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Scratching itchy skin causes the brain to release serotonin, intensifies itchy feeling

Scratching itchy skin causes the brain to release serotonin, intensifies itchy feeling

Turns out your mom was right: Scratching an itch only makes it worse. New research from scientists at Washington University School of Medicine in St. Louis indicates that scratching causes the brain to release serotonin, which intensifies the itch sensation. [More]
Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells – motor neurons – in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis. [More]
Nanostructures around brain cells may have role in central nervous system function

Nanostructures around brain cells may have role in central nervous system function

An accumulation of a protein called amyloid-beta into large insoluble deposits called plaques is known to cause Alzheimer's disease. One aspect of this illness that has not received much attention is which role the structure of the brain environment plays. [More]
Teen binge drinking effects may last a lifetime, suggests UMass Amherst study

Teen binge drinking effects may last a lifetime, suggests UMass Amherst study

Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, say neuroscience researcher Heather N. Richardson and her colleagues at the University of Massachusetts Amherst and Louisiana State University. [More]
Study sheds light on why we remember some things and not others

Study sheds light on why we remember some things and not others

Why do we remember some things and not others? In a unique imaging study, two Northwestern University researchers have discovered how neurons in the brain might allow some experiences to be remembered while others are forgotten. It turns out, if you want to remember something about your environment, you better involve your dendrites. [More]
Nano-sized discovery helps explain bipolar disorder

Nano-sized discovery helps explain bipolar disorder

A nano-sized discovery by Northwestern Medicine® scientists helps explain how bipolar disorder affects the brain and could one day lead to new drug therapies to treat the mental illness. [More]
Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease. [More]
Isis Pharmaceuticals provides update on Phase 2 clinical studies of ISIS-SMN Rx in children with SMA

Isis Pharmaceuticals provides update on Phase 2 clinical studies of ISIS-SMN Rx in children with SMA

Isis Pharmaceuticals, Inc. today provided an update on its ongoing open-label Phase 2 clinical studies of ISIS-SMN Rx in infants and children with spinal muscular atrophy at the 19th International World Muscle Society (WMS) Congress in Berlin, Germany. [More]
UCI to receive $8 million from NIH to study brain cell activity in motor neuron disorders

UCI to receive $8 million from NIH to study brain cell activity in motor neuron disorders

UC Irvine will receive $8 million from the National Institutes of Health to establish one of six national centers dedicated to creating a database of human cellular responses that will accelerate efforts to develop new therapies for many diseases. [More]
UT Arlington scientists explore how fluid flow could play significant role in neuronal growth

UT Arlington scientists explore how fluid flow could play significant role in neuronal growth

A University of Texas at Arlington team exploring how neuron growth can be controlled in the lab and, possibly, in the human body has published a new paper in Nature Scientific Reports on how fluid flow could play a significant role. [More]
Kessler Foundation's Guang Yue to study impact of high-effort training on muscle weakness

Kessler Foundation's Guang Yue to study impact of high-effort training on muscle weakness

Guang Yue, PhD, of Kessler Foundation has been awarded an NIH grant for$1,962,767 to study the impact of high-effort training on the muscle weakness that impairs quality life among many individuals with cancer. [More]
Groundbreaking study tracks precise path of rabies to the central nervous system

Groundbreaking study tracks precise path of rabies to the central nervous system

Rabies causes acute inflammation of the brain, producing psychosis and violent aggression. The virus, which paralyzes the body's internal organs, is always deadly for those unable to obtain vaccines in time. Some 55,000 people die from rabies every year. [More]
Allen Institute for Brain Science receives $8.7 million NIH grant to explore synapses

Allen Institute for Brain Science receives $8.7 million NIH grant to explore synapses

The Allen Institute for Brain Science, in a project led by Stephen Smith, Ph.D., Senior Investigator, has been awarded an $8.7 million, five-year Transformative Research Award from the National Institutes of Health to lead the creation of a publicly accessible model of synapse populations in mouse and human brains. [More]
Research findings could help find ways to enhance overall learning, memory

Research findings could help find ways to enhance overall learning, memory

The more curious we are about a topic, the easier it is to learn information about that topic. New research publishing online October 2 in the Cell Press journal Neuron provides insights into what happens in our brains when curiosity is piqued. [More]
Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

A review article published online in Behavioral Brain Research provides novel insight into changes that happen in the brain as a result of chronic alcohol exposure that can lead to disruptions in the sleep cycle. [More]

Scientists show how individual neurons in the human brain react to morphed faces

An international team of scientists, involving Professor Rodrigo Quian Quiroga, director of the Centre for Systems Neuroscience and Head of Bioengineering at the University of Leicester, has shown how individual neurons in the human brain react to ambiguous morphed faces. [More]
Understanding how neurons encode information

Understanding how neurons encode information

Nathan Urban, interim provost and the Dr. Frederick A. Schwertz Distinguished Professor of Life Sciences, and Robert Kass, professor of statistics and machine learning, have received a $930,000 grant from the National Science Foundation to apply biological and statistical neuroscience approaches in order to create a better overall understanding of how neurons encode information. [More]
Cedars-Sinai to participate in a consortium studying motor neuron disorders

Cedars-Sinai to participate in a consortium studying motor neuron disorders

Investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have received a grant from the National Institutes of Health to participate in a consortium taking the study of motor neuron disorders - such as Lou Gehrig's disease and spinal muscular atrophy - to a new, comprehensive perspective. [More]
Study shows how complex tactile sensations are coded at cellular level in brain

Study shows how complex tactile sensations are coded at cellular level in brain

The traditional understanding in neuroscience is that tactile sensations from the skin are only assembled to form a complete experience in the cerebral cortex, the most advanced part of the brain. [More]
New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses. [More]