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Scientists identify defects in colossal heart protein which leads to stroke, heart failure

Scientists identify defects in colossal heart protein which leads to stroke, heart failure

The landmark discovery of a tiny defect in a vital heart protein has for the first time enabled heart specialists to accurately pinpoint a therapeutic target for future efforts in developing a drug-based cure for cardiovascular diseases. [More]
Common antimicrobial in household items causes liver fibrosis, cancer in mice

Common antimicrobial in household items causes liver fibrosis, cancer in mice

Triclosan is an antimicrobial commonly found in soaps, shampoos, toothpastes and many other household items. Despite its widespread use, researchers at University of California, San Diego School of Medicine report potentially serious consequences of long-term exposure to the chemical. [More]
Study finds link between body weight change and hip fracture risk among Singapore Chinese

Study finds link between body weight change and hip fracture risk among Singapore Chinese

While a low body mass index (BMI) of less than 20 kg/m2 has been shown to be an independent risk factor for hip fractures, far less is known about the relationship of body weight changes on hip fracture risk. [More]
Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

A study led by Massachusetts General Hospital (MGH) investigators has identified what appears to be a molecular switch controlling inflammatory processes involved in conditions ranging from muscle atrophy to Alzheimer's disease. [More]
Studies evaluate traditional management of heart attack patients after discharge from hospital

Studies evaluate traditional management of heart attack patients after discharge from hospital

Beta-blockers have been a cornerstone in the treatment of heart attack survivors for more than a quarter of a century. However, many of the data predate contemporary medical therapy such as reperfusion, statins, and antiplatelet agents, and recent data have called the role of beta-blockers into question. [More]
Researchers create microtube platform to analyze neuron growth

Researchers create microtube platform to analyze neuron growth

Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury. [More]
New findings could help develop therapeutic options for glycogen storage disease

New findings could help develop therapeutic options for glycogen storage disease

Glycogen storage disorders, which affect the body's ability to process sugar and store energy, are rare metabolic conditions that frequently manifest in the first years of life. Often accompanied by liver and muscle disease, this inability to process and store glucose can have many different causes, and can be difficult to diagnose. [More]
FDA approves ImThera Medical's investigational device exemption for pivotal study

FDA approves ImThera Medical's investigational device exemption for pivotal study

ImThera Medical, Inc., a privately held global medical device company, today announced that the U.S. Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) for its THN3 Clinical Study. [More]
Worst effects of reperfusion injury after heart attack may be prevented with iodide

Worst effects of reperfusion injury after heart attack may be prevented with iodide

Blocked arteries are typically the trigger, stopping the flow of blood and starving the heart muscle of oxygen. But when the blockage is removed and the blood comes rushing back, it wreaks havoc of its own. The result is called reperfusion injury, a life-threatening flood of inflammation and cellular destruction that has stumped scientists for 40 years. [More]
Chikungunya outbreak in Caribbean, Central and South America continues to spread

Chikungunya outbreak in Caribbean, Central and South America continues to spread

Fall in the United States means residents in most of the country will see fewer mosquitoes and less risk of the diseases they spread. However, the chikungunya outbreak in Caribbean and Central and South American countries continues to spread with no sign of slowing down. Experts at the Centers for Disease Control and Prevention are warning that the painful mosquito-borne disease will likely continue to infect travelers to the region during the rest of this year and beyond. [More]
Johns Hopkins researchers capture images of protein complex that keeps hearts beating

Johns Hopkins researchers capture images of protein complex that keeps hearts beating

For years, a multidisciplinary team of Johns Hopkins researchers has tracked an elusive creature, a complex of proteins thought to be at fault in some cases of sudden cardiac death. As they report Nov. 5 in the online edition of Nature Communications, they have finally captured images of the complex. [More]
Eight organizations to receive IHF grants to improve care for military veterans

Eight organizations to receive IHF grants to improve care for military veterans

Infinite Hero Foundation today announced that eight organizations will receive charitable grants to fund therapies that address the most critical mental and physical challenges facing returning military veterans and their families. [More]
Latest findings on Chiari malformation to be presented at Akron conference

Latest findings on Chiari malformation to be presented at Akron conference

Researchers from around the country will gather Friday and Saturday at The University of Akron to share the latest findings on Chiari malformation, a neurological disorder at the bottom of the brain that causes at least 300,000 Americans to endure head and neck pain, loss of fine motor control and many other symptoms. [More]
Cardio3 BioSciences announces acquisition of CorQuest Medical

Cardio3 BioSciences announces acquisition of CorQuest Medical

Cardio3 BioSciences, a leader in the discovery and development of regenerative, protective and reconstructive therapies, announces today that it has acquired U.S.-based CorQuest Medical Inc. CorQuest Medical specializes in the development of innovative devices and technologies for cardiac surgery. [More]
Study suggests possible link between body fat and risk of immunotherapy toxicity

Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. [More]
Type 2 diabetes and cardiovascular disease share common risk factors

Type 2 diabetes and cardiovascular disease share common risk factors

Type 2 diabetes (T2D) and cardiovascular disease (CVD) appear to have a lot in common. They share risk factors such as obesity and they often occur together. If they also share the same genetic underpinings, then doctors could devise a way to treat them together too. [More]
Cellular-level changes in nerve structure and function may contribute to migraine headaches

Cellular-level changes in nerve structure and function may contribute to migraine headaches

A new study shows cellular-level changes in nerve structure and function that may contribute to the development of migraine headaches, reports the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). [More]
Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Rigel Pharmaceuticals reports net loss of $20.9 million for third quarter of 2014

Rigel Pharmaceuticals, Inc. today reported financial results for the third quarter and nine months ended September 30, 2014. [More]
CytRx provides overview of clinical development programs, reports 2014 Q3 financial results

CytRx provides overview of clinical development programs, reports 2014 Q3 financial results

CytRx Corporation (CYTR), a biopharmaceutical research and development company specializing in oncology, today reported financial results for the three months ended September 30, 2014, and also provided an overview of recent accomplishments by and upcoming milestones for its clinical development programs. [More]
UC Davis researchers link increased body fat and lethal drug reactions in mice

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy. [More]