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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.

28 Mar 2013

Smokers trying to quit will have better experience with varenicline, study finds

Smokers have a higher probability of quitting smoking and a better overall cessation experience when taking varenicline compared to bupropion and to placebo - unmedicated assisted smoking cessation -according to a study published in the journal JAMA Psychiatry.

28 Mar 2013

$Smoking increases risk of infection and delays healing of fractures$

Smoking increases risk of infection and delays healing of fractures

Research has long shown the negative effects cigarette smoking has on cardiovascular health. But now, a new study from the Department of Orthopaedic Surgery at the Perelman School of Medicine at the University of Pennsylvania corroborates early evidence showing that cigarette smoking leads to longer healing times and an increased rate of post-operative complication and infection for patients sustaining fractures or traumatic injuries to their bone.

25 Mar 2013

Researchers develop new device to battle against secondhand tobacco smoke

Dartmouth researchers have taken an important step in the ongoing battle against secondhand tobacco smoke. They have pioneered the development of a breakthrough device that can immediately detect the presence of secondhand smoke and even third-hand smoke.

25 Mar 2013

Study shows decreased rate of post-surgical complications in non-smokers

24 Mar 2013

Researchers invent secondhand tobacco smoke sensor that records data in real time

Making headway against a major public health threat, Dartmouth College researchers have invented the first ever secondhand tobacco smoke sensor that records data in real time, a new study in the journal Nicotine and Tobacco Research shows.

20 Mar 2013

Relighting cigarettes related to economic factors, researchers find

In what is believed to be a first of its kind study, a research member at The Cancer Institute of New Jersey and colleagues have found that an accelerating trend of smokers relighting cigarettes is related to economic factors, and the practice has implications for tobacco dependence treatment and policy.

19 Mar 2013

Quitting smoking linked with lower risk of cardiovascular disease among adults without diabetes

Among adults without diabetes, quitting smoking, compared with continuing smoking, was associated with a lower risk of cardiovascular disease despite subsequent weight gain, according to a study appearing in the March 13 issue of JAMA.

13 Mar 2013

Coffee intake during pregnancy associated with elevated risk of low birth weight

Drinking just two cups of coffee a day is associated with the risk of low birth weight. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have conducted a study on 59,000 women in collaboration with the Norwegian Institute of Public Health.

12 Mar 2013

Research roundup: Insurance coverage and access to care in Massachusetts

With increasing interest in public health problems such as obesity and alcohol and tobacco use, lawmakers are increasingly considering using policy to modify behavior. According to the authors, little is currently known about the public's willingness to accept such policies.

11 Mar 2013

Addiction risk increased after mild traumatic brain injury

A study of military personnel suggests that individuals who have suffered a mild traumatic brain injury are at increased for addiction-related disorders.

8 Mar 2013

Inflammatory marker for schizophrenia treatment resistance, severity

Levels of the inflammatory marker soluble tumor necrosis factor receptor 1 may be associated with severity of symptoms and treatment resistance in schizophrenia, say Brazilian scientists.

8 Mar 2013

Researchers identify smoking gun for environmental exposures to affect future generations

Grandmother's cigarette smoking could be responsible for her grandchild's asthma, and the recent discovery of this multi-generational transmission of disease suggests the environmental factors experienced today could determine the health of family members for generations to come, two Los Angeles Biomedical Research Institute (LA BioMed) lead researchers write in the March edition of Review of Obstetrics & Gynecology.

5 Mar 2013

Tooth loss due to periodontal disease is more prevalent among postmenopausal women

Postmenopausal women who have smoked are at much higher risk of losing their teeth than women who never smoked, according to a new study published and featured on the cover of the Journal of the American Dental Association by researchers at the University at Buffalo.

2 Mar 2013

Kaposi’s sarcoma risk factors revealed

Scientists have uncovered an intriguing relationship between the risk for Kaposi’s sarcoma, smoking, and the use of highly active antiretroviral therapy.

25 Feb 2013

Loyola offers tips to help stay healthy during shoveling season

A mild winter means many are out of practice in the fine art of snow shoveling. But bending and lifting the wrong way can lead to a trip to the emergency department.

25 Feb 2013

Tobacco-free snuff, nicotine lozenges help smokers to quit

Smokeless tobacco users who said they didn't want to quit changed their minds or significantly cut back when given nicotine lozenges or tobacco-free snuff in a Mayo Clinic study.

20 Feb 2013

'Vaccine patch' could make immunizations cheaper, easier

"An innovative new way to deliver vaccines could drastically improve the health of the third world, and even the first world, by making vaccines cheaper and easier to distribute and use," Business Insider reports, adding, "The 'vaccine patch' would be as easy to apply as a Band-Aid, and would be stable for weeks at room temperature."

16 Feb 2013

IKBKE gene plays a key role in tobacco-induced lung cancer

Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.

16 Feb 2013