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Researchers identify new myosin kinase that could optimize heart contractions

Researchers identify new myosin kinase that could optimize heart contractions

The heart is the only muscle that contracts and relaxes continuously over a lifetime to pump oxygen-rich blood to the body's organs. Researchers at UT Southwestern Medical Center now have identified a previously unrecognized enzyme that could optimize contraction and lead to new strategies to treat heart failure. [More]
Regular exercise can help retain, repair and regenerate damaged muscle in older adults

Regular exercise can help retain, repair and regenerate damaged muscle in older adults

Exercise may have some surprising benefits for seniors who experience rapid muscle loss and muscle injury and loss as they age. Researchers at McMaster University have found that physical activity can help retain, even repair and regenerate damaged muscle in the elderly. [More]
Regular exercise may help improve muscle repair response in older adults

Regular exercise may help improve muscle repair response in older adults

Here's another reason why you should hit the gym regularly as you grow older: A new report appearing online in The FASEB Journal shows that regular exercise plays a critical role in helping muscles repair themselves as quickly as possible after injury. [More]
IOF urges clinicians in Asia to prepare for escalating crisis of osteoporosis among elderly people

IOF urges clinicians in Asia to prepare for escalating crisis of osteoporosis among elderly people

The International Osteoporosis Foundation is calling on doctors in the Asia-Pacific region to prepare for an immense rise in the number of elderly people suffering broken bones as a result of osteoporosis. [More]
ERCC2 validated as chemotherapy response biomarker in bladder cancer

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Somatic mutations in the helicase-encoding ERCC2 gene are associated with response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive urothelial bladder carcinoma. [More]
Obese teenagers more likely to develop heart failure in early middle age

Obese teenagers more likely to develop heart failure in early middle age

Research that followed more than 1.6 million Swedish men from adolescence onwards between 1968 and 2005 has shown that those who were overweight as teenagers were more likely to develop heart failure in early middle age. [More]
Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions. [More]
Dirty working environment can impact cognitive function of employees

Dirty working environment can impact cognitive function of employees

A new study by a Florida State University researcher shows that both a lack of stimulation in the workplace and a dirty working environment can have a long-term cognitive effect on employees. [More]
Mother's obesity can impair health of future generations

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets. [More]
Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells. [More]
Study examines effectiveness of high-load resistance training in improving older men’s bone strength

Study examines effectiveness of high-load resistance training in improving older men’s bone strength

Big improvements in bone and muscle strength with no injuries is expected to be the outcome of a Griffith University study training men aged over 50 with low bone mass. [More]
Researchers clarify cause of heart arrhythmia in myotonic dystrophy

Researchers clarify cause of heart arrhythmia in myotonic dystrophy

An international joint research group found that the cause of heart arrhythmia in myotonic dystrophy was RNA abnormalities in the sodium channel in the heart, clarifying the symptom's mechanism. This finding will be helpful in prevention and early intervention of death in this disease, leading to the development of new treatment. [More]
Study evaluates effectiveness of robotic approach over manual ablation in treating heart arrhythmia

Study evaluates effectiveness of robotic approach over manual ablation in treating heart arrhythmia

Whether ablation of the highest-risk heart arrhythmia is best handled by a robot or the hands of an electrophysiologist should be answered by an international comparison of the two. [More]
CD38 enzyme linked to age-related metabolic decline

CD38 enzyme linked to age-related metabolic decline

Researchers at Mayo Clinic have identified the enzyme, called CD38, that is responsible for the decrease in nicotinamide adenine dinucleotide (NAD) during aging, a process that is associated with age-related metabolic decline. [More]
New UCLA study reveals strategy to fight against pesticide-associated Parkinson’s disease

New UCLA study reveals strategy to fight against pesticide-associated Parkinson’s disease

Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson's disease, although the mechanism by which the compounds exert their toxicity on the brain has not been completely understood. [More]
CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method of measuring LBM takes changes in individual body composition into account for better staging of disease and therapy monitoring, say researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. [More]
Scientists aim to heal failing heart with the body’s own cells

Scientists aim to heal failing heart with the body’s own cells

Babies born with heart defects live longer than ever thanks to advances in the diagnosis and treatment of congenital heart disease. Yet, despite substantial progress, many continue to face bleak odds, lifelong medication, multiple surgeries and progressive heart failure, often requiring a transplant. [More]
Study shows similarity between embryonic and reprogrammed stem cells

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth. [More]
Anti-TNF therapy offers new hope to JDM patients

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM). [More]
Innovative advances in medical paediatric orthotics shared at Primary Care and Public Health 2016

Innovative advances in medical paediatric orthotics shared at Primary Care and Public Health 2016

Innovative, clinician-led advances in orthotic techniques have the capacity to dramatically improve short term progress and long term outcomes for selective dorsal rhizotomy and scoliosis patients as well as patients with neurological disorders affecting movement. [More]
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