Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

During the past decade, researchers have identified new ways to detect the earliest biological signs of Alzheimer's disease.

22 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

Researchers from Drexel University reversed symptoms of Alzheimer's disease in fruit flies by restoring the balance between two epigenetic enzymes that regulate gene expression, a study shows.

15 May 2018

New tool provides high accuracy and precision in analyzing disease and drug effects

A new protein analysis tool developed at the University at Buffalo could vastly increase the speed and precision with which disease and drug effects are analyzed.

11 May 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Scientists at The Scripps Research Institute have devised what they call a "neuronal cookbook" for turning skin cells into different types of neurons.

10 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

3D structures of nicotine receptor could lead to new ways for treating addiction

UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.

3 May 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

Study reveals surprising insights into RNA-binding proteins

A host of special molecules called nuclear RNA-binding proteins (RBPs), when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

20 Apr 2018

Protein linked with Alzheimer's disease affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies.

13 Apr 2018

Adult-onset degenerative disease mechanism begins much earlier than previously thought

The disease mechanism for adult-onset progressive degenerative diseases begins much earlier than previously thought, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

30 Mar 2018

Researchers reveal molecular structure of 'anti-aging' protein

Researchers from UT Southwestern's Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Internal Medicine's Division of Nephrology recently published work in Nature that reveals the molecular structure of the so-called "anti-aging" protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic processes.

29 Mar 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.

23 Mar 2018

Research offers new understanding about cause of Parkinson's disease

Until very recently, Parkinson's had been thought a disease that starts in the brain, destroying motion centers and resulting in tremors and loss of movement.

21 Mar 2018

Neurodegeneration News and Research

Further Reading

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

New study could have important implications for cellular aging

Researchers demonstrate new strategy for stimulating autophagy

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

New tool provides high accuracy and precision in analyzing disease and drug effects

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Researchers characterize new protein that plays key role in genetic stability of cells

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

3D structures of nicotine receptor could lead to new ways for treating addiction

Study explains how colon cancer cells spread to the liver

Study reveals surprising insights into RNA-binding proteins

Protein linked with Alzheimer's disease affects different brain cells differently

Adult-onset degenerative disease mechanism begins much earlier than previously thought

Researchers reveal molecular structure of 'anti-aging' protein

Researchers uncover cause of rare childhood neurodegenerative disease

Research offers new understanding about cause of Parkinson's disease

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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