Nephrology News and Research RSS Feed - Nephrology News and Research

Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.
Study: Older adults with high blood pressure appear to have good kidney health after donation

Study: Older adults with high blood pressure appear to have good kidney health after donation

With proper monitoring, kidney donation may be safe for individuals with high blood pressure, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The study found that while hypertension can have negative effects on the kidneys, older adults with the condition appear to have good kidney health following donation. [More]
Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Results from the Phase 2 RESONATE-17 (PCYC-1117) study show IMBRUVICA (ibrutinib) was associated with an 82.6 percent investigator-assessed overall response rate (ORR; the primary endpoint) and a 79 percent progression-free survival (PFS) rate at 12 months in people living with relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have a genetic mutation known as deletion 17p (del 17p). [More]
Three IU researchers receive $2.1 million to develop computational biology models of liver toxicity

Three IU researchers receive $2.1 million to develop computational biology models of liver toxicity

Three Indiana University professors have received $2.1 million to develop a computational model of acetaminophen-induced liver failure -- the leading cause of liver failure in the United States -- by using advanced microscopic and computational technologies that allow scientists to see into the liver of a living animal. [More]
New therapeutic targets can prevent scarring within transplanted kidneys

New therapeutic targets can prevent scarring within transplanted kidneys

Kidneys donated by people born with a small variation in the code of a key gene may be more likely, once in the transplant recipient, to accumulate scar tissue that contributes to kidney failure, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published today in the Journal of Clinical Investigation. [More]
UC San Diego Health System, IVFCMG partner to enhance health care services

UC San Diego Health System, IVFCMG partner to enhance health care services

UC San Diego Health System and Imperial Valley Family Care Medical Group are pleased to announce a comprehensive affiliation that will enhance the depth and quality of multi-specialty health care services and clinical trials available to patients in the Imperial Valley and surrounding communities. [More]
Presence of certain proteins in HDL can lead to cardiovascular risk

Presence of certain proteins in HDL can lead to cardiovascular risk

A current study by the MedUni Vienna has shown that changes to the "good cholesterol" HDL (High-Density Lipoprotein) can be associated with cardiovascular diseases: by developing a new laboratory test, scientists at the Institute of Medical Genetics and the Department of Nephrology & Dialysis (University Department of Internal Medicine III) at the MedUni Vienna have demonstrated for the first time that the presence of certain proteins in the HDL can lead to an increased risk of cardiovascular disease and mortality. [More]
UL professor awarded HRB grant to improve understanding of Acute Kidney Injury

UL professor awarded HRB grant to improve understanding of Acute Kidney Injury

It is estimated that at least 1 in 5 hospitalised adults develop Acute Kidney Injury (AKI). Emerging evidence suggests that AKI: is under-recognised in clinical practice; predicts an accelerated risk of end-stage kidney disease (ESKD), and may be a risk amplifier for many other chronic diseases with death rates in excess of 20%. [More]
Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine. [More]
Kidney disease patients can benefit from simple and structured exercise

Kidney disease patients can benefit from simple and structured exercise

Simple yet structured exercise can significantly improve kidney disease patients' quality of life as well as decrease their pain, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). [More]
Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Eighty percent of kidney dialysis patients surveyed were not adequately prepared in the event of an emergency or natural disaster that shut down their dialysis center. [More]
3SBio enters into exclusive license agreement with PharmAbcine for Tanibirumab

3SBio enters into exclusive license agreement with PharmAbcine for Tanibirumab

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive license with PharmAbcine, Inc. for the development, manufacturing and marketing of Tanibirumab, an anti-VEGFR2/KDR antibody for cancer in the territory of Greater China (including Mainland China, Taiwan, Hong Kong and Macau) and several emerging countries, including Thailand, Brazil and Russia. [More]
Researchers discover second protein associated with membranous nephropathy

Researchers discover second protein associated with membranous nephropathy

An international team of researchers from France, Germany, and the US have identified a protein that turns a person's immune system against itself in a form of kidney disease called membranous nephropathy (MN). The new research was presented at ASN Kidney Week 2014 in Philadelphia and published online in the New England Journal of Medicine. [More]

New preclinical study shows RG-012 may provide therapeutic benefit for Alport syndrome patients

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that positive new preclinical data was presented on RG-012 for the treatment of renal dysfunction in Alport syndrome patients at the American Society of Nephrology's Kidney Week 2014 meeting being held November 11-16, 2014 in Philadelphia, PA. [More]
NIH study finds limited kidney benefit from more rigorous blood pressure treatment

NIH study finds limited kidney benefit from more rigorous blood pressure treatment

Using two drugs was no more effective than a single drug in slowing disease progression in people with autosomal dominant polycystic kidney disease (ADPKD), according to two studies funded by the National Institutes of Health. One of the studies also showed that rigorous blood pressure treatment slowed growth of kidney cysts, a marker of ADPKD, but had little effect on kidney function compared to standard blood pressure treatment. [More]

DaVita Kidney Care, Medtronic partner to better understand cardiovascular health in ESRD patients

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and leading provider of kidney care services, announced today a collaboration with Medtronic, Inc., to better understand cardiovascular health in end stage renal disease (ESRD) patients. [More]
Mediterranean diet is good for your kidneys

Mediterranean diet is good for your kidneys

New research indicates that adopting a Mediterranean-style diet can reduce the risk of developing chronic kidney disease by 50%. [More]

Fewer women than men receive dialysis treatment for chronic kidney disease

Women with chronic kidney disease receive dialysis treatment far less often than men. However, women suffer more commonly than men from kidney disease. A publication by the MedUni Vienna and the Arbor Research Collaborative for Health, USA, has highlighted this difference based on international patient data. [More]
MGH, MIT partner to accelerate development of diagnostic tools and therapies

MGH, MIT partner to accelerate development of diagnostic tools and therapies

A novel partnership between Massachusetts General Hospital and Massachusetts Institute of Technology is addressing three major challenges in clinical medicine – improving the diagnosis of disease, developing new approaches to prevent and treat infectious and autoimmune diseases, and developing more accurate methods of diagnosing and treating major neurodegenerative and psychiatric diseases. While individual collaborations between MGH and MIT investigators are nothing new, this formalized strategic partnership is designed to accelerate the development of diagnostic tools and therapies. [More]
Experts to share innovative approaches to improve kidney health at ASN Kidney Week 2014

Experts to share innovative approaches to improve kidney health at ASN Kidney Week 2014

The world's largest gathering of kidney health professionals-Kidney Week 2014-will take place November 11-16 in Philadelphia, PA. The annual meeting of the American Society of Nephrology, Kidney Week will showcase new scientific and clinical advances in nephrology from across the globe. [More]
CorMedix submits IND application to FDA for Neutrolin

CorMedix submits IND application to FDA for Neutrolin

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiac, renal and infectious disease, is pleased to announce that an Investigational New Drug application (IND) for Neutrolin was submitted to the United States Food and Drug Administration on Wednesday, September 24, 2014. [More]