which cirrhosis patients would suffer inflammations and require hospitalization by analyzing their saliva, revealing a new target for research into a disease that accounts for more than 30,000 deaths in the United States each year.

20 Apr 2015

Maple syrup makes disease-causing bacteria more susceptible to antibiotics, study shows

A concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics, according to laboratory experiments by researchers at McGill University.

17 Apr 2015

Researchers reveal the precise mechanism used by bacteria to target invading viruses

One of the immune system's most critical challenges is to differentiate between itself and foreign invaders -- and the number of recognized autoimmune diseases, in which the body attacks itself, is on the rise.

17 Apr 2015

Inflammation plays causal role in neurologic changes associated with Lyme disease

About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. New research indicates that inflammation plays a causal role in the array of neurologic changes associated with Lyme disease, according to a study published in The American Journal of Pathology.

17 Apr 2015

James Allison to be honored with 2015 Pezcoller Foundation-AACR International Award for Cancer Research

The 2015 Pezcoller Foundation-American Association for Cancer Research (AACR) International Award for Cancer Research will be presented to James P. Allison, PhD, at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

17 Apr 2015

Researchers examine how probiotics can help improve health, prevent disease

In recent years, research into the benefits of gut bacteria has exploded. Scientists across the globe are examining how these microbes can help improve health and prevent disease.

16 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

The Centers for Disease Control and Prevention (CDC), in partnership with the Sierra Leone College of Medicine and Allied Health Sciences and the Sierra Leone Ministry of Health and Sanitation, is now enrolling and vaccinating volunteers for the Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE).

15 Apr 2015

Vanderbilt researcher awarded $950,000 grant to explore inheritable bacterial infections

Seth Bordenstein, associate professor of biological sciences and pathology, microbiology and immunology, has been awarded a $950,000 grant from the National Science Foundation for research into the regulation of bacterial infections that are passed from mother to offspring.

12 Apr 2015

New automated tool rapidly delivers large particles into mammalian cells

A new device developed by UCLA engineers and doctors eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.

10 Apr 2015

Challenges involved in tracing the source of Legionnaires’ disease outbreak

Genetic research helps to explain why tracing the source of an outbreak of Legionnaires' disease that claimed four lives has proven to be more complicated than scientists hoped.

10 Apr 2015

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

Cardio3 BioSciences, a leader in engineered cell therapies with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a significant patent application covering T-Cell receptor-deficient T-Cells which are engineered to express a chimeric antigen receptor.

9 Apr 2015

Study may point to immediate cause of CF exacerbations

In the genetic disorder cystic fibrosis (CF), the most severe symptoms are recurring episodes of lung inflammation and bacterial infection (known as "exacerbations") that happen from one to three times a year and cause ever-increasing amounts of lung damage through the course of a CF patient's life.

9 Apr 2015

New study describes economic consequences of using T2Candida Panel for detection of candidemia

A new study describes a model that estimates the economic consequences of using the T2Candida Panel (a novel diagnostic product that provides Candida detection) as an adjunct to the current blood culture-based diagnostic strategy in a high-risk hospital patient cohort.

9 Apr 2015

UTMB scientists develop quick-acting vaccine that is effective against Ebola strain

An interdisciplinary team from The University of Texas Medical Branch at Galveston and Profectus BioSciences, Inc. has developed a quick-acting vaccine that is both safe and effective with a single dose against the Ebola strain that killed thousands of people in West Africa last year.

8 Apr 2015

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs.

8 Apr 2015

CXCR3 molecule is key mediator of melanoma metastasis, shows research

In a unique partnership demonstrating excellence in "team science," Dartmouth investigators from Norris Cotton Cancer Center identified a role for the molecule CXCR3 (widely known to regulate the migration of immune cells) as a key mediator of melanoma metastasis.

7 Apr 2015

Common cancers deform mitochondria to create conducive environment for tumor growth

In a breakthrough in the understanding of how cancer does its deadly work, researchers at the University of Virginia School of Medicine have shown that many cancers - including nearly all pancreatic cancers - enslave and deform mitochondria, the powerhouses of cells, to create an environment more conducive to tumor growth.

7 Apr 2015

Microbiology News and Research

New study sheds light on mechanism that affects AID enzyme

Two existing drugs may reverse damage caused by multiple sclerosis

Study reveals new target for research into liver disease

Maple syrup makes disease-causing bacteria more susceptible to antibiotics, study shows

Researchers reveal the precise mechanism used by bacteria to target invading viruses

Inflammation plays causal role in neurologic changes associated with Lyme disease

James Allison to be honored with 2015 Pezcoller Foundation-AACR International Award for Cancer Research

Researchers examine how probiotics can help improve health, prevent disease

Genetically modified Salmonella can help kill cancer cells

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

Vanderbilt researcher awarded $950,000 grant to explore inheritable bacterial infections

New automated tool rapidly delivers large particles into mammalian cells

Challenges involved in tracing the source of Legionnaires’ disease outbreak

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

Study may point to immediate cause of CF exacerbations

New study describes economic consequences of using T2Candida Panel for detection of candidemia

UTMB scientists develop quick-acting vaccine that is effective against Ebola strain

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

CXCR3 molecule is key mediator of melanoma metastasis, shows research

Common cancers deform mitochondria to create conducive environment for tumor growth

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Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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