Neocortex News and Research

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Environmental stressors linked to fetal brain development challenges

Review article in the journal Antioxidants explores the impact of environmental factors on fetal and neonatal brain development, emphasizing the role of inflammation and oxidative stress from maternal stressors.

15 Apr 2024

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Study reviews the intricate relationship between diet, gut microbiome diversity, and Alzheimer’s disease progression, suggesting gut health could play a key role in managing the disease.

3 Feb 2024

AI model unveils how memories blend reality and imagination

Recent advances in generative AI help to explain how memories enable us to learn about the world, re-live old experiences and construct totally new experiences for imagination and planning, according to a new study by UCL researchers.

19 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

New insights into evolution of the “little brain”

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex – a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception.

29 Nov 2023

Ultra-high resolution MRI scanner offers new opportunities for brain research

An intense international effort to improve the resolution of magnetic resonance imaging (MRI) for studying the human brain has culminated in an ultra-high resolution 7 Tesla scanner that records up to 10 times more detail than current 7T scanners and over 50 times more detail than current 3T scanners, the mainstay of most hospitals.

27 Nov 2023

Is COVID-19 a risk factor for Alzheimer's disease?

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

23 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

The association of dietary patterns with Alzheimer’s disease and related dementia symptomology

A new paper discusses the impact of diet on the risk of AD, in which researchers describe the interrelationship between specific nutrients, dietary patterns, other risk factors for AD, and psychosocial factors driving these patterns.

24 Jul 2023

Mathematical neural network theory explains how memories are consolidated in the brain

How useful a memory is for future situations determines where it resides in the brain, according to a new theory proposed by researchers at HHMI"s Janelia Research Campus and collaborators at UCL.

20 Jul 2023

Is an increase in cortisol levels associated with impaired working-memory retrieval and recognition in students?

Researchers examined the memory scores and electroencephalogram profiles of students to understand exam-induced stress and anxiety among the student population.

4 May 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Neocortex News and Research

Environmental stressors linked to fetal brain development challenges

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

AI model unveils how memories blend reality and imagination

Imbalances in folic acid and vitamin B12 can alter brain development in mice

New insights into evolution of the “little brain”

Ultra-high resolution MRI scanner offers new opportunities for brain research

Is COVID-19 a risk factor for Alzheimer's disease?

Research explains the reason behind delay in therapeutic action of antidepressants

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

The association of dietary patterns with Alzheimer’s disease and related dementia symptomology

Mathematical neural network theory explains how memories are consolidated in the brain

Is an increase in cortisol levels associated with impaired working-memory retrieval and recognition in students?

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

Study reveals new clues to the underlying cause of FXS symptoms

“Zone of uncertainty” communicates with the neocortex to rapidly control memory formation

What are the effects of prenatal exposure to alcohol and marijuana on fetal development?

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

During sleep, the hippocampus and neocortex interact in ways that are key to memory formation

UCI neuroscientists discover underlying mechanisms behind brain’s high-level work

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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