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Research by UCI, Salk Institute points to novel therapies for minimizing stroke-induced brain damage

Research by UCI, Salk Institute points to novel therapies for minimizing stroke-induced brain damage

​By discovering a new mechanism that allows blood to enter the brain immediately after a stroke, researchers at UC Irvine and the Salk Institute have opened the door to new therapies that may limit or prevent stroke-induced brain damage. [More]

Study reveals factors that contribute to eye mobility disorder

Imagine you cannot move your eyes up, and you cannot lift your upper eyelid. You walk through life with your head tilted upward so that your eyes look straight when they are rolled down in the eye socket. [More]
Scientists create new model of memory that provides complete picture of how memory works

Scientists create new model of memory that provides complete picture of how memory works

Scientists at the Salk Institute have created a new model of memory that explains how neurons retain select memories a few hours after an event. [More]
Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

​A class of drugs developed to treat immune-related conditions and cancer - including one currently in clinical trials for glioblastoma and other tumors - eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers. [More]
New mouse study indicates that mutant protein in muscle cells is responsible for SBMA

New mouse study indicates that mutant protein in muscle cells is responsible for SBMA

Sometimes known as Kennedy's disease, spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. [More]

Autism in adolescents appears to be associated with atypical connectivity in brain, says study

Autism spectrum disorder (ASD) in adolescents appears to be associated with atypical connectivity in the brain involving the systems that help people infer what others are thinking and understand the meaning of others' actions and emotions. [More]
Researchers develop novel tools to learn how astrocytes listen in on neuronal communication

Researchers develop novel tools to learn how astrocytes listen in on neuronal communication

​Everything we do - all of our movements, thoughts and feelings - are the result of neurons talking with one another, and recent studies have suggested that some of the conversations might not be all that private. [More]
Parabon launches Compute Against Alzheimer's Disease research initiative

Parabon launches Compute Against Alzheimer's Disease research initiative

Parabon Computation announced today the launch of the Compute Against Alzheimer's Disease (CAAD) research initiative, which will accelerate investigations into the causes and risks of Alzheimer's Disease (AD) through the application of large-scale computational capacity donated by concerned citizens and organizations. [More]
Researchers coax human embryonic stem cells to turn into working spinal cord cells

Researchers coax human embryonic stem cells to turn into working spinal cord cells

The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows. [More]
Study confirms neurobiological origin of attention-deficit disorder

Study confirms neurobiological origin of attention-deficit disorder

A study, carried out on mice, has just confirmed the neurobiological origin of attention-deficit disorder (ADD), a syndrome whose causes are poorly understood. Researchers from CNRS, the University of Strasbourg and INSERM1 have identified a cerebral structure, the superior colliculus, where hyperstimulation causes behavior modifications similar to those of some patients who suffer from ADD. [More]

Scientists discover potential cause of Parkinson’s disease

Researchers have discovered a process that appears to explain how a well known enzyme mutation triggers the neural deterioration seen in Parkinson’s disease. [More]
UCL scientists find new way to artificially control paralyzed muscles using light

UCL scientists find new way to artificially control paralyzed muscles using light

​A new way to artificially control muscles using light, with the potential to restore function to muscles paralysed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King's College London. [More]

Harvard stem cell scientists discover potential treatment for amyotrophic lateral sclerosis

Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for amyotrophic lateral sclerosis (ALS)-Lou Gehrig's disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital to design an initial clinical trial testing the safety of the treatment in ALS patients. [More]

Endurance sport keeps both muscles and nerves fit

Endurance sport does not only change the condition and fitness of muscles but also simultaneously improves the neuronal connections to the muscle fibers based on a muscle-induced feedback. [More]

Human motor neurons can be quickly generated from stem cells, say researchers

Researchers report they can generate human motor neurons from stem cells much more quickly and efficiently than previous methods allowed. The finding, described in Nature Communications, will aid efforts to model human motor neuron development, and to understand and treat spinal cord injuries and motor neuron diseases such as amyotrophic lateral sclerosis (ALS). [More]
Cedars-Sinai earns grant to conduct clinical trial of gene therapy product for patients with Lou Gehrig's disease

Cedars-Sinai earns grant to conduct clinical trial of gene therapy product for patients with Lou Gehrig's disease

The Cedars-Sinai Regenerative Medicine Institute has received a $2.5 million grant from the Department of Defense to conduct animal studies that, if successful, could provide the basis for a clinical trial of a gene therapy product for patients with Lou Gehrig's disease, also called amyotrophic lateral sclerosis, or ALS. [More]
Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

A new discovery suggests it could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma. [More]
Experimental anticancer compound appears to reverse behaviors associated with schizophrenia

Experimental anticancer compound appears to reverse behaviors associated with schizophrenia

Johns Hopkins researchers say that an experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness. [More]
Potassium boost improves walking, prolongs survival in mouse model of Huntington's disease

Potassium boost improves walking, prolongs survival in mouse model of Huntington's disease

Tweaking a specific cell type's ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington's disease, reports a UCLA study published March 30 in the online edition of Nature Neuroscience. The discovery could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans. [More]

Mirror neuron system faulty in schizophrenia patients

An imaging study suggests that a faulty mirror neuron system could underlie the social dysfunction seen in patients with schizophrenia. [More]