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Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report. [More]
Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV. [More]
Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Researchers from the University of California and Cardiff University have made a breakthrough in the understanding of AIDS-related dementia, discovering the role of a neuron protein which was also found to affect learning abilities in healthy subjects. [More]
Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

Traumatic brain injury (TBI) is one of the leading causes of disability and death in infants and children in the United States, with more than half a million affected annually, according to the Centers for Disease Control and Prevention. [More]
Orphan Disease Center establishes new initiative that focuses on ALS

Orphan Disease Center establishes new initiative that focuses on ALS

The Orphan Disease Center in the Perelman School of Medicine at the University of Pennsylvania has established a new Program of Excellence for Motor Neuron Disease. [More]
Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy. [More]
The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

The brain is home to two kinds of cells: neurons and glia, with the latter protecting the former. Glia, the stuff between neurons, are important also because they regulate and define neuron-neuron communication. [More]
Research provides new insights into how the brain processes visual information to control behavior

Research provides new insights into how the brain processes visual information to control behavior

What you see is not always what you get. And that, researchers at The Rockefeller University have discovered, is a good thing. [More]
Protein involved in neurological disorders can travel from brain to stomach

Protein involved in neurological disorders can travel from brain to stomach

Researchers of the German Center for Neurodegenerative Diseases have found that "alpha-synuclein", a protein involved in a series of neurological disorders including Parkinson's disease, is capable of travelling from brain to stomach and that it does so following a specific pathway. [More]
Acute stress can lead to delayed, long-term psychological trauma

Acute stress can lead to delayed, long-term psychological trauma

Mrs. M would never forget that day. She was walking along a busy road next to the vegetable market when two goons zipped past on a bike. One man's hand shot out and grabbed the chain around her neck. [More]
Researchers identify mechanism that generates synchronous oscillation in the brain

Researchers identify mechanism that generates synchronous oscillation in the brain

Every time we learn something new, the memory does not only need to be acquired, it also needs to be stabilized in a process called memory consolidation. [More]
C elegans could be powerful model for understanding how nervous systems produce behaviors

C elegans could be powerful model for understanding how nervous systems produce behaviors

The human brain, the most complex object in the universe, has 86 billion neurons with trillions of yet-unmapped connections. [More]
CSHL researcher-inventor hails FDA approval of new SMA drug

CSHL researcher-inventor hails FDA approval of new SMA drug

Within a week of Christmas day, a drug called nusinersen will be in the hands of doctors across the nation, who will use it, most urgently, to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA). [More]
Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration has approved SPINRAZATM (nusinersen) under Priority Review for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients. [More]
MDA celebrates FDA approval of new spinal muscular atrophy drug

MDA celebrates FDA approval of new spinal muscular atrophy drug

The Muscular Dystrophy Association today celebrated news of the U.S. Food and Drug Administration's decision to grant approval for nusinersen (brand name Spinraza), the first disease-modifying drug to treat the most common genetic cause of death in infants. [More]
UC San Diego research identifies neurons that signal direction of travel

UC San Diego research identifies neurons that signal direction of travel

Imagine you're navigating a city like New York, or any other that's laid out on a grid. Suppose you run into a roadblock as you're heading north. [More]
Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans. [More]
Generative AAE can be radically new way to discover drugs on demand

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand. [More]
Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry. [More]
Study provides new insight into brain circuitry that regulates water and food intake

Study provides new insight into brain circuitry that regulates water and food intake

Using leading-edge technology, neuroscientists at Beth Israel Deaconess Medical Center gained new insight into the brain circuitry that regulates water and food intake. [More]
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