Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2).

4 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Evidence reveals ferroptosis's critical role in male reproductive health

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2 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Study investigates association between menopause stage and cerebral hemodynamics

Driven by changing estrogen levels, the menopause transition has a major influence on physiology during aging.

27 Sep 2023

Study upends common belief in what triggers Parkinson's disease

A new Northwestern Medicine study challenges a common belief in what triggers Parkinson's disease.

15 Sep 2023

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS).

14 Sep 2023

Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

Study identifies cellular processes that likely lead to Parkinson's disease

Parkinson's disease, characterized by various motor dysfunctions, is the second most common neurodegenerative disorder in the world. It is known that specific gene mutations that are passed down through families are responsible for some cases of Parkinson's disease.

11 Sep 2023