Neurosurgery News and Research

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A quantitative analysis on the recruitment of female students in US neurosurgery programs

The authors of this article evaluated residents enrolled in US neurosurgery programs in 2021 to characterize which medical schools most successfully recruited female students into the field over a 7-year period.

21 Jun 2022

Researchers identify a signature of three genes linked to positive response to blood cancer therapy

Mount Sinai researchers have for the first time identified genes that predict a good response to a vital new therapy for a blood cancer that can have serious side effects for some patients.

16 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

COVID-19 vaccination associated with reduction in hospitalizations and mortality among heart failure patients

Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus compared to fully boosted heart failure patients, according to new research out of Mount Sinai Heart.

9 Jun 2022

Use of RAAS inhibitors reduced aneurysm rupture risk by 18%, finds study

A multi-center study of more than 3,000 people with high blood pressure and brain aneurysms found that the use of RAAS inhibitors, a class of blood pressure lowering medications, reduced the risk of an aneurysm rupture by 18%, according to new research published today in Hypertension, a peer-reviewed journal of the American Heart Association.

3 Jun 2022

Liquid biopsy could better predict immunotherapy response in lung cancer patients than tumor biopsy

Mount Sinai researchers have validated for the first time that a simple blood test called a liquid biopsy could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.

3 Jun 2022

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie neuropsychiatric disorders such as autism and schizophrenia.

1 Jun 2022

Study shows how stress has a major impact on the immune system's ability to fight infections

Acute stress can be detrimental to fighting off infection, especially COVID-19, and increases the chance of dying in mouse models.

30 May 2022

New approach could treat brain tumors and also prevent or delay recurrences

Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors.

27 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

Exercise increases levels of a chemical involved in brain cell growth, which bolsters the release of the "feel good" hormone dopamine, a new study shows. Dopamine is known to play a key role in movement, motivation, and learning.

16 May 2022

New drug inhibits growth of the most aggressive meningiomas

When a specific non-metastatic brain tumor — a meningioma — recurs after surgery and radiation treatment, a patient is normally out of options. No drugs are approved for these aggressive tumors, which occur in up to 20 percent of cases and can lead to patient disability or even death.

16 May 2022

Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the urinary tract that had invaded the muscle and therefore posed a high risk for recurrence, according to clinical trial results presented at the American Urological Association annual meeting in May.

15 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Telltale signs of concussions may be found in the gut, study suggests

A recently published study by Houston Methodist scientists suggests telltale signs of concussions might be found in the gut.

10 May 2022

New guideline provides guidance on the use of radiation therapy to treat patients with brain metastases

A new clinical guideline from the American Society for Radiation Oncology provides guidance on the use of radiation therapy to treat patients with brain metastases.

10 May 2022

Novel course in biodesign expands ability of students to create potential medical devices for the future

Educators at the Renaissance School of Medicine (RSOM) at Stony Brook University highlighted the success of their three-year, elective course in biodesign that has enabled students to expand their abilities as innovators to creating potential medical devices for the future.

9 May 2022

Research suggests some solutions to combat cancer surgery-induced climate change

In April 2021, during the Leaders Summit on Climate, President Biden announced his goal to drastically reduce the United States' greenhouse gas emissions by 2030.

9 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Neurosurgery News and Research

A quantitative analysis on the recruitment of female students in US neurosurgery programs

Researchers identify a signature of three genes linked to positive response to blood cancer therapy

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

COVID-19 vaccination associated with reduction in hospitalizations and mortality among heart failure patients

Use of RAAS inhibitors reduced aneurysm rupture risk by 18%, finds study

Liquid biopsy could better predict immunotherapy response in lung cancer patients than tumor biopsy

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

Study shows how stress has a major impact on the immune system's ability to fight infections

New approach could treat brain tumors and also prevent or delay recurrences

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

New drug inhibits growth of the most aggressive meningiomas

Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Telltale signs of concussions may be found in the gut, study suggests

New guideline provides guidance on the use of radiation therapy to treat patients with brain metastases

Novel course in biodesign expands ability of students to create potential medical devices for the future

Research suggests some solutions to combat cancer surgery-induced climate change

Researchers create models to study brain metastases that recapitulate the disease

Neuroscience - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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