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Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Traditional light microscopy techniques such as confocal and wide-field are diffraction-limited in resolution, which is about 200 nm laterally (in xy) and 500 to 600 nm axially (in z). Features that are closer than the diffraction limit will appear blurred in the image. [More]
Scientist uses stem cells derived from dental pulp to return hearing to deaf people

Scientist uses stem cells derived from dental pulp to return hearing to deaf people

Deafness is a condition in which the hearing diminishes or disappears; currently there are few procedures to treat because it often is irreversible. Also, according to the World Health Organization (WHO), the disease globally affects 360 million people. [More]
Scientists find way to reverse malfunctioning protein clumps involved in ALS

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery. [More]
Research re-opens door to possibility of stopping ongoing brain damage

Research re-opens door to possibility of stopping ongoing brain damage

A breakthrough in understanding how brain damage spreads - and how it could potentially be limited - has been made through a collaboration between neuroscientists and engineers at the Universities of Dundee and Strathclyde. [More]
Memory and language deeply linked via the hippocampus, new experiment shows

Memory and language deeply linked via the hippocampus, new experiment shows

A new study shows that when you finish your spouse's sentences or answer a fill-in-the-blank question, you're engaging the brain's relay station for memories, the hippocampus. [More]
De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division. [More]
Researchers propose new explanation for symptoms of fragile X syndrome

Researchers propose new explanation for symptoms of fragile X syndrome

Until recently, scientists thought they understood one of the underlying causes of fragile X syndrome, the most common inherited cause of intellectual disability in the United States. [More]
Researchers reveal previously unknown role of glutamate in neuromuscular development

Researchers reveal previously unknown role of glutamate in neuromuscular development

For decades, scientists thought acetylcholine was the only neurotransmitter responsible for controlling how muscles and nerves are wired together during development. [More]
Research findings point to potential new targeted therapy for SMA

Research findings point to potential new targeted therapy for SMA

For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell. [More]
BIDMC scientists shed light on how hunger affects the brain’s response to visual food cues

BIDMC scientists shed light on how hunger affects the brain’s response to visual food cues

Our brain pays more attention to food when we are hungry than when we are sated. Now a team of scientists at Beth Israel Deaconess Medical Center has shed light on how the needs of the body affect the way the brain processes visual food cues. [More]
IRB Barcelona researchers reveal new strategy to obtain barrel-shaped amyloid-beta aggregates

IRB Barcelona researchers reveal new strategy to obtain barrel-shaped amyloid-beta aggregates

Researchers at IRB Barcelona describe for the first time how to prepare a specific type of aggregate of the amyloid-beta protein with the ability to perforate the cell membrane. [More]
Researchers discover network of neural regions involved in spread of seizures

Researchers discover network of neural regions involved in spread of seizures

A flurry of coordinated activity in a brain-spanning network of neurons may sound like the formation of a brilliant new idea, but it is actually the description of a seizure. Understanding why and how this synchronization spreads would be a critical tool in treating severe epilepsy. [More]
Research provides scientific evidence for adverse effects of cannabis intake on brain development

Research provides scientific evidence for adverse effects of cannabis intake on brain development

Researchers have clarified important mechanisms involved in the formation of neural circuits in the brain. [More]
Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients. [More]
Mathematical model explains molecular events linked to learning and memory formation

Mathematical model explains molecular events linked to learning and memory formation

A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain. [More]
UCSB neuroscientist provides new understanding of how the brain uses perception to guide action

UCSB neuroscientist provides new understanding of how the brain uses perception to guide action

A UC Santa Barbara researcher studying how the brain uses perception of the environment to guide action has a new understanding of the neural circuits responsible for transforming sensation into movement. [More]
Research could pave way for more effective and safer anti-epilepsy drugs

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications. [More]
Researchers describe how genetic mutations cause unnamed neurological disorder

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder. [More]
Learning foreign languages can enhance the brain's ability to code information

Learning foreign languages can enhance the brain's ability to code information

Scientists from the Higher School of Economics together with colleagues from the University of Helsinki have discovered that learning foreign languages enhances the our brain's elasticity and its ability to code information. [More]
NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Microglia are cells that combat various brain diseases and injuries by swallowing foreign or disruptive objects and releasing molecules that activate repair mechanisms. [More]
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